变态性皮肤病治疗课件

变态反应性皮肤病及治疗Evaluauononr.chAsposeslidesforNET4odientPEvaluationonly.CreatedwithAsposeSlidesforNET4.0dientProfilo71Copyright2019-2019AsposePtyL变凤应性皮肤病接蝕性皮炎ContactDermatitisCD湿疹Eczema药疹DrugeruptionEvaluauononr.chAsposeslidesforNET4odientPEvaluationonly.CreatedwithAsposeSlidesforNET4.0dientProfilo71Copyright2019-2019AsposePtyL接触性皮炎ContactdermatitisEvaluauononr.chAsposeslidesforNET4odientPEvaluationonly.CreatedwithAsposeSlidesforNET4.0dientProfilo71Copyright2019-2019AsposePtyL概述■定义:皮肤或黏膜接触致敏物后在接触部位发生的炎症反应。分类:原发刺激性接触性皮炎irritantdermatitis)变态反应性接触性皮炎(allergiccontactdermatitisEvaluauononr.chAsposeslidesforNET4odientPEvaluationonly.CreatedwithAsposeSlidesforNET4.0dientProfilo71Copyright2019-2019AsposePtyL病因与发病机理(Pathogenesisandetiology)病因:动物性:隐翅虫、松毛虫、斑蟊虫植物性:荨麻、补骨脂、银杏等化学性:染料、金属、化妆品、塑料发病机理:迟发型变态反应(Ⅳ型)Delayed-typehypersensitivityEvaluauononr.chAsposeslidesforNET4odientPEvaluationonly.CreatedwithAsposeSlidesforNET4.0dientProfilo71Copyright2019-2019AsposePtyL病因与发病机狸(Pathogenesisandetiology致敏物(半抗原)抗原提呈细胞→完全抗原」+|(APC:皮肤角质蛋白(载体蛋白T细胞活化、增殖致敏T细胞再次接触致敏物效应T细胞炎症因子Evaluauononr.chAsposeslidesforNET4odientPEvaluationonly.CreatedwithAsposeSlidesforNET4.0dientProfilo71Copyright2019-2019AsposePtyL临床表现(manifestation)■接触致敏物后发病,有一定的潜伏期。起病一般较急,病程较短;皮损好发于接触部位,主要是暴露部位;皮疹单一,一般为急性皮疹,境界清;■自觉瘙痒、烧灼感,可有疼痛感;■有自限性。Evaluauononr.chAsposeslidesforNET4odientPEvaluationonly.CreatedwithAsposeSlidesforNET4.0dientProfilo71Copyright2019-2019AsposePtyL硝酸刺激强碱刺激Evaluadononly.chAsposeslidesforNET4odientPEvaluationonly.CreatedwithAsposeSlidesforNET4.0dientProfilo71Copyright2019-2019AsposePtyL敌敌畏刺激化学物品刺激Evaluationonly.chAsposeslidesforNET4odientPEvaluationonly.CreatedwithAsposeSlidesforNET4.0dientProfilo71Copyright2019-2019AsposePtyL隐翅虫皮炎Evaluadononly.chAsposeslidesforNET4odient