医学微生物学英文教学课件：13 Zoonotic bacteria

1、Chapter 13 Zoonotic BacteriaDisease and infections which are naturally transmitted between vertebrate animal and man, such as anthrax, brucellosis, plague as known as zoonoses.These diseases are spread by direct contact with the animal or indirectly by such means as the ingestion of infected milk, c

2、ontact with infected food products, etc.BrucellaG-, coccobacilli; no spore, no flagella, micro-capsuleBlue-Light activation LOVbacteria multiplication CulturalGrow best in a medium enrich with animal serum and glucose, 37,5%10% CO2, slowly; small ,convex and smooth colony.Antigenic structure and cla

3、ssification A Ag (abortus antigen) M Ag (melitensis antigen) B.melitensis B.abortus B.suis B.canisPathogenicityBruce is essentially pathogens of goats, cattle, sheep, pig, etc. Human infections arise through contact with infected animals, including handling of infected carcasses, or through consumpt

4、ion of infected milk or milk products and dose not spread from man to man . Brucellosis symptoms: fever, sweat, headaches, back pain, and physical weakness. severe infection of the central nervous systems may occur. long-lasting or chronic symptoms： recurrent fevers，joint pain, and fatiguesluggard i

5、dlerImmunity humoral immunity cellular immunityG+ large rod, spore-forming no flagellaBacillus anthraciscultureAerobic and facultative anaerobicOrdinary media12-45,optimum 35 .Pathogenicity In animals, the portal of entry is the mouth and the gastrointestinal tract. In human, infection is usually ac

6、quired by the entry of spores through injured skin -cutaneous anthrax mucous membranes-gastrointestinal anthrax inhalation of spores into the lung -pulmonary anthrax Yersinia pestisG-, small coccobacillus capsule, non-sporing, non-motile, PathogenicityThe Yersinia pestis is essentially a parasite of rodents.Burrow animal such as gerbils and voles act as reservoirs of infection.May be transmitted by fleas to susceptible animal such as bandicoots, marmots and squirrels.The animals suffer from outbreaks of plague, and thei