四川省声学学会07学术交流论文摘要

网站：四川省声学学会 07 学术交流论文摘要 一、医学超声及超声影像学 1阴囊及其内容物病变的高频超声诊断 李永忠 庄华 文晓蓉 邱逦 卢强 （作者单位：四川大学华西医院超声科 ，EMAIL： 邮编：610041， ） 摘 要 目的 探讨高频超声对阴囊及其内容物病变的诊断价值。方法 回顾性分析我院经临床治疗或手术切除、 病理证实 469 例患者阴囊及其内容物病变的声像图表现。结果 本组 469 例阴囊及其内容物病变的病理类型有： 闭合性外伤 57 例，炎性病 变 93 例，占位病变 197 例，其它病变 122 例（睾丸扭转 49 例、隐睾 64 例、睾丸萎 缩 9 例）。本组 阴囊壁及其内容物病 变的声像 图表现各有其特点。 结论 高频超声能测量阴囊壁的厚度，清晰 显示睾丸 的形态大小及内部结构变化，据阴囊及其内容物病 变的声像图可初步判断其病理性质，从而 为临床提供可靠的影 像依据。 关键词 高频超声 阴囊及其内容物病变 The diagnosis of the diseased scrotum and testicle and epididym with high frequency ultrasonography Yongzhong Li， Zuang Hua, Xiaorong Wen，et al Abstract Objective To study the diagnosis value of scrotum and testicle and epididymal diseases with high frequency ultrasonography. Methods Retrospectively analysed the ultrasonographic appearance of the different scrotum and testicle and epididymal diseases in 469 patients verified by clinic diagnosis or pathology in our hospital. Results Of 469 cases,57 cases were with blunt scrotum and testicle trauma ,93 cases were with the inflamed diseases of scrotum and testicle and epididymal,occupied diseases in 197cases,other diseases in 122 cases（testis torsion in 49cases, undescend testis in 64 cases, testis atrophy in 9 cases）.The ultrasonographic appearance of the different scrotum and testicle and epididymal diseases had oneself characteristic. Conclusions the shape and size and inner structure of the scrotum and testicle and epididymal could be showed by high frequency ultrasonography,and its different diseases could be diagnosed elementary by the ultrasonographic appearances. Key words scrotum and testicle and epididymal diseases， high frequency ultrasonography 2瘤内注射微泡超声辐照下对空化效应的影响 卓忠雄 王红卫 皋月娟 李京京 张霞 第三军医大学新桥医院超声科（重庆市 400037；） 摘 要 目的 探讨超声辐照瘤内注射超声造影剂微泡对超声空化效 应的影响。方法 SD 大鼠 Walker-256 获瘤珠 结节 24 枚随机分为 3 组（A 组 超声辐照瘤内注射微泡、 B 组 单纯超声辐照、 C 组 单纯瘤内注射微泡）。作用后 1h 取肿瘤组织 HE 染色观察病理改 变和透射电镜观察细胞膜通透性变化。结果 瘤内注射微泡超声辐照组细胞 膜通透性明显增加、区域性 肿瘤细 胞凝固性坏死。 结论 瘤内注射微泡超声 辐照可增强的声空化效应作用。 关键词 微泡； 瘤内注射； 辐照； 空化效应 Influence to Ultrasonic Cavitation with Ultrasound Wave Irradiation Intratumoral Injected Microbubbles Zhuo Zhongxiong Wang Hongwei Gao Yuejuan et al Ultrasound Department of Xinqiao Hospital; Third Military Medical University (Chongqing city China 400037) Abstract: Purpose To investigate influence to ultrasonic cavitation with ultrasound wave irradiation intratumoral injected microbubbles. Method Twenty-four Walker-256 carcinomas were randomized 3 groups. A group was intratumoral injected microbubbles and ultrasound wave irradiation. B group was only ultrasound wave irradiation. C group was only intratumoral injected microbubbles. Result The membrane permeability of the tumor cellular membrane was palpably augmentative and the tumor celles were regionality coagulation necrosis in the group- intratumoral injected microbubbles and ultrasound wave irradiation. Cnclusion The effect of ultrasonic avatition erosion was augmented with intratumoral injected microbubbles and sound wave irradiation. Keywords: Mirovesicle; Intratumoral injected; Irradiance; Cavatition erosion 3超声引导经皮穿刺肿瘤组织条注射法建立VX2兔肝癌模型 李京京,卓忠雄,王冬,王宏卫,张霞 (第三军医大学附属新桥医院超声诊断科,重庆 400037) 摘 要 目的 探寻超声引导经皮穿刺肿瘤组织条注射法与其它种植方法建立兔VX2肝癌模型的异同。 