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120AA复方氨基酸注射液细菌内毒素检查法的实验研究A1A0A0A3A3A4A2A4A2A5A620AAA7A8A9A10A11A12A13A14A15A16A17A18A19A20A21A22A23A24A25A26A27A28A29A30A31A32A33A16A17A18A19A20A25A34A35A21A22A8A36A37A38A39A40A41A42A43A44A45A46A472005A48A49A50A51A52A53A54A55A56A57A58A59A60A61A62A63A64A65A66A67A68A69A70A71A72A73A74A75A76A77A78A72A73A79A80A81A82A83A84A85A86A79A87A83A88A66A67A89A90A83A69A91A92A93A94A9520AAA96A97A98A99A100A101A102A103A1044A105A106A107A108A109A110A111A112A113A114A115A116A117A118A119A118A119A120A121A122A123A124A125A126A127A128A129A130A131A132A133A134A135A136A137A138A130A131A132A139A121A140A141A142A143A144A145A127A128A129A146A147A148A149MLA150A127A128A129A143A151A152A15312EUA154A155A156A15720AAA158A159A160A161A162A163A164A165A166A125A126A127A128A129A167A168A146A143A130A131A132A166A169A170A171A172STUDYONBACTERIALENDOTOXINTESTMETHODFOR20AACOMPOUNDAMINOACIDINJECTIONABSTRACTA173AIMTOSTUDYTHEINTERFERENCEOF20AACOMPOUNDAMINOACIDINJECTIONINBACTERIALENDOTOXINTEST,ANDTOESTABLISHAMETHODOFENDOTOXINLIMITTESTFORTHEPREPARATIONMETHODSTHEBACTERIALENDOTOXINTESTISPERFORMEDACCORDINGTOTHEBACTERIALENDOTOXINDETERMINATIONMETHODINCHINAPHARMACOPOEIA2005,USINGDIFFERENTTACHYPLEUSAMEBOCYTELYSATETALMADEINMOREMANUFACTURERSRESULTSINFOURTIMESDILUTEDCONCENTRATION,THE20AACOMPOUNDAMINOACIDINJECTIONDIDNOTINTERFEREINTHERESULTOFTHETESTCONCLUSIONINPLACEOFRABBITPYROGENMETHOD,THEGELCLOTTESTOFBACTERIALENDOTOXINCOULDBEUSEDFORCONTROLTHEQUALITYOF20AACOMPOUNDAMINOACIDINJECTION,INWHICHTHEBACTERIALENDOTOXINLIMITSHOULDBELESSTHAN12EUML1KEYWORDS20AACOMPOUNDAMINOACIDINJECTIONA174GELCLOTTESTMETHODOFBACTERIALENDOTOXINA174INTERFERENCETESTA175A176A177A178A179A180A181A182A183A184A185A186A187A188A189A190A191A192A187A193A194A195A196A197A198A199A200A201A202A203A204A205A206A177A178A179A199A207A208A200A209A210A211A212A213A192A214A215A216A217A218A219A220A221A187A222A223A224A188A189A225A226A177A178A179A227A228A214A199A229A190A230A231A2326A227A177A178A179A2336AAA234A20113A227A177A178A179A23313AAA234A20118A227A177A178A179A23318AAA234A206A235A227A175A176A177A178A179A180A181A182A217A236A185A218A219A220A221A213A192A237A238A239A240A241A188A242A22620A227A177A178A179A214A175A176A177A178A179A180A181A182A233A243A24420AAA234A190A245A246A247A248A209A210A249A175A190A250A251A252A253A254A255A190A150DNAA151A0A1A253A206A176A2A3A4A5A6A190A183A236A185A95A7A8A9A10A11A12A13A167A14A214A15A192A188A189A217A88A16A17A232A4A18A19A18820AAA57A20A21A22A26A172A23A24A25A36A37A27A28A29A412005A42A30A31A45A32A33A34A35A38A39A40A43A44A461A50A47A48A49A51A52A53A54A26A176A55A56A34A35A38A39A40A43A44A46A58A59A60A61A43A44A46A62A9320AAA63A64A65A66A67A68A69A70A21A22A71A72A73A74A47A75A26A58A178A76A77A78A73A79A80A811A82A83A84A85A86A87A89A82A83A84A85A87A89ZH2A185A90A91A92A94A96A97A130A191A98A99A100A101A102A103A97A104A131A105BETA106A107A108A109A110A111A112A103A130A191A98A99A100A101A102A103A97A104A113A114A196A115A116A117A118A119A198A120A121A118A122A123A124250A201A125A1261HA127A128A129A132A133A114A134A135A136A137A138A139A140A141A142A143A144CSEA113A145A146A14720056A148100EUA1651A144A149A152A153A143A154A155A156A143A157A1582A196A113A159A160A117A161A144TALA113A145A141A193A162A163A120A144A212A113A164025EUML1A148A146A1470701040A1190506312A148A144A213A166A168A120A199A154A155A169A170A171A173A113A159A160A117A161A144TALA113A145A141A193A162A163A120A144A212A113A164025EUML1A148A146A1470703071A1190603240A148A144A213A166A174A175A177A179A154A155A169A170A171A173A113A134A135A136A137A138A157A180A115A181A144WBETA113A145A222A18210MLA1651A148A146A147070525A148A144A213A166A174A175A177A179A154A155A169A170A171A173A113A11420AAA145A146A147A183A184A164061226A119070507A119070614A148A222A182250MLA144A186A187A156A161A188A189A156A148A190A192A132A133A157A180A194A123A195A197A222A158A113A1142A200A202A203A204A205A202A203A204A2052A2061A207A208A209A210A211A214A215A216A217A218A219A220A230A221A223A224A225A226A227A2282005A229A231A232A233A207A208A209A210A211A214A219A220A208A234A235A236A237A238A239A240A241A242A243A244A245A246A247A248A249A250A2510520A249A252A253A238A254A255A228A0A1A332A212A12A2A3A4A5A6A7A248LA250A8A9A101A119A11A13A14A151A16LK/MA235A17A18A19A20A8A22A23A24A25A26A27A10A208A28A29A14A234KA88A30A31A10A8A32A34A35A36A37A38A39KGA114A40A39HA240A41A42A43A44A8A24A25A26A45A46A47A53EUKG1H1A244A48A29A49A50A45A8KA8850EUKG1H1A94A14A234MA88A37A38A39KGA114A40A39HA240A41A18A19A20A38A46A47A53MLKG1H1A244A48A2920AAA121A51A240A41A38A46A88A39A52250MLA47A2461HA247A54A55A49A56A47A37A239A114A40A3060KGA235A17A47A251M250ML/60KGH142MLKG1H1A29A252A57A58KA60MA254A28A59A37A13A14A611A62A234A47A251LK/M50EUKG1H1/42MLKG1H112EUML1A29A63A64A9A1020AAA8A22A23A24A25A26A208A28A8812EUML1A292A653A66A67A68A69A70A71A67A72A73A74A75A76A77A78A79A80A81A82A83A84A85A86A87A89A90A91A92A93A77A95A96A97A98A99A100A101A102A103A104A105A106A107A108A109A110A111A112A113A115A116A89A90A91A117A118A120A76A122A123A1242A1253A1251A126A127A128A129A130A131A132A133A134MVDA135A136A137A138A230A139A140A1412A142MVDCL/A212A143A144A145A146A147LA148A149A150A151A152A153A154A155A156A157A158A159A160A161A148A162A150A163A164A150A165A152A166A167A168A169A1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