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第1题Whichofthefollowingisthemostreliablemethodfortumordiagnosis?AX-rayexaminationBPalpationCCTscanDPathologicaldiagnosis第2题Whatisthebeginningofpathomorphology?AEstablishmentoffluidpathologyB
EstablishmentofultrapathologyCEstablishmentoforganpathologyDEstablishmentofimmunopathology第3题Whichofthefollowingarethecontentsofpathology?AEtiologyBPathogenesisCPathologicchangesDProgressionandoutcomes正确答案:ABCD第1题A69-year-oldmanhasahistoryofhypertension.Theheartatautopsyisshownintheimages.Whichofthefollowingtermsbestdescribesthesemorphologicchangesoftheheartofthispatient?AMetaplasiaBHyperplasiaCHypertrophyDAtrophy第2题A45-year-oldwomanhasahistoryofdiffusenontoxicgoiter.Thefollowingpicturesshowedgrossandhistologicappearanceofherthyroid.Whichofthefollowingtermbestdescribesthesemorphologicchangesofherthyroid?AAtrophyBHyperplasiaCHypertrophyDMetaplasia第3题A40-year-oldmanloseshisrightkidneyduetomalignanttumor.ACTscan2yearslatershowsmarkedenlargementofhisleftkidney.Therenalenlargementisanexampleofwhichofthefollowingadaptativechanges?AAtrophyBDysplasiaCHyperplasiaDHypertrophy第4题A30-year-oldmansustainsaleftfemoralfracture.Thenhisleftleghasbeenimmobilizedforseveralweeks.Whichofthefollowingadaptationmostlikelyoccursinhisleftcalfmuscles?AAplasiaBhyperplasiaChypertrophyDAtrophy第5题A55-year-oldmanhasahistoryofgastroesophagealrefluxdisease.Histologicexaminationoftheabnormaltissueinhisesophagusshowsintestine-likeepitheliumsimilartoincompletelyintestinalizedgastricmucosa.Whichofthefollowingtermsbestdescribesthismorphologicchangeintheesophagusofthispatient?AMetaplasiaBHyperplasiaCHypertrophyDAtrophy第6题A38-year-oldmanexperienceschronic
atrophic
gastritis.Heundergoesuppergastrointestinalendoscopy,andabiopsyspecimenofhisstomachisobtained.Thehistologicphotographshowstheappearanceofthespecimen.Whichofthefollowingisthemostlikelydiagnosis?ASquamousmetaplasiaBMucosalhypertrophyCIntestinal
metaplasiaDAtrophyoflaminapropria第7题Thefollowingpicturesshowgrossandhistologicappearanceofscartissue.Thischangeismostlikelytoresultfromwhichofthefollowingalterations?AFattychangeBCellularedemaCHyalinechangeDAmyloidchange第8题Afterexperiencingmalaisefor6weeks,a42-year-oldmanseeshisphysician.SerologictestresultsarepositiveforHBsAg.Liverbiopsyshowsthelivercellswerediffuselyswollen,ballooning(shownintheimage).Whichofthefollowingisthemostlikelydiagnosis?ACelluaredemaBFattychangeCHyalineChangeDAmyloidChange第9题Inwhichofthefollowingconditionsismucoiddegenerationseen?ACardiovascularwallinacuterheumatismBMesenchymaltumorsCHypothyroidismDArteriolesinmalignanthypertension正确答案:ABC第10题Thefollowingpictureshowshistologicappearanceofhearttissuebiopsyfromaveryobeseman.Whichofthefollowingisthemostlikelydiagnosis?AFattychangeBFattyinfiltrationCEdemaDLipofuscinaccumulation第11题A70-year-oldmanhasahistoryofatherosclerosis.Histologicexaminationofhisheartisshownintheimage.Granularbluedepositscanbefoundinthewallofcoronaryartery.Whichofthefollowingisthemostlikelydiagnosisforthedeposits?AMucoidchangeBDystrophiccalcificationCMetastaticcalcificationDHyalinechange第12题A
60-year-oldmanhasalonghistoryofalcoholabuse.