方法 30只 新西兰白兔，随机分 为3组，每 组10 只。A组：超声引导经皮穿刺肿瘤组织条注射法；B组：超声引导经皮穿刺肿瘤细 胞悬液注射法；C组：开腹瘤组织块 包埋种植法。 观察各组肿瘤的生长 特点及其接种成瘤率。结果 三种不同的植瘤 方法均能成功建立移植性VX2兔肝癌模型。接种成瘤率：A组为90%、 B组为90%、C组为100%，组间比较，差异无 统计学意义。单发 率：A组为90%、B 组为20% 、C组为80%；生存时间 ：A组为43.25.6d、B组为34.53.6d 、C组为 41.23.5d，B组与A、 C组相比，差异有显著统计学意义。 结论 超声引导经皮穿刺肿瘤组织条注射法种植建立兔 VX2肝癌模型优于其它种植方法；符合本课题实验研究需求。 关键词 兔；VX2肝癌；介入超声 Establishment of VX2 Liver Cancer Model in Rabbit by Ultrasound Guided Puncture Injecting Tumor Tissue Institia Method Li Jing-jing,Zhuo Zhong-xiong, Wang Dong, etal (Department of Ultrasound , Xinqiao Hospital , Third Military Medical University , Chongqing 400037 , China) Abstract : Objective To explore different means of VX2 liver cancer model in rabbit with ultrasound guided puncture tumor tissue injection Method and other implanting methods. Methods Thirty New Zealand white rabbits were randomly divided into three groups, ten rabbits in each group . Group A: ultrasound guided puncture injecting tumor tissue institia method; Group B: Ultrasound guided puncture injecting VX2 tumor fragment suspension; Group C: tumor fragments were embedded via laparotomy. The growth feature of different groups and the ratio of tumor inoculation were observed. Results The VX2 carcinoma model was made success fully in rabbits with three methods, and the ratio for carcinoma was 90%、90% and 100%,respectively, there were no significant differences between the three groups. Single noeud ratio for carcinoma was 90%、20% and 80% respectively; survival time was 43.25.6d、34.53.6d and 41.23.5d respectively, the differences between group B versus group A and group B versus group C were statistically significant. Conclusion Establishment of VX2 Liver Cancer Model in Rabbit by Ultrasound guided puncture injecting tumor tissue institia Method surpass other implanting methods,and it meets the needs of the experiment. Key words: Rabbit; VX2 carcinoma; Interventional Ultrasound 4真两性畸形的超声诊断价值 李永忠 1，庄华 1 ，温 晓玲 2，黄鲁刚 3 (四川大学华西医院超声科 邮编 610041 Email: ) 【摘 要】 目的 探讨超声诊断真两性畸形的临床价值，以提高对真两性畸形的超声诊断水平。 方法 回顾性分析 15 例真两性畸形的临床及超声资料。结果 真两性畸形为 15 例中，其超声诊断提示真两性畸形 12 例（符合率 80.0%）。结论 超声可探 查患者是否存在性腺、子宫、前列腺及生殖管道等组织器官，并了解其位置、形态结构等 情况，为 患者的性 别选择提供客观 的影像学依据，因此超声 对真两性畸形的 诊断有着重要的价值。 【关键词】真两性畸形 超声诊断 中图分类号 R445.1；R711.1 The Clinic Value of The Ultrasonographic Diagnosis in True Hermaphroditism ngzhong Li，Zuang Hua et al (Department of Ultrasound , Xinqiao Hospital , Third Military Medical University , Chongqing 400037 , China) Abstract Objective:To studied the clinical value of ultrasonic diagnosis in tue hermaphroditism, meanwhile to sublimate the clinical knowledge of tue hermaphroditism and ultrasonic diagnosis level . Methods: To analysed retrospectively the clinical and the ultrasonographic data of 15 tue hermaphroditism cases . Results: Of 15 truehermaphroditism cases，12 cases of true hermaphroditism （80.0%）were diagnosed by ultrasonography. Conclusion: The position and morphosis of the gonad and uterus and prostate and so on could be detected by ultrasonography.So it would be important clinical value that the true hermaphroditism would be diagnosed by ultrasonography. key words true hermaphroditism ，ultrasonicdiagnosis 5卡 铂 缓 释 微 球 体 外 释 药 机 制 研 究 卓忠雄 皋月娟 王红卫 李京京 张霞 丁俊 （第三军医大学新桥医院超声 重庆市 400037；） 摘 要 ： 目 的 探 索 卡 铂 PLGA 缓 释 微 球 （微 球 ）体 外 释 药 特 性 。 方 法 O/O 型 乳 化 溶 剂 挥 发 法 制 备 微 球 ；微 球 在 磷 酸 盐 缓 冲 溶 液 中 释 放 ，不 同 时 相 取 样 计 算 卡 铂 释 放 量 并 以 卡 铂 最 初 投 药 量 百 分 率 表 达 ；扫 描 电 镜 观 察 微 球 超 微 结 构 变 化 。 结 果 微 球 初 始 形 态 呈 球 形 圆 光 滑 整 ，释 放 较 稳 定 ，曲 线 平 稳 ； 缓冲液中微球随降解时间延长微球表面皱缩及孔洞随之增加，微球中卡铂主要通过空隙溶解与 扩散。结 论 微球药物释放早期以扩散为主，后期以降解及扩散联合作用。 关 键 词 ： 卡铂；微球；释药；机理 Study of Carboplatin-loaded PLGA Microspheres in Vitro Drug Releasing Mechanism Zhuo Zhongxiong Gao Yuejuan Wang Hongwei et al （Ultrasound Department of Xinqiao Hospital; Third Military Medical University(Chongqing ity China 400037) ABSTRACT Purpose To explore characteristics of carboplatin-loaded PLGA microspheres vitro drug. releasing Method The microspheres were prepared with oil in oil. The microspheres released carboplatin in phosphate buffer solution. The released carboplatin dosages were computed on different phases with initial dosage percentage express. The ultramicrostructure changes of the microspheres were observed with the scanning electron microscope. Result The incipient shape of the microsphere was circular and slick. The drug. releasing speed was stable and the drug. releasing curve was gently. The crimples and the loophole of the microspheres surface increased gradually by degradation time extend in phosphate buffer solution. The carboplatines in the microspheres were dissolved and were diffused through the loopholes. Conclusion The microsphere drug. releasing was principal by diffusion at initial stage . It was unification by diffusion and degradation at later stage. Keywo rds :Carboplatin; Microspheres; Drug. releasing; Mechanism 6超声引导下胎儿脐静脉和心脏穿刺术在产前诊断中的应用 罗 红 周 容 刘之英 （四川大学华西第二医院超声科 610041 E-mail:） 摘 要 目的 探讨超声引导下胎儿 脐静脉和心脏穿刺术在产前 诊断中的价值。 方法 对 78 例因各种原因行产 前诊断的孕妇进行超声引导下脐静脉穿刺术和胎儿心脏穿刺术。结果 脐静脉穿刺成功率 94.03%，胎儿心 脏穿 刺成功率 100%。经胎盘穿刺 36 例，胎盘渗血占 27.8%（10/36），经脐带穿刺 67 例， 脐带渗血占 26.9%（18/67），渗 血均在 30 秒内自动停止。脐静脉穿刺 过程中出现胎儿心动过缓者占 5.97%（4/67）。脐静脉穿刺术后未出现宫内感 染、晚期流产、早产、胎死宫内等并发症。结论 超声引导下胎儿脐静脉是 产前诊断中一项安全、有效的方法。 关键词 超声引导；胎儿脐静脉穿刺术；胎儿心脏穿刺术；产前诊断 Application of ultrasonic guided cordocentesis and fetal cardiocentesis in prenatal diagnosis Luo Hong，Zhou Rong ，Liu Zi-ying. (Department of Ultrasound, West China Second University Hospital of Sichuan University, Chengdu 610041，China.) Abstract Objective To explore the value of ultrasonic guided cordocentesis and fetal cardiocentesis in prenatal diagnosis. Methods Umbilical cords or fatal hearts were punctured under ultrasonic guided in 78 pregnancy women for prenatal diagnosis. Results Success rate of cordocentesis was 94.03%. success rate of fetus cardiocentesis was 100%. There were 36 cases