老年晚期胃癌论文：老年晚期胃癌健脾养胃,解毒祛瘀法卡培他滨临床研究

1、培他滨临床研究【中文摘要】观察胃癌I号方联合化学治疗对老年晚期胃癌患者生活质量的影响，初步评价胃癌I号方临床治疗老年晚期胃癌中的地位,并为其推广并应用于老年晚期胃癌提供临床依据。方法：采用随机对照的方法，对47例老年晚期胃癌患者，随机分为2组,其中治疗组（胃癌I号方联合卡培他滨单药方案化疗）23例、对照组（单纯卡培他滨单药方案化疗）24例。以21天为1个周期,连续观察2周期。治疗组在化疗的同时给予胃癌I号方水煎服，每日1齐叽比较两组患者在客观疗效、生活质量及中医症状等方面的情况。结果：客观疗效比较：两组比较无显著差异（p>0.05）。生活质量比较：治疗组生活质量明显优于对照组（p0.05

2、）,治疗后治疗组疗效明显高于对照组治疗组（p0.05）。结论：胃癌I号方联合卡培他滨单药方案化疗可以明显提高老年晚期胃患者的生活质量，改善中医临床症状；老年晚期肿瘤的治疗是需要多种治疗手段综合治疗的，中医药和化疗的有机结合可以显著改善患者的生活质量。【英文摘要】：Observedtheimpactoftheadvaneedgastriccaneers'qualityoflife,whotherapyofWeiAi-1-PrescriptionjointCapecitabine,Assessmentofitsstatusandadvantages,andthenprovideascien

3、tificbasisforitsclinicalapplicationandfurtherresearches.Method:AIIthepatientsarefromtheChineseMedicineHospitalofChangzhouCity.Theyareacceptedbystrictstandardsaccordingtotheresearch.The47acceptedcasesaredividedintotwogroups,thetreatmentgroupwith24casesandthecontrolgroupwith23cases.Thetreatmentgroupar

4、etreatedbyWeiAi-1-PrescriptionjointCapecitabine,thecontrolgrouparetreatedbyCapecitabine,thecourseofthetreatmentlastsfor42days.Thenthesizeofthetumor、qualityoflife、TCgointsandhand-footsyndromearemeasuredinallthecasesbeforeandafterthetreatment.Atlast,analyzetheefficacyandthesafetyofthetwo'therapies

5、withallthesedata.Results:lnthesizeofthetumor,thechangeofitisnotwithsignification(p>0.05);lnthequalityoflife,thetreatmentgroupismoreobviousthanthatinthecontrolgroup(p<0.05);IntheTCMpoints,inthetreatmentgroup,5casesmarkedly,16casesofeffective,theoverallresponseratewas91.30%,inthecontrolgroup,2ca

6、sesmarkedly,4casesofeffective,theoverallresponseratewas29.17%(p<0.05);lntermsofphysicalstrength,theimprovementinthetreatmentgroupandtheimprovementinthecontrolgrouparemarked(p<0.05);Intermsoftoxicityreaction,twogroupsarenotfound.Conclusion:TheWeiAi-1-PrescriptionjointCapecitabinecanincreasethea

7、dvaneedgastriccancers'qualityoflife,ImprovetheTCMpoints,Reducethehand-footsyndrome;FurtherillustratesthatChinesemedicinecombinedwithchemotherapycansignificantlyimprovethequalityoflifeofpatientsandimproveefficacy.【关键词】老年晚期胃癌健脾养胃，解毒祛瘀法卡培他滨临床研究【英文关键词】advaneedgastriccancerwitholdagesJianPiYangWei,Ji

8、eDuQuYUCapecitabineClinicalinvestigation【目录】胃癌I号方联合卡培他滨方案治疗老年晚期胃癌临床观察目录6-8摘要8-9ABSTRACT!前言10-12第一部分理论研究12-241.中医学对本病的认识12-141.1中医文献对胃癌的论述121.2中医对胃癌病因的认识12-131.3胃癌病因病机分析131.4胃癌的治法研究13-142.胃癌的现代医学研究14-192.1晚期胃癌的定义142.2晚期胃癌的危险因素14-162.3晚期胃癌临床表现162.4晚期胃癌的诊断16-172.5晚期胃癌的病理表现及分期172.6晚期胃癌的化学治疗及研究进展17-193.中西医结合治疗晚期胃癌研究1