Atautopsy,theliverenlargesandbecomesyellow,soft,andgreasy.SudanⅢstainofthelivertissueshowsorangeincolour.Histologicappearanceofhisliveratautopsyisshownintheimage.Whichofthefollowingisthemostlikelydiagnosisoftheliver?AEdemaBFattychangeCAmyloidosisDHyalinedegeneration第13题A55-year-oldmanexperiencedchestpainbeforehisdeath.Ahistologicsectionofleftventricularmyocardiumtakenatautopsyshowedinthefollowingimage.Whichofthefollowingisthemostlikelydiagnosis?ACoagulativenecrosisBHyperplasiaCHypertrophyDLiquefactivenecrosis第14题A33-year-oldwomanhashaddecreasedurineoutputforthepastweek.Laboratorystudiesshowserumcreatininelevelof4.3mg/dLandureanitrogenlevelof40mg/dL.Arenalbiopsyisperformedandthespecimenisexaminedusingelectronmicroscopy.Whichofthefollowingmorphologicchangesmostlikelysuggestsadiagnosisofacutetubularnecrosis?AMitochondrialswellingBPlasmamembraneblebsCMitosisDNuclearfragmentation第15题Achestradiographof40-year-oldmanshowsalesionintherightlung.Thelesionisexcised.Thefollowingimagesshowsthegrossandhistologicappearanceofthelesion.Cultureoftissuefromthelesiongrowsmycobacteriumtuberculosis.Whichofthefollowingisthemostlikelydiagnosis?AApoptosisBCaseousnecrosisCFatnecrosisDFattychange第16题A40-year-oldmanhasviralhepatitis.Ahistologicsectionofhislivershowsmorphologyofasinglecellinthefollowingimage.Whichofthefollowingisthemostlikelydiagnosis?ACelluaredemaBApoptosisCHyalineChangeDPathologicPigmentation第17题Aconstructionworkerhasbeenaccidentallystabbedwitharustynailofhisrightlegafewdaysearlier.Inrecent2days,thebodytemperaturewasover39°c,therightcalfishighlyswollen.Thereiscrepituswhentouchingtherightcalf.Thepatientissoonunconscious.Whichofthefollowingisthemostlikelydiagnosisofhisrightleg?AWetgangreneBLiquefactivenecrosisCDrygangreneDGasgangrene第18题Whichofthefollowingcanbetheconsequencesofnecrosis?ALysisandabsorptionBIsolationandeliminationCOrganizationDEncapsulationandCalcification正确答案:ABCDTissuerepair_test第1题A12-year-oldboysufferstraumaticinjurytotheskinonhisrightleg.Twodayslater,thewoundbecomepinkandgranularappearance.Thefollowingimageshowsthehistologicappearanceofthislesion.Whichofthefollowingisthemostlikelypathologicdiagnosis?AKeloidBScartissueCGranulationtissueDFibrinoidnecrosis第2题DuringtherepairprocessofthepatientdescribedinQuestion1,whichofthefollowingcelltypeswouldshowtheweakestregenerativecapacity?AVascularendothelialcellsBEpidermalcellsCSkeletalmusclecellsDFibroblasts第3题A62-year-oldmanhadchestpainpersistingfor4hours.Aradiographicimagingprocedureshowedaninfarctionoftheanteriorleftventricularwall.Laboratoryfindingsindicatedmyocardialinfarction.Whichofthefollowingpathologicfindingswouldmostlikelybeseenintheleftventricularlesionthreemonthslater?AFibrousscarBCompleteregenerationCAcuteinflammationDGranulationtissue第4题A20-year-oldmanlaceratedhisrightarmandrequiredsutures.Thesutureswereremoved1weeklater.Thesitebecamedisfiguredoverthenexttwomonths.Thefollowingpicturesshowthemacroscopicandhistologicappearanceofthelesion.Whichofthefollowingtermsbestdescribestheprocessthatoccurredinthisman?ACompleteregenerationBMetaplasiaCKeloidformationDNecrosis第5题A29-year-oldwomanunderwentCaesareansectionfourmonthsago.Aneatandlinearscarformedinasuturedwound.Whichofthefollowingtermsbestdescribestherepairprocess?AHealingbyfirstintentionBHealingbysecondintentionCCompleteregenerationDUnhealed第6题WhichofthefollowingnutritionalfactorsisrequiredforpropercollagenassemblyinthescartissueofthepatientdescribedinQuestion5?AVitaminEBVitaminCCVitaminBDVitaminA第7题A25-year-oldmansuffersaskinlacerationonhisrightkneebyaccident.Thewoundiscleanedbyhimself.Whichofthefollowingistheinitialeventinthewoundhealingprocess?AIngrowthofgranulationtissueBFormationofabloodclotCMacrophage-mediatedphagocytosisofcellulardebrisDDepositionofcollagen第8题Whichofthefollowingcelltypesfunctionsascontraction-mediatorinfacilitatingthehealingprocessofthepatientdescribedinQuestion7?ANeutrophilsBMacrophagesCFibroblastsDMyofibroblasts第9题WhichofthefollowingisthemostimportantfactorthatdetermineswhetherthewoundinthepatientdescribedinQuestion7willhealbyfirstorsecondintention?ATissuelossandappositionofwoundedgesBNutritionalstatusCBloodsupplyDMetabolicstatusLocalCirculatoryDisturbances_test第1题A
patient
suffered
from
acuteleftsidedheart
failure.
The
histological
appearance
of
the
patient’s
lung
tissue
is
shown
in
the
following
pictures.
Whichofthefollowingisthemostlikelydiagnosis?ACongestionandedemaofthelungBHemorrhageofthelungCNecrosisofthelungDEmbolismofthelung第2题Apatienthaschroniccongestionoflungs.Thefollowingpictureshowsthehistologicalappearanceofhislung.Theblackarrowspointtosomegiant
and
deep
stainingcells.The
pathological
pigment
in
the
cytoplasm
is:ABilirubinBHemosiderinCLipofuscinDMelanin第3题Duringhospitalization,a45-year-oldwomandevelopsthrombophlebitisinafemoralvein.Thefollowingimageshowsthemorphologyofthethrombusafter2weeks.Whichofthefollowingtermsbestdescribestheprocessseeninherfemoralveinafterrecoveryfromherthrombophlebitis:AAcuteinflammationBHaemorrhageCEmbolizationDOrganization第4题Redthrombusismostcommonin:AtheheadofthrombusBthemiddleofthrombusCtheendpartofthrombusDheartvalvesheartvalves第5题A55-year-oldwomanhasbeentreatedinthehospitalforpancreatitisforthepastthreeweeksandisfoundtohaveaswollenrightleg.Itistendertopalpationbutisnotwarm.Thisconditionismostlikelytobetheresultofwhichofthefollowingvascularcomplications?ACongestiveheartfailureBSepticembolizationCVenousthrombosisDArterialhyperemia第6题Inapatientwithmyocardialinfarction,thereisalesionintheventricularwall.Thefollowingimagesshowgrossandhistologicalappearanceofthelesion.Whichofthefollowingisthemostlikelydiagnosis?()ARedthrombusBWhitethrombusCMixedthrombusDHyalinethrombus第7题Apatientsuffersfromdisseminatedintravascularcoagulation(DIC).Thefollowingimageshowsthelesionmicrocirculation.Themajorcomponentofthislesion(blackarrow)is()APlateletBRedbloodcellCLeukocyteDFibrin第8题A62-year-oldmanhasexperiencedsubsternalchestpainuponexertionwithincreasingfrequencyoverthepast6months.Anelectrocardiogramshowsfeaturesconsistentwithischemicheartdisease.Hehasatotalserumcholesterolof262mg/dL.Byangiography,thereis75%narrowingoftheleftanteriordescendingartery.Whichofthefollowingvascularcomplicationsismostlikelytooccurinthispatient?AsystemicarteryembolusfromthrombosisinaperipheralveinBPulmonaryembolismfromthrombosisinaperipheralveinCPulmonaryembolismfromaleftventricularmuralthrombusDAsystemicarteryembolusfromaleftventricularmuralthrombus第9题Mostcommontypeofembolismis___AgasembolismBthromboembolismCfatembolismDamnioticfluidembolism第10题Thepulmonaryembolusmostlycomesfrom:AdeepveinsoflowerlimbBleftatriumCarterialDleftventricle第11题Apatientwithchronicleftheartcongestionhaspulmonarythromboembolism.Thefollowingimagesshowalesioninhislung.Whichofthefollowingisthemostlikelydiagnosis?(
)ALiquefactivenecrosisoflungBWhiteinfarctsoflungCAbscessoflungDHemorrhagicinfarctsoflung第12题Themostcommonreasonofinfarctis___AOcclusionofamajorarteryBArterialspasmCVenousocclusionDThrombosis第13题Whichofthefollowingorgansareeasilytodevelopwhiteinfarction?AKidney,Brain,IntestineBKidney,Lung,HeartCSpleen,Kidney,HeartDLung,Heart,Intestine第14题Apatienthasahistoryofrightheartfailure.Thefollowingimagesshowthegrossandhistologicappearanceofhisliver.Whichofthefollowingdescriptionarecorrectfortheliver?AFattychangecanbefound.BHemorrhagecanbeseen.CGrosslythecutsurfaceoftheliverlookslikenutmeg.DWithmanyregenerativenodules.