of cordocentesis via placenta, 27.8% of which had placenta errhysis(10/36), and there were 67 cases of cordocentesis, 26.9% of which had cord errhysis (18/67). All the errhysis stopped within 30 seconds automatically. During cordocentesis, 5.97%(4/67) produced bradycardia. There was no intrauterine infection, terminal abortion, preterm delivery, or intrauterine fetal death after cordocentesis. Conclusion Ultrasonic guided cordocentesis is a safe and effective way for prenatal diagnosis. Key words Ultrasonic guided; cordocentesis; cardiocentesis ;prenatal diagnosis 7二维灰阶斑点跟踪功能成像在心脏电生理中的应用 罗安果 尹立雪 （四川省人民医院超声医学中心 成都 610072） 摘 要：二维灰阶斑点跟踪成像（Speckle Tracking Imaging,STI）是一种 观测组织运动的超声新技术，其将追踪 组织声像图中的斑点信号以色彩、曲 线方式选择性地成像。本文就目前该技术在心脏电生理方面的应用作一综述， 主要包括以下内容：识别激动起源点，观测心肌激动传导方向和顺序，观测房颤的心脏电生理状态，观测心脏运动 的同步性，测量电 机械偶联时间 。 关键词：超声，斑点跟踪，心电生理 Clinical Significance of Two-Dimensional Ultrasound Speckle Tracking Imaging in Intracardial Cardiac Electrophysiology LUO An-guo, YIN Li-xue Echocardiography Laboratory, Sichuan Provincial Hospital, Chengdu 610072 Abstract Two-dimensional speckle tracking imaging is a new ultrasound techniques for tracking the speckle signal in tissue image with the advent of color and curve-mode echocardiography, which has made a breakthrough in its observing of cardiac tissue motion,we review the application of recent cardiac electrophysiology with this techniques,which included,to discern the onset of myocardial excitement , to observe the direction and sequence of myocardial conduction, to detect the chronisation of cardiac motion, to observe the cardiac electrophysiology of atrial fibrillation, to measure the delay of electro-mechanics coupling. Key words: Ultrasound;speckle tracking imaging; cardiac electrophysiology 8肺静脉畸形引流的超声诊断 白文娟 唐红 解俊敏 （四川大学华西医院心内科 四川成都 610041） 【摘 要】 肺静脉畸形引流（APVC）系胚胎发育异常导致的先天畸形，是指一支或者多支肺静脉未能直接与左心房 相通，而是直接或间接通过体循环 回流入右房。病理分 为两型：完全型和部分型。解剖分为四型：心上型，心内型， 心下型，混合型。APVC 的病理生理学 类似心房水平左向右分流。大多数 APVC 患者伴有房间隔缺损或室间隔缺 损，在房水平又产 生右向左分流。根据血流动力学可分为：无梗阻型和梗阻型。超声心动图诊断 APVC 的关键在 于多切面扫查。心上型注意胸骨上 窝探查，心内型注意胸骨旁左室 长轴 切面扫查，心下型注意剑下切面的扫查， 混合型检查中应注意寻找四根肺静脉开口及引流的途径，全面扫查。 【关 键 词 】先天性心脏病；超声心动描记术；肺静脉畸形引流 Diagnose of Anomalous Pulmonary Venous Connection by Using Echocardiograhy Bai Wenjuan,Tang Hong,Xie Junming （Department of Cardiology, West China Hospital of Sichuan University, Chengdu, 610041） Abstract: Anomalous pulmonary venous connection（APVC） is a congenital malformation, it means one or more pulmonary vein failed to connect with left atrium, but direct or indirect connect with right atrium.It can divided total and partial types in pathology; 4 types in anatomy, include supracardiac, intra-cardiac, infracardiac, mixed type. The pathophysiology of APVC is similar to atrial septal defect. Most of the suffers companied atrial septal defect or ventricular septal defect. We divided the APVC into non-obstruction and obstruction types according to its hemodynamics. The key of APVC diagnosis is multi-planes check. In the supracardiac type we should attend the suprasternal imaging planes, the intra-cardiac type attend the parasternal long axis view, the infracardiac type attend the subcostal imaging planes, the mixed type attend the 4 pulmonary vein drain path. Keywords: congenital heart disease, echocardiography, anomalous pulmonary venous connection 9超声造影在心脏瓣膜置换术前筛查冠心病的初步研究 解俊敏 1 唐红 1 张尔永 2 彭勇 2 王芳 1 白文娟 1 （四川大学华西医院心内科，1.