高血压和肥胖课件

Hypertension and Obesity in China,Professors Chen Chunming & Zhao Wenhua (On behalf of the Working Group on Obesity in China, ILSI Focal Point in China), Chinese Center for Disease Control and Prevention, Beijing China,Part I: Hypertension risk at BMI and waist circumference (WC) levels,International Life Science Institute Focal Point in China (ILSI FP-China) established a Working Group on Obesity in China (WGOC) in 2000. WGOC organized a meta analysis on the data from 13 big scale cross-sectional survey since 1990, under a protocol for analysis data collected among 239,972 adults aged 20-70 were included.,Data source and analysis,Analysis on disease risks factors, such as high blood pressure, diabetes including fast blood glucose (FBG), serum cholesterol, HDL-C, triglycerides (TG), in relation to BMI and waist circumference (WC) was carried out. Meta analysis of cohort studies covered 4 data sets with 76,227 adult subjects was done, the end points are total mortality, mortality of coronary heart disease, stroke and cancer, as well as incidences of coronary heart disease events and stroke events. Part of the results is presented here.,The results on the prevalence of hypertension, and clustering of risk factors (high blood pressure, diabetes including fast blood glucose (FBG), serum cholesterol, HDL, triglycerides ) and BMI or waist circumference (WC) was presented as follows.,BMI and high blood pressure,Male,Male,Female,The prevalence of hypertension increased with increasing levels of BMI.,WC and high blood pressure,Male,Female,The prevalence of hypertension increased with increasing levels of WC,BMI and risk factor clustering,Male,Female,The prevalence of clustering of risk factors increased with increasing levels of BMI.,WC and risk factor clustering,Male,Female,The prevalence of clustering of risk factors increased with increasing levels of WC.,Population attributable risk percent (%) of hypertension at BMI levels Male Female OR* PARP OR PARP BMI 24 3.69 45.9 2.76 38.4 BMI 28 3.17 11.5 2.61 12.7 * Age adjusted,Population attributable risk % of hypertension beyond WC cutoffs OR* PARP Men WC85cm 3.44 41.3 Women WC80cm 3.30 42.8 * Age adjusted,Part II: Correlation analysis of WC、 BMI and blood pressure,Data source and analysis A study was conducted in Anhui and Henan provinces in 1996 by Chen Junshi and Zhao Wenhua. Totally 11,815 rural residents aged 40-79 were surveyed and information included blood pressure, high, weight and waist circumference, diet and blood sample were collected. The relationship between WC、BMI and blood pressure was analyzed.,Correlation analysis of WC、BMI and blood pressure (male),Correlation analysis of WC、BMI and blood pressure (Female),Prevalence(%) of hypertension by BMI group (male),*,BMI,%HP,BMI、WC and Prevalence of Hypertension,Prevalence(%) of hypertension by BMI group (Female),BMI,%HP,*,Prevalence(%) of hypertension by WC group (male),*,Prevalence(%) of hypertension by WC group (Female),*,Combination of BMI and WC in relation to hypertension prevalence,BMI,Combination of BMI and WC in relation to hypertension prevalence (Male),Combination of BMI and WC in relation to hypertension prevalence (Female),BMI,When WC75cm, prevalence of hypertension increased significantly(P0.05).,Hypertension prevalence % at various WC levels with BMI24（male）,*,Hypertension prevalence % at various WC levels with BMI24（female）,*,At BMI 24, WC 80 (male) WC 75 (female), prevalence or hypertension dramatically increased (p0.05 for all groups),Part III: Summary and Conclusion Data indicated application of Combination of BMI and WC will be the best predictor for hypertension risk, recommendation was made to set overweight cutoff at BMI 24; WC85 for men and 80cm for women as normal.,Applying the classification, overweight (BMI24) prevalence is 30-40%, if BMI could be controlled under 24, 38-45% hypertension of