宝宝长湿疹的原因及如何处理_图文

1、I喳鏖廛丛型苤蠢垫!垒生箜鲞筮!塑鱼!鱼里!塑!:丛!塑h至Q!垒,y!.箜:盟!.三儿童湿疹872例血清过敏原特异性IgE 检测结果分析陈戟.程颖(上海交通大学医学院附属上海儿童医学中心皮肤科,上海200127148论著【摘要】目的:检测湿疹患儿常见的过敏原,寻找儿童湿疹可能的过敏促发因素,为其治疗及预防提供依据。方法:采用Mediwiss公司Allergyscreen Analytic GmbH过敏原检测系统,对872例湿疹患儿进行血清特异性IgE(specific IgE,sIgE和总IgE检测,并在不同年龄组间进行比较。结果:872例湿疹患儿sIgE阳性690例(79.13%,总IgE

2、阳性709例(81.30%。其中吸人性过敏原最常见的依次为户尘螨(34.60%、点青霉(22.71%、屋尘(16.28%和狗毛皮屑(10.89%;食物性过敏原中,最常见的依次为牛奶(36.12%、羊肉(22.94%、鸡蛋白(20.07%和牛肉(13.88%。比较<1岁组,13岁组和>3岁组,户尘螨、屋尘、狗毛皮屑、点青霉、鸡蛋白、牛奶、羊肉和蟹的sIgE阳性率的差异有统计学意义(P<0.05。结论:户尘螨、点青霉和屋尘是湿疹患儿最主要的吸人性过敏原。牛奶、羊肉、鸡蛋白是湿疹患儿最常见的食物性过敏原。随年龄增大,吸人性过敏原逐步取代食物成为主要过敏原。血清sIgE检测为湿疹患儿

3、提示了相关过敏原,可以针对性地回避相关过敏原。关键词】湿疹;过敏原特异性IgE;血清;儿童中图分类号】R758.24;R4J46.62【文献标识码A【文章编号】10004965(201403014803Amlysis of ser哪枷ergenspecinc IgE in872cllildren耐th eczemaCHEN Ji,CHENG Ying(Dep州脚m0,De珊优Dfo肼胁帆曲面吼i胁ens胁妣甜ce耽r,.scooZ o,胁dic妇,航帆曲缸五fo昭跏面e阳慨鼽吼咖缸2DOJ27,mi加【Abstract】objective:To identify the possible ae

4、rgy triggers via detecting the common allergens in children witIl eczema, pmviding scientmc basis for tlle treatment and prevention ofeczema.Methods:Semm allergenspecific IgE(sIgEand total IgE(tIgEwere detected by Aergy Screen detection system in872children with eczema and were comPared among childr

5、en in di归ferent age gmups.ResllIts:Six hundreds and ninety of872(79.13%children with eczema were positive for sIgE,and 709of872(81.30%weIe positive for tIgE.The common aemaUergens were de瑚atophagoides f;血nae(DF(34.60%,penicillium notatum(22.7l%,house dust(16.28%and dog dander(10.89%;rhe common food

6、allergens were milk(36.12%, mutton(22.94%,egg white(20.07%and beef(13.88%.7Ihe positive rates fbr sIgE of DF,house dust,dog dander,penicillium notatum,egg white,milk,mutton and crab were significant di.erent among children aged<1,13and oVer3years(P< 0.05.Condusions:The major aemallergens are D

7、F,peniciuium notatum and house dust in children with eczema,and the common food allergens are milk,mutton and egg white.Aemaergens are becoming the major allergens as children gettingolder.Semm sIgE tests can identify relevant allergens for patients with eczema to avoid them.【Ke,w跳】eczema;allergensp

8、eci矗c IgE;serum;ch订dJ Clin Dematol,2014,43(3:148150湿疹是儿童常见的慢性、复发性、过敏性皮肤病。其病因非常复杂.除了与遗传因素、皮肤屏障功能缺陷、免疫系统功能失衡有关,外界环境中的过敏原不仅是湿疹的促发因素,也是导致湿疹反复发作的重要原因【1】。血清过敏原特异性IgE检测可以一次性检测多个过敏原.包括吸人性过敏原和食入性过敏原,为临床常用检测方法。本文对872例湿疹患儿的血清特异性IgE(sIgE抗体进行检测,现报告如下。收稿日期:29130311;修回日期:201308101资料与方法1.1资料2010年3月一2012年12月在本院皮肤科门诊就诊的湿疹患儿,诊断符合文献2中湿疹的诊断标准,872例湿疹患儿进行sIgE检测,其中男502例,女370例;年龄6个月一14岁,平均(3.7