医学资料-喉癌tnm分期英文版

1、喉癌 TNM 分期英文版Primary tumor (T)TX: Primary tumor cannot be assessedT0: No evidenee of primary tumorTis: Carcinoma in situSupraglottisT1: Tumor limited to one subsite* of supraglottis with normal voc al cord mobilityT2: Tumor inv ades mucosa of more tha n one adjace nt subsite* o f supraglottisor glott

2、is or region outside the supraglottis (e.g., muc osa of base of tongue, vallecula,or medial wall of pyriform sinus)withoutfixationof thelary nxT3: Tumorlimited tolary nx withvocal cord fixationan d/orinvades anyof thefollowi ng:postcricoidarea, pre-epiglottictissues,paraglotticspace,and/or minor thy

3、roidcartilageerosion (e.g., innercortex)T4a: Tumorinv ades through thethyroidcartilage,and/or invadestissues beyond the larynx (e.g., trachea, soft tissues of the neck in cluding deepextrinsicmuscle of the tongue, strap muscles, thyroid,or esophagus)T4b: Tumor invades prevertebral space, encases car

4、otid artery, o r invadesmediastinal structuresSubsites include the following:Ventricular bands (false cords)Aryte noidsSuprahyoid epiglottisIn frahyoid epiglottisAryepiglottic folds (lary ngeal aspect)Note: Supraglottisinvo Ives many in dividualsubsites. Relapse-free survival may differ by subsite a

5、nd by T and N group ings with in s tage.GlottisT1: Tumor limited to the vocal cord(s), which may invoIve anterio r or posteriorcommissure, with normal mobilityT1a: Tumor limited to one vocal cordT1b: Tumor invoIves both vocal cordsT2: Tumor extends to supraglottis and/or subglottisand/or with impair

6、ed vocal cord mobilityT3: Tumor limited to the larynx with vocal cord fixation and/or in vades paraglotticspace, and/or minor thyroid cartilage erosion (e.g., inner cortex)T4a: Tumor invades through the thyroid cartilage and/or invades tissues beyondthe larynx (e.g., trachea, soft tissues of neck, i

7、nclud ing deep extrinsic muscle of thetongue, strap muscles, thyroid, or esophagus)T4b: Tumor invades prevertebral space, encases carotid artery, o r invadesmediastinalstructuresNote: Glottic prese ntati on may vary by volume of tumor, an atom ic regioninvoIved, and the presenee or absenee of normal

8、 cord mo bility. Relapse-freesurvival may differ by these and other factors in addition to T and N subgroupingswithin the stage.SubglottisT1: Tumor limited to the subglottisT2: Tumor extends to vocal cord(s) with normal or impaired mobi lityT3: Tumor limited to larynx with vocal cord fixationT4a: Tu

9、mor invades cricoid or thyroid cartilage and/or invades tis sues beyond thelarynx (e.g., trachea, soft tissues of neck, includin g deep extrinsic muscles of thetongue, strap muscles, thyroid, or e sophagus)T4b: Tumor invades prevertebral space, encases carotid artery, o r invadesmediastinalstructure

10、sRegi onal lymph no des (N)NX: Regi onal lymph no des cannot be assessedN0: No regional lymph node metastasisN1: Metastasisina singleipsilaterallymph node3 cm or smallerin greatest dimensionN2: Metastasisina singleipsilaterallymph nodelarger than 3 cm but 6 cm or smaller in greatest dimension, or in

11、 multiple ipsilater al lymph no des 6cm or smaller in greatest dime nsion, or in bilater al or con tralateral lymph no des 6cm or smaller in greatest dime nsi onN2a: Metastasis in a single ipsilateral lymph node larger than 3 c m but 6 cm orsmaller in greatest dimensionN2b: Metastasis in multiple ip

12、silateral lymph no des 6 cm or smal ler in greatestdimensionN2c: Metastasis in bilateral or con tralaterallymph no des 6 cm orsmaller in greatest dimensionN3: Metastasis in a lymph node larger than 6 cm in greatest dim ensionIn cli ni cal evaluati on, the actual size of the no dal mass should b e me

13、asured,and allowanee should be made for intervening soft tissues. Most masses larger than 3 cm in diameter are not single node s but con flue ntno des or tumors in soft tissues of the n eck. There are three stages of cli ni callypositive no des: N1, N2, and N3. The u se of subgroups a, b, and c is not required butrecommended. Midl ine no des are con sidered homolateral no des.Dista nt metastasis (M)MX: Distant metastasiscannot be assessedMO: No distant metastasisM1: Distant metastasisAJCC Stage GroupingsStage 0Tis, NO, MO