心内科 2.胸外科 四川成都，610041） 摘要 目的 研究心肌超声造影（myocardial contrast echocardiography,MCE）用于心脏瓣膜病患者术前筛查合并冠 心病（coronary artery disease,CAD ）的可行性及准确性。 方法 对 16例中老年心脏瓣膜病患者行MCE 检查。以冠状动脉造影 (coronary angiography,CAG)作为参考标准 进行分组，观察指 标包括：A、 和A值，建立ROC曲线并计算敏感性及特异性。 结果 A预测中老年瓣膜病合并 CAD 的 ROC 曲线， 曲线下面 积为 0.70，以 A值2.12 预测其敏感性 71.0,特异性 60.9。将 CAG 结 果阴性者， 按照瓣膜病变累及部位分组比较， A、A值均无统计学差异， p0.05。 结论 与 CAG 相比较，MCE 定量分析有较高的敏感性及特异性，可以作为中老年瓣膜病合并 CAD 的术前 筛查手段。 关键词 超声心动图描记术 心肌超声造影 心脏瓣膜病 冠心病 Quantitative Myocardial Contrast Echocardiography for detecting coronary artery disease combined with valvular heart disease Junmin Xie,Hong Tang,Eryong Zhang,Yong Peng,Fang Wang,Wenjuan Bai (Department of Cardiology, West China Hospital of Sichuan University Chengdu 610041) Abstract: Objective The aim of this study is to compare the diagnostic value of myocardial contrast echocardiography (MCE) in coronary artery disease(CAD) with coronary angiography(CAG)during the screening process.Methods 16 patients presenting to hospital with years valvular heart disease were included in the study.They were all performed MCE and CAG or 99mTc MIBI SPECT.Three parameters were A, and A.The LV segments were divided into observation group and control group based on the results of CAG.Receiver operating characteristic (ROC) was drawn and the sensitivity and specificity were calculatedResult A was significant difference between the observation group and the control group.The area under the curve (AUC) of ROC was 0.70.Fo r patients with valvular heart disease,A 2.12 predicts CAD with the sensitivity of 71.0% and specificity of 60.9%.No significantly difference was found among different types of valvular heart diseases with normal results of CAGConclusions Comparing MCE with CAG, quantitative analysis has a good result of sensitivity and specificity .It can be used to detect CAD in patients who combined with valvular heart disease. Key Words: echocardiography, myocardial contrast echocardiography,valvular heart disease,coronary artery disease. 10人工瓣膜置换术后并发症及其超声诊断 延东娥 唐红 1 （四川大学华西医院心内科，四川 成都 610041） 摘要：人工瓣膜置换术是治疗瓣膜性心脏病的有效方法。超声心 动图能无创和准确评价人工瓣膜功能及术后并 发症。本文主要阐 述人工瓣膜置换术 后常见的并发症及其超声表现，旨在 说明超声心动图对检出人工瓣膜置换术 后并发症的重要意义，此外还提到了人工瓣膜的 结构、种 类及血流动 力学特点等相关内容。 