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Avian influenza known informally as avian flu or bird flu refers to “influenza caused by viruses adapted to birds.“The version with the greatest concern is highly pathogenic avian influenza (HPAI). “Bird flu” is a phrase similar to “swine flu,” “dog flu,” “horse flu,” or “human flu” in that it refers to an illness caused by any of many different strains of influenza viruses that have adapted to a specific host. All known viruses that cause influenza in birds belong to the species influenza A virus. All subtypes (but not all strains of all subtypes) of influenza A virus are adapted to birds, which is why for many purposes avian flu virus is the influenza A virus. (Note, however, that the “A“ does not stand for “avian“). HA:Hemagglutinin 红细胞凝集素 NA:Neuraminidase 神经氨酸酶 M2:离子通道蛋白 NP:核蛋白 HA refers to a substance that causes red blood cells to agglutinate (凝集). NA catalyze the hydrolysis(水解) of terminal sialic acid (唾液酸) residues from the newly formed virions and from the host cell receptors. 5 At present 16 HA subtypes have been recognised(H1- H16)and nine NA subtypes (N1-N9)。Each virus has one HA and one NA antigen ,apparently in any combination。all influenza A subtypes in the majority of possible combinations have been isolated from avian species。to date only viruses of H5 and H7 subtype have been shown to cause HPAI in susceptible ,but not all H5 and H7 viruses are virulent。 7 If you suspect you may have come into contact with the influenza A virus, look for the following: Fever cough Muscle aches Sore Throat(咽喉痛) Eye infections Pneumonia(肺炎) Severe respiratory diseases (严重的呼吸道疾病) How to Prevent Getting the Avian Flu 1。 Avoid places that birds frequent. Bird baths,bird feeders, roofs and trees are common places where birds leave droppings or saliva. You may inadvertently infect yourself with avian flu by touching these objects and then touching your mouth. Avoid direct contact with wild birds, as there is no way to tell if these birds are infected with avian flu. 8 2 Wash your hands frequently and thoroughly. Wash your hands in hot water with soap for at least 30 seconds. Pay special attention to the area under your fingernails, and dont neglect your forearms. This method of hand washing gets the virus off your skin. 3 Wear a surgical mask if you are going to the hospital or another place where there have been confirmed avian flu diagnoses. This prevents you from inhaling the virus in the air. 9 4 If you plan to travel, check for avian flu outbreaks in your destination before you go. The World Animal Health Interface Database tracks avian flu outbreaks globally and maintains an accurate map. The WAHID map also shows if an outbreak is ongoing or resolved and if it occurred in the wild or domestically. 5 Avoid antibiotic soaps. They do not h

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