感染与心血管疾病课件

感染与心血管疾病

感染与心血管疾病

一、文献来源二、内容简介三、分析与讨论四、结论与启示一、文献来源一、文献来源1.Roleofacuteinfectionintriggeringacutecoronarysyndromes.LancetInfectDis2010;10:83–922.InfluenzaandCardiovascularDisease：IsThereaCausalRelationship?TexHeartInstJ.

2004;

31(1):4–13.3.ImmunosuppressiveTreatmentforInflammatoryCardiomyopathy.IntHeartJ2005;46:113-1224.Guidelinesontheprevention,diagnosis,andtreatmentofinfectiveendocarditis(newversion2009).EuropeanHeartJournal(2009)30,2369–2413.5.Efficacyofdaptomycininthetreatmentofenterococcalendocarditis:a5yearcomparisonwithconventionaltherapy.

JAntimicrobChemother.

2014Feb13,PMID:

24532682一、文献来源1.Roleofacuteinfecti1、感染（infection）系指由细菌、病毒、真菌、衣原体、支原体、立克次体、螺旋体、原虫、蠕虫等病原体所致的疾病。各类病原体可引起多种类型的感染致心血管疾病，使患者健康严重受损和社会负荷沉重不堪。2、感染导致心血管疾病以感染性心包炎、感染性心肌炎和感染性心内膜炎较常见，而感染性心瓣膜病多由感染性心内膜炎引起，感染性血管炎较为少见。3、诊治：在尽快留取实验室检查标本（如疑诊感染性心内膜炎患者至少抽3次静脉血进行血培养，采血间隔30min～1h）后，应根据循证医学和相关指南尽早、足量、经验性选用抗感染药物。二、内容简介1、感染（infection）系指由细菌、病毒、真菌、衣原体三、分析与讨论Roleofacuteinfectionintriggeringacutecoronarysyndromes.

LancetInfectDis2010;10:83–92三、分析与讨论RoleofacuteinfectionASeveralmechanismstriggerthedisruptionofanadvancedcoronarylesion.Thedisruptedsurfaceexposesunderlyingthrombogenicmaterial.Plaquedisruptionaloneisnotsufficientforthedevelopmentofanacutecoronarysyndrome.

BThrombogenicconditions(localandsystemic)determinethrombusformation.CTheocclusivenatureofthethrombus(totalvspartial),thedegreeofstenosis,thepresenceofvasoconstriction,thecoronaryperfusionpressure,andthemyocardialmetabolicbalance(demandvssupply)determinetheevolutionofanacutecoronarysyndrome.ASeveralmechanismstrigger2.InfluenzaandCardiovascularDisease：IsThereaCausalRelationship?TexHeartInstJ.

2004;

31(1):4–13.

2.InfluenzaandCardiovasculaTABLEII.EffectsofInfluenzaontheCoagulationSystemTABLEII.EffectsofInfluenza3.ImmunosuppressiveTreatmentforInflammatoryCardiomyopathy.IntHeartJ2005;46:113-1223.ImmunosuppressiveTreatment感染与心血管疾病课件感染与心血管疾病课件4.Guidelinesontheprevention,diagnosis,andtreatmentofinfectiveendocarditis(newversion2009).EuropeanHeartJournal(2009)30,2369–2413.4.Guidelinesontheprevention感染性心内膜炎的临床表现感染性心内膜炎的临床表现感染性心内膜炎的诊断标准感染性心内膜炎的诊断标准感染与心血管疾病课件5.Efficacyofdaptomycininthetreatmentofenterococcalendocarditis:a5yearcomparisonwithconventionaltherapy.

JAntimicrobChemother.

2014，13：PMID:

24532682Enterococcusspp.accountfor10%ofinfectiveendocarditis(IE)AlthoughdaptomycinisabactericidaldrugwithinvitroactivityagainstEnterococcus,thereislittleexperienceofitsuseinIE.Thiswasaretrospectivedescriptivestudycomparingtheefficacyofdaptomycinversusampicillin/ceftriaxoneversusconventionalantibioticregimens(ampicillinorvancomycin+gentamicin)inEIE5.EfficacyofdaptomycinintTable1.Baselinecharacteristicsofthe32patientswithenterococcalinfectiveendocarditisdiagnosedduringthestudyperiodTable1.Baselinecharacterist感染与心血管疾病课件1、感染引起心血管疾病的确诊比较困难，并且往往较晚，起始经验治疗对患者预后有着重要意义。2、病毒性心肌炎以对症支持治疗为主。虽然免疫参与了病程进展，但是抑制免疫的药物并不能改善患者的预后。3、根据ESC及BSAC指南，重症感染性心内膜炎起始经验治疗可启用万古霉素联合庆大霉素等。4、达托霉素单独治疗EIE，疗效并不优于上述传统治疗方案。四、结论与启示1、感染引起心血管疾病的确诊比较困难，并且往往较晚，起始经验谢谢DepartmentofMacromolecularScience--FudanUniversity谢谢DepartmentofMacromolecular后面内容直接删除就行资料可以编辑修改使用资料可以编辑修改使用后面内容直接删除就行主要经营：网络软件设计、图文设计制作、发布广告等公司秉着以优质的服务对待每一位客户，做到让客户满意！主要经营：网络软件设计、图文设计制作、发布广告等致力于数据挖掘，合同简历、论文写作、PPT设计、计划书、策划案、学习课件、各类模板等方方面面，打造全网一站式需求致力于数据挖掘，合同简历、论文写作、PPT设计、计划书、策划感谢您的观看和下载Theusercandemonstrateonaprojectororcomputer,orprintthepresentationandmakeitintoafilmtobeusedinawiderfield感谢您的观看和下载Theusercandemonstr感染与心血管疾病