关键词：人工瓣膜置换术；并发症；超声心动图 Echocardiography of complication after prosthetic valve replacement Donge Yan Hong Tang （Department of Cardiology, West China Hospital of Sichuan University, Chengdu, 610041） Abstract: prosthetic valve replacement is an effective way to cure valvular heart disease. Echocardiography is able to evaluate the function of prosthetic valve and complications after operation. The article aims to express that echocardiography plays an essential role in detecting complications after prosthetic valve replacement through displaying the frequent complications and its ultrasonic appearance. In addition, we refer to prosthetic valves structure, category and hemodynamics. Key words: prosthetic valve replacement; complication; echocardiography 11速度向量成像对正常左室壁加速度的初步研究 朱霆 张海滨 张军 周晓东 李军 （陕西西安长乐西路 15 号，西京医院超声科 710032 zhuting） 【摘要】 目的 尝试应用速度向量成像（velocity vector imaging，VVI）技术研究正常左室壁加速度特点。 方法 应用 VVI 技术检测 30 例健康志愿者左室 16 个节段运动速度并推演出加速度。结果 同一室壁收缩早期正向峰 值加速度 ACCs (acceleration)和舒 张早期负向峰值加速度 ACCd 表现为基底 中部 心尖（均 P 0.05），同一节段 ACCd显著大于 ACCs（P 0.05）。结论 VVI 技术 可研究室壁加速度特点。 【关键词】 超声心动图，速度向量成像，心肌加速度 Preliminary study on Myocardial acceleration rate of normal left ventricle detected by velocity vector imaging Zhu Ting Zhang Haibin Zhang Jun Zhou Xiaodong Li Jun Department of Ultrasound， Xijing Hospital， Xian 710032 Abstract: Objective To explore the characteristics of segmental myocardial acceleration rate of normal left ventricle (LV). Methods Velocity vector imaging (VVI) was performed in each of the sixteen segments of LV walls in thirty normal volunteers. Segmental myocardial acceleration rate(ACC) was derived from velocity by VVI. Results There were no significant differences among six LV walls of the same level in the early systolic ACCs and early diastolic peak ACCd. However, ACCs and ACCd increased from apex toward base (P 0.05) in the same LV wall. ACCd was significantly higher than ACCs in the same segment (P 0.05). Conclusions Myocardial ACC of the normal LV as detected by VVI can be used for further investigation of diseased myocardial in the present study. Keywords: Echocardiography, Velocity vector imaging, Myocardial acceleration rate 12 1经胸超声心动图对主动脉窦瘤破裂封堵的应用指导 李军 1 张军 1 朱霆 1 张海滨 1 苏军芳 1 薛洁 1 戴政学 2 （西安市西京医院超声科 1，心血管内科 2 西安市长乐西路 15 号 ，zhuting, 710032） 摘 要 目的 探讨超声心动图在主动脉窦瘤破裂封堵术中的应用。方法 2 例单纯主动脉窦瘤破裂入右房患者， 应用超声心动图经导管封堵术前观察窦瘤破口位置、大小、与周围结构的关系及有无合并其他畸形，术中定位和 指导封堵器释放，术后评估疗效和随 访观察。 结果 2 例患者成功封堵。超声心动图术前判断手术适应证准确，术 中正确指导封堵器释放，术后评估效果 满意。 结论 超声心动图是主 动脉窦瘤破裂经导管封堵术前筛选、 术中指 导和术后随访的重要手段。 关键词 超声心动描记术 主动脉窦瘤破裂 封堵 Application of Echocardiography on Occlusion of Ruptured Valsalva Sinus Aneurysm Li Jun，Zhang Jun，Zhu Ting ，et al （Department of Ultrasound，Xijing Hospital，Shannxi，Xian 710032 China ） Abstract：Objective To evaluate the application of echocardiography on transcatheter occlusion of ruptured Valsalva sinus aneurysm. Methods Two patients with Valsalva sinus aneurysm rupturing into right atrium entered the study. Size, location, relationship with neighboring structures of crevasse in aneurysm and complicated malformations were observed before transcatheter occlusion operation, location and release of occluder were instructed during operation, and results of occlusion were evaluated after operation by echocardiography. Results Ruptured Valsalva sinus aneurysms were successfully occluded. Indication of interventional treatment was rightly identified preoperatively, 1基金项目：陕西省科技攻关项目 2005K12-G5(14) occluder relea