USP美国药典 液相方法色谱柱汇总

1、USP美国药典 液相方法色谱柱汇总默认分类 2010-02-22 16:50:57 阅读297 评论0 字号：大中小订阅 液色迷人USP即美国药典，为高效液相色谱柱填料规定了一些指标，即USP L1-USP L60系列。用户经常会在文献和技术开发中遇到用符合USP L系列方法的液相柱分离的要求，为此我们在此把我们公司能够提供的符合此方法的液相柱作一列表，供您参考！USP填料描述推荐色谱柱L1C18烷基化学键合于多孔硅胶或陶瓷微粒，3-10uC18: COSMOSIL, Polaris,L2C18烷基化学键合于多孔硅胶，30-50uC18分离填料：FUJI 填料 L3多孔硅胶微粒，5-10uSI

2、L: COSMOSIL, PolarisL4硅胶微粒，30-50uL5氧化铝微粒，30-50uL6强阳离子交换填料：磺化氟碳聚合物涂于固体球形核粒上，30-50u L7C8烷基化学键合于3-10u完全多孔硅胶微粒C8: COSMOSIL, Polaris,L8单分子层丙氨基化学键合于10u硅胶载体，NH2: COSMOSIL, Polaris,L9强酸性阳离子交换基团键合于10u无定形多孔硅胶，SCX:Nucleosil SA; HYPERSILL10氰基化学键合于5-10u多孔硅胶颗粒，CN:COSMOSIL, PolarisL11苯基化学键合于5-10u多孔硅胶颗粒，苯基柱:COSMOSI

3、L,KROMASILL12季铵基化学键合于30-50u固体硅胶小球上，强阴离子交换填料L13三甲基硅烷化学键合于5-10u多孔硅胶颗粒，C1(TMS):COSMOSIL, KROMASILL14带强碱性季铵基的阴离子交换涂料化学键合于10u硅胶微粒，SAX: Nucleosil SB;Hypersil;ZorbaxL15六烷基化学键合于全多孔硅胶颗粒，3-10uC6:Allsphere,ChromegabondL16二甲基化学键合于全多孔硅胶颗粒，5-10uC2:Nucleosil,AdsorbosilL17强阳离子交换树脂：氢型、磺化交联的苯乙烯二乙烯基苯共聚物，7-11uHamilton

4、HC 75氢型柱, PL- Hi-Plex HL18氨基和氰基官能团键合于5-10u的多孔硅胶颗粒上Partsil PACL19强阳离子交换树脂：钙型、磺化交联的苯乙烯二乙烯基苯共聚物，9uHamilton HC 75钙型柱，PL- Hi-Plex CaL20二羟基丙烷基团化学键合于多孔硅胶颗粒，5-10uDiol:NucleosilL21刚性的苯乙烯二乙烯基苯共聚物小球，5-10u PRP-1:Hamilton；PLRP-SL22阳离子交换树脂：带磺酸基团的多孔苯乙烯聚合物小球，外径约10uHamilton PRP-X200, L23阴离子交换树脂：带季铵基团的聚甲基丙烯酸甲酯或聚丙烯酸甲酯

5、多孔胶体，约10u外径TSK-DEAE-5PW, COSMOGEL QAL24基体表面带大量羟基团的聚乙烯构成的半刚性亲水凝胶，32-63u外径L25该填料应能分离分子量从100-5000道尔顿的化合物，用于分离中性，阳离子型及阴离子型的水溶性聚合物。以聚甲基丙烯酸甲酯树脂为载体，交联聚甲氧基乙醚，表面含有残留羰基基团GFC:Macrosphere(7u),Shodex Ohpak SB-802.5L26丁基硅烷化学键合于全多孔硅胶颗粒上，5-10uC4:COSMOSIL, KROMASILL27多孔硅胶颗粒，30-50u外径L28100埃的高纯、球形硅胶键合以阴离子性以及C8基团的多功能载体

6、液色迷人L29氧化铝，反相，含碳率低，氧化铝基的聚丁二烯小球，5u，80埃GammaBond RP1L30乙基硅烷化学键合于多孔硅胶上，3-10u外径C2:Nucleosil,AdsorbosilL31强阴离子交换树脂：季铵基键合于乳胶颗粒上，分散于8.5u大小，孔径2000埃的乙基乙烯基苯和二乙烯基苯（55%）的交连聚合物颗粒中液色迷人L32配位体交换手性填料：L脯氨酸铜共价键合于不规则硅胶颗粒上，5-10uCOSMOSIL CSP-HPR,Nucleosil chiral-1L33能够分离4000-400，000道尔顿的蛋白质，球形硅胶载体，具PH稳定性Nucleosil 125-5 GF

