BAY885 - ERK5 抑制剂 - 生命科学试剂 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEBAY885Cat. No.: HY-112082CAS No.: 2307249-33-6分式: CHFNO分量: 515.53作靶点: ERK作通路: MAPK/ERK Pathway; Stem Cell/Wnt储存式: -20C, stored under argon* In solvent : -80C, 6 months; -20C, 1 month (stored underargon)溶解性数据体外实验 DMSO : 16.67 mg/

2、mL (32.34 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 1.9398 mL 9.6988 mL 19.3975 mL5 mM 0.3880 mL 1.9398 mL 3.8795 mL10 mM 0.1940 mL 0.9699 mL 1.9398 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验 请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您现现配

3、，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 1.67 mg/mL (3.24 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 1.67 mg/mL (3.24 mM); Clear solutionBIOLOGICAL ACTIVITY1/2 Master of Small Molecule

4、s 您边的抑制剂师www.MedChemE物活性 BAY885是新颖的 ERK5 抑制剂。IC50 & Target ERK5 ERK5REFERENCES1. Nguyen D, et al. Discovery and Characterization of the Potent and Highly Selective (Piperidin-4-yl)pyrido3,2- dpyrimidine Based in VitroProbe BAY-885 for the Kinase ERK5. J Med Chem. 2019 Jan 24;62(2):928-940.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: