MF498 _Prostaglandin Receptor Antagonist - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEMF498Cat. No.: HY-10794CAS No.: 915191-42-3分式: CHNOS分量: 603.69作靶点: Prostaglandin Receptor作通路: GPCR/G Protein储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 31 mg/mL (51.35 mM)* means solubl

2、e, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 1.6565 mL 8.2824 mL 16.5648 mL5 mM 0.3313 mL 1.6565 mL 3.3130 mL10 mM 0.1656 mL 0.8282 mL 1.6565 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您现现配，当天使；

3、澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (4.14 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.5 mg/mL (4.14 mM); Clear solution3. 请依序添加每种溶剂： 10% DMSO 90% corn oil1/2 Master of Small

4、 Molecules 您边的抑制剂师www.MedChemESolubility: 2.5 mg/mL (4.14 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 MF498种新型的选择性前列腺素E4受体(EP4受体)拮抗剂，与EP4受体具有强亲和, Ki 为0.7 nM。户使本产品发表的科研献 J Virol. 2018 Sep 26;92(20). pii: e01018-18.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Clark P, et al. MF4

5、98 N-4-(5,9-Diethoxy-6-oxo-6,8-dihydro-7H-pyrrolo3,4-gquinolin-7-yl)-3-methylbenzylsulfonyl-2-(2-methoxyphenyl)acetamide, a selective E prostanoid receptor 4 antagonist, relieves joint inflammation and pain in rodent models of rMcePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021-58