IgA肾病论文自拟肾炎汤治疗IgA肾病气阴两虚夹湿热证的.doc

IgA肾病论文：自拟肾炎汤治疗IgA肾病气阴两虚夹湿热证的临床观察【中文摘要】观察自拟肾炎汤对IgA肾病(IgA nephropathy, IgAN)气阴两虚(夹湿热)证患者尿沉渣红细胞计数、尿微量白蛋白/肌酐比值、24h尿蛋白定量、血清IgA、补体C3及中医证候积分的影响。材料与方法：选择不同程度蛋白尿、血尿的IgA肾病患者60例,随机分为对照组(30例)和治疗组(30例),对照组给予(贝那普利+西医常规)治疗,治疗组在上述治疗的基础上加服自拟肾炎汤,两组共治疗3个月。观察两组治疗前后尿沉渣红细胞计数、尿微量白蛋白/肌酐比值、24h尿蛋白定量、血清IgA、补体C3及中医证候积分的变化情况。结果：(1)自拟肾炎汤对尿沉渣红细胞计数的影响：治疗组能够明显降低尿沉渣红细胞计数,治疗组疗效优于对照组,具有统计学意义(P0.05)。(3)自拟肾炎汤对血清IgA、补体C3的影响：两组治疗前后无明显变化,治疗后组间比较差异无统计学意义(P0.05)。(4)自拟肾炎汤对中医证候积分的影响：治疗组治疗后少气乏力、口干咽燥、手足心热、腰酸腰痛、浮肿症状改善明显,对照组仅在腰酸腰痛、浮肿症状方面有改善,均具有统计学意义(P0.05)。治疗后组间比较：治疗组在少气乏力、口干咽燥、手足心热症状改善方面明显优于对照组,具有统计学意义(P0.05)。(5)在总有效率上,治疗组疗效优于对照组,具有统计学意义(P0.05). (4) Zini Shenyan decoction on the treatment of the clinical symptom score of TCM:The TCM symptoms had been distinctly improved after treatment in the two groups. There was distinctive difference between the two groups, and the treatment group was better than the control group(P0.05). (5) The clinical effects of treatment group was obviously superior to those of contrast group(P0.05).Conclusion:Zini Shenyan decoction can remarkably reduce the urine erythrocyte count and urinary albumin/creatinine and urine protein of 24 hours,so it can reduce the damage of kidney and delay the deterioration of kidney disease.It also can improve clinical symptoms of the patients and improve their quality of life.【关键词】IgA肾病 自拟肾炎汤 尿沉渣红细胞 蛋白尿【英文关键词】IgA nephropathy Zini Shenyan decoction urine erythrocyte count proteinuria【目录】自拟肾炎汤治疗IgA肾病气阴两虚夹湿热证的临床观察中文摘要4-5英文摘要5前言7-8材料与方法8-11结果11-14分析