糖尿病早期肾损伤应用尿糖联合尿微量白蛋白检验诊断效果观察

-精选财经经济类资料- -最新财经经济资料-感谢阅读- 1 糖尿病早期肾损伤应用尿糖联合尿 微量白蛋白检验诊断效果观察 摘要 目的 探究糖尿病早期肾 损伤应用尿糖联合尿微量白蛋白 （mAlb）检验诊断效果。 方法 选取 2016 年 2 月2017 年 2 月收治的 54 例 糖尿病患者作为研究组，取同期健康体 检正常者 49 名作为对照组，所有研究 对象均行尿糖、尿微量白蛋白检测，比 较两组联合诊断阳性率、尿糖与 mAlb 水平、诊断效能。结果 研究组尿糖检 出阳性率为 81.48%，mAlb 阳性率 74.07%，联合诊断阳性率为 90.74%， 显著高于对照组 0.00%，且联合诊断较 单独检验阳性率显著高，差异有统计学 意义（P 中国论文网 /6/view- -精选财经经济类资料- -最新财经经济资料-感谢阅读- 2 12964630.htm 关键词 糖尿病；早期肾损伤； mAlb；尿糖 中图分类号 R587 文献标识码 A 文章编号 1672-4062（2017） 05（a）-0007-02 Observation on the Effect of Urinary Glucose Combined with Urinary Microalbumin Test in Early Diabetic Nephropathy WANG Cui-ping1， ZHANG Ai- fang2 1. Department of Clinical Laboratory， Zibo City No.7 Peoples Hospital， Zibo， Shandong Province， 255040 China； 2. Department of surgery， Zibo City No.7 Peoples Hospital， Zibo， Shandong Province， 255040 China Abstract Objective This paper tries to investigate the diagnostic effect of urinary glucose combined with urinary -精选财经经济类资料- -最新财经经济资料-感谢阅读- 3 microalbumin （mAlb） test in early diabetic nephropathy. Methods 54 patients with diabetes mellitus from February 2016 to February 2017 were selected as the research group. 49 healthy persons were selected as the control group. All subjects were tested by urinary glucose and urinary microalbumin. Diagnosis of positive rate， urine glucose and mAlb levels， diagnostic efficacy were compared. Results The positive rate of urine test in the research group was 81.48%， the positive rate of mAlb was 74.07%， the positive rate of combined diagnosis was 90.74%， which was significantly higher than that of the control group of 0.00%， and the combined diagnosis was significantly higher than the single test（P0.05） ， urine glucose and mAlb levels in the research group were significantly higher than those in the control group（P0.05 ）. The difference -精选财经经济类资料- -最新财经经济资料-感谢阅读- 4 between the two groups was statistically significant （P0.05 ） ， combined diagnosis specificity rate was 66.66% （2/3） ， sensitivity rate was 94.11% （48/51） and accuracy rate was 92.59% （50/54）. Conclusion The combined detection of mAlb and urinary glucose in early diabetic nephropathy can help to improve the accuracy of diagnosis， so as to guide the early clinical treatment and promote the curative effect. It has certain clinical application and research value. Key words Diabetes； Early nephropathy； mAlb； Urinary glucose 糖尿病（DM）为一种自身免疫 性疾病，患者机体代谢处在紊乱状态， 且呈现出高血糖表现，导致患者器官损 伤、功能障碍，特别是对于肾功能的损 伤较大。DM 患者早期肾损伤无典型性 症状，易遭到忽视，随病情进展将导致 血管疾病，加重病情，从而影响治疗效 果与患者预后1。因此，临床需进行有 -精选财经经济类资料- -最新财经经济资料-感谢阅读- 5 效早期诊断，从而及早制定