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CURRICULUM VITAE M D Ph D Address Department of Neurology l Hospital Beijing P R China Phone E mail Research objectives Vascular pathology in stroke Genetic research in CMT Functional MR in stroke Intra arterial venous thrombolysis in acute cerebral infarction CAREER AIMS Short term To procure a post doctoral vacancy abroad for 1 or 2 years to broaden my view to enhance my skills and to acquire the ability to meet the requirement of higher standard of work My interests are Pathology in AD and VaD Genetic research in CMT and CADASIL Functional MR in Stroke Long term To cooperate with more experts and became more and more expert in Neurological research EDUCATION 2003 2006 Ph D in Neurology The University Chongqing P R China Thesis Advisor Prof In this study I 2000 2003 M S studies in Neurology The University Chongqing P R China Thesis Advisor Prof This project is to analysis 1995 2000 M D in clinical medicine The University Chongqing P R China APPOINTMENTS 01 2009 Present Chief Resident Department of Neurology Hospital 10 2007 Present Instructor Physician in charge Department of Neurology Hospital 10 2000 10 2007 Physician resident Department of Neurology Hospital HONORS AND AWARDS 2007 Excellent Physician resident Hospital 2010 Excellent Chief Resident Beijing Military General Hospital RESEARCH EXPERIENCE Principal in a project supported by the National Science Foundation of China Grant 30800357 This project which will be finished in July 2011 is to study the relationship between phenotype switch of VSMC and Notch3 Main participator in a project supported by National Science Foundation of China Grant 30470609 In this project I have found when the FLNmRNA in VSMC was suppressed by RNAi the proliferation of VSMC was descended and the switch from Contractil phenotype to Synthetic phenotype was blocked This result will be published in Cell Biochemistry and Biophysics IF 4 37 in a few months I have found a huge family 250 persons family tree is in appendix of CMT but the mutation cann t be identified with common method Now we use whole exon sequencing to identifies the mutations and the result will came out in a few weeks I also am familiar with the protocol of clinic trial and attend in some international clinic trials These include PROFESS Prevention Regimen for Effectively Avoiding Second Strokes INTERACT Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial ESPRIT European stroke prevention in reversible ischemia trial CASTA Cerebrolysin in patients with Acute ischemic Stroke in Asia and et al Now I am the member of the Ethic committee in my hospital SELECTED PUBLICATIONS PROFESSIONAL AFFILIATIONS LABORATORY SKILLS Intensive experience in Neuropathology and neuroimaging In 2001 Study the method of Neuropathology under the Prof Mageritta for 6 months She was a neurologist in Dept Neuropathology UPSALA university Sweden In the period I learned the method of pathology and neuropathology include of Immunohistochemistry Immunofluorescence in situ hybridization and so on In 2003 take part in a neuropathology training course hold by the neuropathological branch of CMA for one month In 2005 and 2009 take part in the advanced neuropathology training courses for half a month each time After these courses I learned the pathological diagnosis of many neurological diseases In 2009 take part in the neuroimaging training course hold by neuroimaging branch of CMA for 3 months This course was to study the MRI diagnosis of neurological disease which include of cerebral vascular disease cerebral tumor and Degeneration I can read cerebral or spinal CT scans or MR scans and make the diagnosis independently I am familiar with the imaging changes of cerebral infarction cerebral hemorrhage MS cerebral infectious disease and cerebral tumors In my clinical practice I have diagnosed many intractable cases by myself which include of reversible posterior leukoencephalopathy syndrome RPLES Wernicke s encephalopathy Cerebral Venous Thrombosis progressive supranuclear palsy PSP Creutzfeldt Jakob disease CJD cavernous malformation central pontine myelinolysis CPM extra pontine myelinolysis EPM gliomatosis cerebri primary central nervous system lymphoma PCNSL Tolosa Hunt syndrome multiple system atrophy MSA mitochondrial myopathy and so on From 2006 to now I study the MR change and genetic mutation of CADASIL I had got more than 10 families of CADASIL More than 50 persons in these families were detected the mutation of gene or some change in MR imaging The article will be finished in no more than one year Familiar with common molecular biology technology including PCR and RT PaCR SSCP RFLP genotyping primer and probe design plasmid preparation Liposome
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