Blood group systems-ISBT血型系统.docx

Blood group systemsISBTSystem nameSystem symbolEpitopeor carrier, notesChromosome001ABOABOCarbohydrate (N-Acetylgalactosamine,galactose). A, B and H antigens mainly elicitIgMantibody reactions, although anti-H is very rare, see theHh antigen system(Bombay phenotype, ISBT #18).9002MNSMNSGPA / GPB (glycophorinsA and B). Main antigens M, N, S, s.4003PP1Glycolipid. Antigen P1.22004Rh(Rhesus)RHProtein. C, c, D, E, e antigens (there is no d antigen; lowercase d indicates the absence of D).1005LutheranLUProtein (member of theimmunoglobulin superfamily). Set of 21 antigens.19006KellKELGlycoprotein. K1can causehemolytic disease of the newborn (anti-Kell), which can be severe.7007LewisLECarbohydrate (fucoseresidue). Main antigens Leaand Leb- associated with tissue ABH antigen secretion.19008DuffyFYProtein (chemokine receptor). Main antigens Fyaand Fyb. Individuals lacking Duffy antigens altogether are immune tomalariacaused byPlasmodium vivaxandPlasmodium knowlesi.1009KidddbMHCProtein (urea transporter). Main antigens Jkaand Jkb.18010DiegoDIGlycoprotein (band 3, AE 1, or anion exchange). Positive blood is found only amongEast AsiansandNative Americans.17011Yt or CartwrightYTProtein (AChE,acetylcholinesterase).7012XGXGGlycoprotein.X013SciannaSCGlycoprotein.1014DombrockDOGlycoprotein (fixed to cell membrane by GPI, orglycosyl-phosphatidyl-inositol).12015ColtonCOAquaporin 1. Main antigens Co(a) and Co(b).7016Landsteiner-WienerLWProtein (member of theimmunoglobulin superfamily).19017Chido/RodgersCH/RGC4A C4B (complement fractions).6018Hh/BombayHCarbohydrate (fucoseresidue).19019KxXKGlycoprotein.X020GerbichGEGPC / GPD (GlycophorinsC and D).2021CromerCROMGlycoprotein (DAF orCD55, regulates complement fractions C3 and C5, attached to the membrane by GPI).1022KnopsKNGlycoprotein (CR1 orCD35, immune complex receptor).1023IndianINGlycoprotein (CD44adhesion function?).11024OkOKGlycoprotein (CD147).19025RaphMER2Transmembrane glycoprotein.11026JMHJMHProtein (fixed to cell membrane by GPI).6027IiIBranched (I) / unbranched (i)polysaccharide.6028GlobosideGLOBGlycolipid. Antigen P.3029GILGILAquaporin 3.9030Rh-associated glycoproteinRHAGRh-associated glycoprotein.6Langereis4LANABCB6.Porphyrintransporter2Junior4JRABCG2. Multi-drug transporter protein4editReferences1. Table of blood group systems. International Society of Blood Transfusion. October 2006. Retrieved 2006-11-14.2. ISBT Committee on Terminology for Red Cell Surface Antigens.Terminology Home Page. Retrieved 2009-02-13.3. Information Courtesy: Indian Red Cross Society, Tamil Nadu Branch.4. abHelias V, Saison C, Ballif BA, Peyrard T, Takahashi J, Takahashi H, Tanaka M, Deybach J-C, Puy H, le Gall M, Sureau C, Pham B-N, le Pennec P-Y, Tani Y, Cartron J-P, Arnaud L (2012) ABCB6 is dispensable for erythropoiesis and specifies the new blood group system Langereis. Nature Genetics 44 (2): 170 DOI: 10.1038/ng.1069External links ISBT Table of blood group antigens within systemsUpdated August 2008. BGMUTBlood Group Antigen Gene Mutation DatabaseatNCBI,NIH. Blood Groups and Red Cell Antigen