7、C,TSK G3000SWL34强阳离子交换树脂：铅型、磺化交联的苯乙烯二乙烯基苯共聚物，9uHamilton HC 75铅型柱，Hi-Plex Pb L35经锆强化的球形硅胶颗粒，亲水性单分子层键合，孔径150埃Zorbax GF-250L36L苯基甘氨酸的3,5二硝基苯甲酰衍生物共价键合在 5um的氨丙基硅胶上Nucleosil chiral-3 手性柱L37能分离2，00040，000分子量蛋白质的聚甲基丙烯酸凝胶Shodex OHpak SB-803HQ L38分离水溶性样品的甲基丙烯酸机质的体积排阻填料Shodex OHpak SB-802HQL39亲水性 聚羟甲基丙烯酸 全多孔球形

8、树脂Shodex OHpak SB-800系列L403，5二甲苯甲氨酸纤维素涂布在5到20um的多孔硅胶上CHIRALCEL OD; NUCLEOCEL DELTAL41固化ALPHA酸糖蛋白在5um的硅胶颗粒上Chiral-AGP，L42C8和C18烷基化学键合于多孔硅胶微粒，5uL43五氟苯基化学键合在5-10u的硅胶微粒上TAXSIL五氟苯基柱：常做紫杉醇分析用L44A multifunctional support,which consists of a high purity, 60?, spherical silica substrate that has been bonded

9、with a cationic exchanger,sulphonic acid functionality in addition to a conventional reversed-phase C8 functionality.Chromegabond RP-SCXL45Beta cyclodextrin bonded to porous silica particles, 5 to 10um in diameterNUCLEODEX -OH; ChirDexL47High capacity anion exchagne microporous substrate,8um in diam

10、eter,dimension 250 x 4.0mmDionex CarboPac MA1L49A reverse-phase packing made by coating a thin layer of polybutadiene on to a spherical porous zirconia particles, 3 to 10umPBD柱L50A strong cation exchange resin made of porous silica with sulphopropyl groups, 5 to 10um in diameter.TSK IC SWL51Amylose

11、tris-3,5-dimethylphenylcarbamate-coated,porous,spherical,silica particles,5 to 10um in diameterChiralpak AD; NUCLEOCEL ALPHAL52A strong cation-exchange resin made of porous silica with sulphopropyl groups,5 to 10um in diameter.TSKgel IC-Cation , TSKgel SP-2SWL53Weak cation-exchange resin consisting

12、of ethylvinylbenzene,55% cross-linked with divinylbenzene polymer,3 to 15um in diameter.Substrate is surface grafted with carboxylic acid and/or phosphoric acid functionalized monomers.Capacity not less than 500uEq/column.IonPac CS14L54A size exclusion medium made of covalent bonding of dextran to h

13、ighly cross-linked porous agarose beads, about 13um in diameter.Superdex Peptide HR 10/30L55A strong cation-exchange resin made of poroous silica coated with polybutadiene-maleic acid copolymer,about 5um in diameter.L56Propyl silane chemically bonded to totally porous silica particles,3 to 10um in d

14、iameterZorbax SB-C3L57Chiral recognition protein, ucoid, chemically bonded to silica , about 5um, with a pore size of 120AES-OVM手性柱L58Strong cation-exchange resin consisting of sulphonated cross-linked styrene-divinylbenzene copolymer in the sodium form, about 7 to 11um diameterPL Hi-Plex NaL59Packi

15、ng having the capacity to separate proteins by molecular weight over the range of 10 to 500kDa. It is spherical(10um), silica-based,and processed to provide hydrophilic characteristics and pH stabilityTSKgel G3000SWL60Spherical porous silica gel,3 or 5um in diameter, the surface of which has been covalently modified with palmitamidopropyl groups and endcapped.NUCLEOSIL C18 NautilusL61A hydroxide-selective,strong anion-exchange resin consisting of a highly cross-linked core of 13um microporous particles having a pore size less than 10 angstrom and consisting of ethylvinylbenzene cross-lin