Pimelic-Diphenylamide-106-analog-RGFA-8-analog-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEPimelic Diphenylamide 106 analogCat. No.: HY-19430Synonyms: RGFA-8 analog; TC-H 106 analog分式: CHNO分量: 353.46作靶点: Others作通路: Others储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 30 mg/mL (8

2、4.88 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.8292 mL 14.1459 mL 28.2917 mL5 mM 0.5658 mL 2.8292 mL 5.6583 mL10 mM 0.2829 mL 1.4146 mL 2.8292 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。BIOLOGICAL ACTIVITY物活性 Pimelic Diphenylamide 106 类似物Pimel

3、ic Diphenylamide 106的类似物，活性未知。户使本产品发表的科研献 Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):2961-2966.1/2 Master of Small Molecules 您边的抑制剂师www.MedChemE J Mol Med (Berl). 2019 Jun 14.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Chou CJ, et al. Pimelic diphenylamide 106 is a slow,

4、tight-binding inhibitor of class I histone deacetylases. J Biol Chem. 2008 Dec19;283(51):35402-35409.2. Xu C, et al. Chemical probes identify a role for histone deacetylase 3 in Friedreichs ataxia gene silencing. Chem Biol. 2009 Sep25;16(9):980-989.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: 02