医药产品导论期末总结详解.doc

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九、中药合理应用一、中药不良反应概述呼吸系统出现胸闷、咳嗽、喘息；消化系统恶心呕吐、腹痛、腹泻、肝损害、黄疸等；心血管系统心悸、心动过速、血压降低、心律不齐等；神经系统头痛、失眠，震颤等；血液系统的白细胞减少、血小板减少、出血等；泌尿系统的血尿、蛋白尿等。免疫系统皮肤斑疹、瘙痒、弥漫性出血点等,严重者引起过敏性休克，甚至死亡；1、中草药肾病马兜铃酸具有较强的肾毒性，主要是损害肾小管功能，后期出现尿毒症。长期小剂量服用此类药物，可导致慢性马兜铃酸肾病，严重时可导致肾衰。龙胆泻肝丸致尿毒症事件：同仁堂“龙胆泄肝丸”事件-因其中含有关木通，导致患者出现“马兜铃酸肾”。广防己、青木香、马兜铃、寻骨风、天仙藤和朱砂莲等中