Zaltoprofen-CN100-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEZaltoprofenCat. No.: HY-B0619CAS No.: 74711-43-6Synonyms: CN100分式: CHOS分量: 298.36作靶点: COX作通路: Immunology/Inflammation储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 100 mg/mL (335.17 mM)* m

2、eans soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 3.3517 mL 16.7583 mL 33.5166 mL5 mM 0.6703 mL 3.3517 mL 6.7033 mL10 mM 0.3352 mL 1.6758 mL 3.3517 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液

3、，建议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (8.38 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.5 mg/mL (8.38 mM); Clear solution1/2 Master of Small Molecules 您边的抑制剂师www.M

4、edChemE3. 请依序添加每种溶剂： 10% DMSO 90% corn oilSolubility: 2.5 mg/mL (8.38 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Zaltoprofen(CN100)COX抑制剂，可作于关节炎。IC50 & Target COX-2 COX-1111 M (IC50) 149 M (IC50)REFERENCES1. Hirate, K., et al., Zaltoprofen, a non-steroidal anti-inflammatory drug, inhibits bradykinin-induced pain responses without blockingbradykinin receptors. Neurosci Res, 2006. 54(4): p. 288-94.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;