颜光美药理学

颜光美药理学Tag内容描述：<p>1、第25章 治疗充血性心力衰竭的药物,Chapter 25 Drugs Used in Congestive Heart Failure,北京大学医学部 李学军,Heart failure is one of the most destructive diseases in terms of its morbidity, hospitalization rate and mortality. It occurs when the heart is no longer able to pump adequate blood to meet the need of tissues.,第一节 心力衰竭的病理生理机制和药物作用的环节,一、 交感神经激活和受体信号转导的变化 二、 肾素-血管紧张素-醛固酮系统的激活 三、 心脏重构,Various mechanisms underlie the occurrence and s。</p><p>2、Local anesthetics (LAs) can reversibly block the propagation of action potentials in peripheral nerves, and are clinically used to block local pain sensation for surgical intervention,第12章 局部麻醉药 Chapter 12 Local Anaesthetics,广西医科大学 黄仁彬,1. 局麻药对各类神经纤维，如自主物神经和运动神经都有阻断作用，使神经纤维兴奋性降低和传导减慢，以致完全抑制动作电位的产生和传导而产生局麻作用。,作用特点,作用特点,2. 作用的强弱和敏感性与神经纤维的直径大小和组织结构有关。神经突触和神经末梢对局麻药最敏。</p><p>3、第 一 节,胆 碱 酯 酶,胆碱酯酶 (cholinesterase， ChE),乙酰胆碱酯酶 (acetylcholinesterase，AChE) relatively specific for acetylcholine rapid acetylcholine hydrolysis at cholinergic synapses,胆碱酯酶 (cholinesterase， ChE),假性胆碱酯酶 (pseudocholinesterase) relatively low specificity for acetylcholine acetylcholine hydrolysis in plasma and many other tissues,AChE,分布 分子组成 同聚体 异聚体,AChE,水解过程 结合 裂解 水解,Acetyl-group transferred to serine-OH,Acetylcholine binds,Esteratic site,Anioni。</p><p>4、第18章抗精神病药物chapter 18 drugs used for treatment of Psychiatric disorders，南京医学院胡康，Psychiatric disorders，Psychiatric disorders are diseases，根据林爽用途分为抗精神病药(antipsychotic drugs)或神经稳定剂(neuroleptics)抗躁狂药(antim。</p>