正确答案:ABC第15题Whichofthefollowingconditionsillustratetheconceptofactivehyperemia?AHyperemiaafterdecompressionBBlushingfromembarrassmentCHyperemiaofskeletalmuscleduringheavyexerciseDGastrointestinalhyperemiaaftermeals正确答案:ABCD第16题Whichofthefollowingarethecausesofcongestion?ALocalvenouscompressionBLocalorsystemicvenousobstructionCCardiacfailureDIncreaseofvasoactivesubstances正确答案:ABC第17题Whichofthefollowingareconsequencesofchroniccongestionoflung?AinterstitialfibrosisBedemaChemorrhageDNecrosis正确答案:ABCD第18题Whichofthefollowingaremainpredisposingfactorsforthrombosis?AEndothelialinjuryBChangesinbloodflowCIncreasedcoagulabilityofbloodDThrombopenia正确答案:ABCInflammation_test第1题Whatsituationdoesinflammatiooccur()AAnlylivingorganismBLlivingorganismwithavascularsystemCDeadorganismDSingle-celledorganism第2题Whichisthemostimportantpathologicfeatureofinflammation()ADegenerationBNecrosisCExudationDProliferation第3题WhichisthemostcommoncauseofinflammationAPhysicalagentsBMicrobiologicalagentsCChemicalagentsDImmunereactions第4题Theformationofexudateismainlydueto()AIncreasedintravascularhydrostaticpressureBDecreasedintravascularcolloidosmoticpressureCObstructionoflymphaticdrainageDIncreasedvascularpermeability第5题Whichstepofhemodynamicchangeiscausedbyincreasedvascularpermeability()AArteriolarvasodilationBArteriolarvasoconstrictionCIncreaseinbloodflowDBloodstasis第6题Whichisthemostcommonmechanismofincreasedvascularpermeability()AEndothelialcellcontractionBIncreasedtranscytosisCEndotheliuminjuryDLeakagefromthenewcapillaries第7题Whichofthefollowingitemswouldbeinfluencedbyadefectofintegrinexpressiononleukocytesintheprocessofleukocyteexudation()AMarginationBRollingCAdhesionDTransmigration第8题Whichofthefollowingchemicalsubstancesmaymakeleukocytesdirectionallymigratetowardstheinflamedareaalongaconcentrationgradient()ANitricoxideBROSCProstaglandinDC5a第9题WhichofthefollowingcelltypesisthefirstcelltotransmigratethroughthevesselwallintotheinflamedsiteAneutrophilBmacrophageCeosinophilDlymphocyte第10题A6-year-oldboyhasahistoryofrecurrentinfectionswithpyogenicbacteria.Geneticanalysisofperipheralbloodneutrophilsshowsadeficiencyinmyeloperoxidase.Anabnormalityinwhichofthefollowingprocessesisthemostlikelycauseofthisboy’srecurrentinfections()ALeukocyteadhesiontoendotheliumBLeukocytetransmigrationCRecognitionofmicrobesDKillingofingestedmicrobes第11题Opsonizationoccursinwhichstepoftheprocessofphagocytosis()ARecognitionandattachmentBEngulfmentCKillingoftheingestedmaterialDDegradationoftheingestedmaterial第12题Whichofthefollowingchemicalsubstancesismostlikelytoenhanceleukocyticphagocytosis()AHistamineandserotoninBComplementC3bandIgGCInterleukin-1andtumornecrosisfactorDIntegrinandselectin第13题Herpeszostervirusmaycauseskinlesionshowninthefollowingpicture.Whatisthemostlikelypathologicdiagnosisabouttheskinlesion(
)ASerousinflammationBFibrinousinflammationCSuppurativeinflammationDGranulomatousinflammation第14题Amandiedofuremia.Autopsywasperformed.Thegrossandmicroscopicappearancesofhisheartareshowninthepictures.Themostlikelydiagnosisis()APurulentpericarditisBserouspericarditisCConstrictivepericarditisDFibrinouspericarditis第15题Whattypeofinflammationdoespseudomembranousinflammationbelongto()ASerousinflammationBFibrinousinflammationCSuppurativeinflammationDGranulomatousinflammation第16题Suppurativeinflammationischaracterizedbyexudationofwhattypeofinflammatorycell()ALymphocyteBMacrophageCNeutrophilDEosinophil第17题Whichofthefollowingitemsbelongstoabscess()AAcutephlegmonousappendicitisBAcutepyogenicmeningitisCAcutebacillarydysenteryDCarbuncle第18题Whichofthefollowingitemsisconsistentwiththisdefinition:AnabnormaltractleadingfromafocusofdeepabscesstoacutaneousormucosalsurfaceAUlcerBFistulaCSinusDCavity第19题Whichofthefollowingdiseasesbelongstosuppurativeinflammation()ALobarpneumoniaBHairheartCAcutephlegmonousappendicitisDEpidemicencephalitisB第20题Thegrossappearanceofthecervicalmassisshowninthefollowingpicture.Microscopically,themasscontainshyperplasticepithelium,glands,andconnectivetissueaccompaniedbylargeamountoflymphocyteinfiltrate.Whatisthemostlikelypathologicdiagnosisofthemass(
