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-26.

Journal

ofClinical

Medicine

inPractice

43

210022)

60

2

33

2

(P<0.05)

R735.2

R22

A

1672-2333(2222)22-023-04

D0I

10.7619/jcmp.

222222007

Clinical

effect

of

modified

Shenling

Baizhu

Powder

combined

with

apatinib

in

treeting

advanced

gastria

cancer

LIYu,

LINGBofan,XUE0£

DAIHong

(Departmentof'Oncology,JiangsuProvincialHospitalof'TraditionalChinese

Medicine,Naging,Jiangsu,210029)

Abstraci

:Objechvv

ToobservethdclinicaiefficacyofmoUifiedShedlingBaizhrPowdercom-

biaedwithaaatinininthetredtmeriofaivaaced

gasthccaacer.

Methods

Atotaiof66patieris

were

raniomiy

divinedintotoognupt,

with35casdtineactgnup.Thetreatmedignupwattreatedwith

moUifiedSdedlinaBaizhrPowOdncombined

withaaatinin,whilethdceutrotgnop

watonlytreated

withaaatinin.Thetreatmedieffectanithdiacinedco

ofddant

reactioot

werecomparedbetheed

thd

twogroopt.

Resultt

Thediseasecootroorateandeffectiverateoftraaitiooai

Chinesemedicine

syn­

dromeofthetreatwedt

groopweresivnificanWyhighea,

theiacinedco

ofaaversereactiooatovagrat-

ooewassivnificantinloweathaathatofthe

coo

WoIgroop(P<2.23).Conclusion

Theclinicai

effectofmooifiedShedlineBaizhpPowdeacombiaedwithaaatinininthetreatweat

of

gastria

caacenisbetteathaathatofaaatininaloae,antcombiaedtreatweat

caaredpcotheaCversereactioae

ofaaatinin

asweliasimprovatheqpdlityoflife.

Key

woait

:gastWocaaceainapaaad

stage;ShealinaBaizhpPowdea

aaatinin;atverse

re-

actioay

qpalityoflife

2

5

3%

~22%

[

o

,

2222-11

-15

(BK221510/6

RC221924

Y2219CX23

E-mail

***************

24

JournalofClinicalMedicineinPractice

24

1

1.1

2216

6

—2219

12

66

30

16

6

30-75

62

22

4

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5

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9

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63

21

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8

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P

>0.05

),

AJCC

7

TNM

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30d

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m15/

5

/

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5

/

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1.3

RECIST[

CR

PR

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(PD

ORR

=(CR+PR

X150%

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=(CR+PR+

SD

X100%

WHO

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3

12

3

>2/3

>1/3

~2/3

1/3

=

+

X100%

1.0

SPSS19.0

t

P<0.05

2

2.1

2

5

10

8

8

9

13

DCR

77.7%

3

50.0%

,

ORR

43.3%

26.0%

,

(P<0.05)

2.0

2

2

1-

2

>1

24

JournalofClinicalMedicineinPractice

25

(P

<

0.05

1

1

2

[”

)]

>1

1

2

3

4

15

5

2

0

7(23.3)

15

2

0

0

2(6.0)*

8

5

5

0

62000)

5

5

0

0

1303)*

3

6

2

0

8(26.7)

4

2

0

0

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5

6

5

0

7(23.3)

3

5

0

0

1(30)*

4

4

5

0

51607)

3

5

0

0

1(3.3)

*P<0.05

40

2

4

15

11

63.3%

5

5

4

93.3%

(P<0.05)

3

4

VEGFR-2

MDR

li

1~2

CD4

FOLFOX4

0.05

[15]

Meta

NK

T

B

[1

FERLAY

jjSOERJOMATARAM

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etal.Caee-

enieciCeeceana

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[J].

lethCaecen,

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EDGESB

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CC.

TheAmericae

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the7theeitiouoftheAJCCcancerstagingmac-

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JooreclofCliniceiMedicineinPractice

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39.

[14]

,

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.

FOLFOX4

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84-8.

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Meta

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67-68

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.

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151-156.

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BGCB23

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932-937.

(

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14(2)

:77-79.

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FIATKAUR,

LEWIAZKIV,KUHNTT,

eal.

AdPeauBpe-

cPicerterai

nututiou

FoeMulaimproves

nutetionai

statusanC

functiouai

peUormaace

inpatiedts

withheal

anCeeck.anCe-

sopha/eai

caacec

uuaeraoine

chemoranmtherapy

:results

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ranComized,conUolled,

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AranComizedthalcom-

parine

postoperahve

adjuvact

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anC

3-Buoropraci-

versus

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ceemotUerany

Uelocalized

anvacced

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Guinelices

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