TAPI-1 - MMP 抑制剂 - 生命科学试剂 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemETAPI-1Cat. No.: HY-16657CAS No.: 171235-71-5分式: CHNO分量: 499.6作靶点: MMP作通路: Metabolic Enzyme/Protease储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 31 mg/mL (62.05 mM)* means soluble, but sa

2、turation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.0016 mL 10.0080 mL 20.0160 mL5 mM 0.4003 mL 2.0016 mL 4.0032 mL10 mM 0.2002 mL 1.0008 mL 2.0016 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。BIOLOGICAL ACTIVITY物活性 TAPI-1是特异的TACE（TNF-转换酶）抑制剂。户使本产品发表的科研献 Int J Endocrinol. 2017;201

3、7:9501792.1/2 Master of Small Molecules 您边的抑制剂师www.MedChemESee more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Zhang Y, et al. The human Cathelicidin LL-37 induces MUC5AC mucin production by airway epithelial cells via TACE-TGF-EGFRpathway. Exp Lung Res. 2014 Jun 5.2. Wheeler DL, e

4、t al. Protein kinase Cepsilon is linked to 12-O-tetradecanoylphorbol-13-acetate-induced tumor necrosis factor-alphaectodomain shedding and the development of metastatic squamous cell carcinoma in protein kinase Cepsilon transgenic mice. Cancer Res.2003 Oct 1;63(19):6547-55.3. Zhao XQ, et al. CRP enhances soluble LOX-1 release from macrophages by activating TNF- converting enzyme. J Lipid Res. 2011May;52(5):923-33.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;/p>