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HomePathogenesisSymptomsTreatmentNews Tuberculosis ThisisawarofMycobacteriumtuberculosisandtheimmunesystem Question1Whoistheundefeatedworldchampion 2Whatistheworldchampion ssecretweaponforkillingallhisenemies 3Whatcanwedotodefendhim Whydidhecamebackinth21stcentury 5Canyouremembersomeotherinformation Ifyouhavebeencoughingforevenjusthadalotofphlegmsforovertwoweeks don tfeelembarrassedgotothehospital back Mycobacteriumtuberculosis M tuberculosis commonlyknownasMycobacteriumtuberculosis thepathogenthatcausetuberculosis Violationsofbodyorgans buttuberculosisisthemostcommon Tuberculosissofarisstillanimportantinfectiousdisease Estimated1 3oftheworld spopulationinfectedwithMycobacteriumtuberculosis AccordingtotheWHOreport about8millionnewcasesoccureachyear atleast300millionpeoplediedofthedisease InChinabeforethefoundingofmortalityupto200 300 100000 thecauseofdeathinavarietyofdiseases Bacterium back Pathogenesis back symptoms 1chroniconset Mainlyfatigue fever weightlossandothersymptoms2withacuteonset Moderatefeverorhighfever cough coughsmallamountofsputum3hemoptysisonset Ranginghemoptysisorsputum blood hemoptysisoftencausethepatient sattentionforchestorchestradiography andfurtherforsputumexaminationandtuberculosis 4 thesicksideofthechestpain fever shortnessofbreathandothersymptoms Checkthefoundpleurisy back Thestoryofthreemenwiththedisease Treatment 1 Drug resistantTuberculosis Drug resistantTBiscausedbyTBbacteriathatareresistanttoatleastonefirst lineanti TBdrug Multidrug resistantTB MDRTB isresistanttomorethanoneanti TBdrugandatleastisoniazid INH andrifampin RIF 2 LatentTBInfection ThemedicationsusedtotreatlatentTBinfectioninclude isoniazid INH 异烟肼 rifampin RIF 利福平 rifapentine RPT 利福喷丁 Certaingroupsofpeople suchaspeoplewithweakenedimmunesystems areatveryhighriskofdevelopingTBdiseaseonceinfectedwithTBbacteria EveryeffortshouldbemadetobeginappropriatetreatmentandtoensurecompletionoftheentirecourseoftreatmentforlatentTBinfection 3 TBDisease Thecontinuationphaseoftreatmentisgivenforeither4or7months The4 monthcontinuationphaseshouldbeusedinthelargemajorityofpatients back Healthcare 1 Administrativemeasures2 Environmentalcontrols3 UseofrespiratoryprotectiveequipmentThefirstandmostimportantlevelofthehierarchy administrativemeasures impactsthelargestnumberofpeople ItisintendedprimarilytoreducetheriskofuninfectedpeoplewhoareexposedtopeoplewhohaveTBdisease ThesecondlevelofthehierarchyistheuseofenvironmentalcontrolstoreducetheamountofTBintheair ThefirsttwocontrollevelsofthehierarchyalsominimizethenumberofareasinthehealthcaresettingwhereexposuretoTBmayoccur ThethirdlevelofthehierarchyistheuseofrespiratoryprotectiveequipmentinsituationsthatposeahighriskofexposuretoTB Useofrespiratoryprotectionequipmentcanfurtherreducetheriskforexposureofhealthcareworkers back News back Epidemicsituation Afterseveralyearsofjointeffortsworldwide theglobaltuberculosisepidemictrendappearsnewchange Bytheendof2011whoannouncedaglobalsignificantnewfindings 1 since2006 theabsolutenumberofcasesoftuberculosisdeclined asopposedtoaglobalreportontheslowrise 2 since2002 oftuberculosisincidencedecreased thismorethanevertheincidencebegantodeclinein2010 twoyearsearlier estimatingtheglobalnewtuberculosispatients areportof8800000cases 3 reducedtheannualTBdeathsestimatednumber 2010notinfectedwiththeAIDSvirusto

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