感染与心血管疾病

一、文献来源二、内容简介三、分析与讨论四、结论与启示一、文献来源一、文献来源1.Roleofacuteinfectionintriggeringacutecoronarysyndromes.LancetInfectDis2010;10:83–922.InfluenzaandCardiovascularDisease：IsThereaCausalRelationship?TexHeartInstJ.

2004;

31(1):4–13.3.ImmunosuppressiveTreatmentforInflammatoryCardiomyopathy.IntHeartJ2005;46:113-1224.Guidelinesontheprevention,diagnosis,andtreatmentofinfectiveendocarditis(newversion2009).EuropeanHeartJournal(2009)30,2369–2413.5.Efficacyofdaptomycininthetreatmentofenterococcalendocarditis:a5yearcomparisonwithconventionaltherapy.

JAntimicrobChemother.

2014Feb13,PMID:

24532682一、文献来源1.Roleofacuteinfecti1、感染（infection）系指由细菌、病毒、真菌、衣原体、支原体、立克次体、螺旋体、原虫、蠕虫等病原体所致的疾病。各类病原体可引起多种类型的感染致心血管疾病，使患者健康严重受损和社会负荷沉重不堪。2、感染导致心血管疾病以感染性心包炎、感染性心肌炎和感染性心内膜炎较常见，而感染性心瓣膜病多由感染性心内膜炎引起，感染性血管炎较为少见。3、诊治：在尽快留取实验室检查标本（如疑诊感染性心内膜炎患者至少抽3次静脉血进行血培养，采血间隔30min～1h）后，应根据循证医学和相关指南尽早、足量、经验性选用抗感染药物。二、内容简介1、感染（infection）系指由细菌、病毒、真菌、衣原体三、分析与讨论Roleofacuteinfectionintriggeringacutecoronarysyndromes.

LancetInfectDis2010;10:83–92三、分析与讨论RoleofacuteinfectionASeveralmechanismstriggerthedisruptionofanadvancedcoronarylesion.Thedisruptedsurfaceexposesunderlyingthrombogenicmaterial.Plaquedisruptionaloneisnotsufficientforthedevelopmentofanacutecoronarysyndrome.

BThrombogenicconditions(localandsystemic)determinethrombusformation.CTheocclusivenatureofthethrombus(totalvspartial),thedegreeofstenosis,thepresenceofvasoconstriction,thecoronaryperfusionpressure,andthemyocardialmetabolicbalance(demandvssupply)determinetheevolutionofanacutecoronarysyndrome.ASeveralmechanismstrigger2.InfluenzaandCardiovascularDisease：IsThereaCausalRelationship?TexHeartInstJ.

2004;

31(1):4–13.

2.InfluenzaandCardiovasculaTABLEII.EffectsofInfluenzaontheCoagulationSystemTABLEII.EffectsofInfluenza3.ImmunosuppressiveTreatmentforInflammatoryCardiomyopathy.IntHeartJ2005;46:113-1223.ImmunosuppressiveTreatment感染与心血管疾病课件感染与心血管疾病课件4.Guidelinesontheprevention,diagnosis,andtreatmentofinfectiveendocarditis(newversion2009).EuropeanHeartJournal(2009)30,2369–2413.4.Guidelinesontheprevention感染性心内膜炎的临床表现感染性心内膜炎的临床表现感染性心内膜炎的诊断标准感染性心内膜炎的诊断标准感染与心血管疾病课件5.Efficacyofdaptomycininthetreatmentofenterococcalendocarditis:a5yearcomparisonwithconventionaltherapy.

JAntimicrobChemother.

2014，13：PMID:

24532682Enterococcusspp.accountfor10%ofinfectiveendocarditis(IE)AlthoughdaptomycinisabactericidaldrugwithinvitroactivityagainstEnterococcus,thereislittleexperienceofitsuseinIE.Thiswasaretrospectivedescriptivestudycomparingtheefficacyofdaptomycinversusampicillin/ceftriaxoneversusconventionalantibioticregimens(ampicillinorvancomycin+gentamicin)inEIE5.EfficacyofdaptomycinintTable1.Baselinecharacteristicsofthe32patientswithenterococcalinfectiveendocarditisdiagno