1-Linoleoyl-Glycerol-1-Linoleoyl-rac-glycerol-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemE1-Linoleoyl GlycerolCat. No.: HY-111346CAS No.: 2277-28-3Synonyms: 1-Linoleoyl-rac-glycerol; 1-Monolinolein分式: CHO分量: 354.52作靶点: Phospholipase作通路: Metabolic Enzyme/Protease储存式: Pure form -20C 3 years4C 2 yearsIn solvent -80C 6 m

2、onths-20C 1 month溶解性数据体外实验 DMSO : 100 mg/mL (282.07 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.8207 mL 14.1036 mL 28.2072 mL5 mM 0.5641 mL 2.8207 mL 5.6414 mL10 mM 0.2821 mL 1.4104 mL 2.8207 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验请根据您的实

3、验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (7.05 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.5 mg/mL (7.05 mM)

4、; Clear solution1/2 Master of Small Molecules 您边的抑制剂师www.MedChemE3. 请依序添加每种溶剂： 10% DMSO 90% corn oilSolubility: 2.5 mg/mL (7.05 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 1-Linoleoyl Glycerol从 S. chinensis 根中分离的种脂 酸油。IC50 & Target The (R)-1-Linoleoyl Glycerol and (S)-1-Linoleoyl Glycerol exhibit Lipo

5、protein-associated phospholipase A2(Lp-PLA2) inhibitory activities with IC50 values of 45.0 and 52.0 M, respectively 1.REFERENCES1. Lee WS, et al. Lp-PLA2 inhibitory activities of fatty acid glycerols isolated from Saururus chinensis roots. Bioorg Med Chem Lett. 2005Aug 1;15(15):3573-5.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021-