)AInflammatorypolypBInflammatorypseudotumorCGranulomaDGranulationtissue第21题Whatisnodularcollectionofproliferatingmacrophagesandmacrophage-derivedcells()AInflammatorypolypBInflammatorypseudotumorCGranulomaDGranulationtissue第22题Surgicalsuturesmaystimulatetheformationofsomegiantcellswiththehistologicfeatureshowninthefollowingpicture.Whatisthegiantcellcalled(
)AEpithelioidcellBLanghansgiantcellCForeign-bodygiantcellDTumorgiantcell第23题WhataretheprinciplecellularcomponentsoftuberculousGranuloma()AEpithelioidcellsandforeign-bodygiantcellsBEpithelioidcellsandLanghansgiantcellsCMacrophagesandfibroblastsDMacrophagesandlymphocytes第24题WhichitemsarecorrectaboutchronicnonspecificinflammationATheprincipleinflammatorycellsaremacrophages,lymphocytes,andplasmacellsBTissueinjuryandtissuerepairproceedsimultaneouslyCChronicnonspecificinflammationoccurringinmucosamayforminflammatorypolypDMacrophage–Neutrophilinteractionsplayanimportantroleinthedevelopmentandmaintenanceofchronicinflammation正确答案:ABCNeoplasm_test1第1题A45-year-oldwomanpresentswithabdominalpainandvaginalbleeding.Ahysterectomyisperformedandshowsabenigntumoroftheuterusderivedfromsmoothmusclecell.Whatistheappropriatediagnosis?ALeiomyomaBAdenomaCTeratomaDHamartomaEFibroma第2题A50-year-oldmanpresentedwithaone-yearhistoryofprogressivedysphagia.Thefollowingimageshowsthemicroscopicappearanceofthetumorfoundinhisesophagus.Whatisthemostlikelydiagnosis?AAdenocarcinomaBMelanomaCLeiomyosarcomaDSquamouscellcarcinomaESquamouspapilloma第3题A63-year-oldmanhasnoticedincreasingmalaise.Onphysicalexamination,thestoolguaiactestispositive.Acolonoscopyisperformed,a4-cmmassisfoundinthesigmoidcolon.Oneweeklater,themassissurgicallyremoved,andthegrossandmicroscopicappearanceofthemassisshowninthefollowingpictures.Whichofthefollowingisthemostlikelydiagnosis?ASquamouscellcarcinomaBAdenocarcinomaCHamartomaDAdenomaESquamouspapilloma第4题A20-year-oldwomanhasanovariantumorexcised.Thesurgicalspecimenis10cmindiameterandcystic.Onmacroscopicexamination,thecysticmassisfilledwithblackhairandsebaceousmaterial.Histologically,squamousepithelium,glandularepithelium,cartilage,andfibrousconnectivetissuearepresentandresemblenormaltissuecounterparts.Whatisthemostlikelydiagnosis?AAdenomaBAdenocarcinomaCTeratomaDHamartomaEFibroadenoma第5题A30-year-oldwomanhasapositivestoolguaiactestduringaroutinephysicalexamination.Acolonoscopyisperformed,anda1.2-cm,circumscribed,pedunculatedmassonashortstalkisfoundintheupperportionofthedescendingcolon.Thefollowingimageshowsthemicroscopicappearanceofthemass.Whichofthefollowingtermsbestdescribesthislesion?ASarcomaBAdenomaCSquamouscellcarcinomaDFibromaELeiomyoma第6题A34-year-oldwomanundergoaroutinehealthexamination.APapsmearwasobtained,andtheresultreportedwasabnormal.Sheiscurrentlyasymptomaticandhasahistoryofhumanpapillomavirus(HPV)infection.Cervicalbiopsyspecimensareobtainedandthefollowingfigureshowsthemicroscopicappearance.Whichofthefollowingtermsbestdescribesthislesion?ACarcinomainsituBAdenocarcinomaCSquamouscellcarcinomaDHamartomaECINI第7题A55-year-oldmanpresentswithalumpinthesofttissueofhisleftshoulder.Physicalexaminationrevealsa0.8-cmsubcutaneoustumor.Thefollowingfigureshowsthemicroscopicappearanceofthetumor.Whatisthemostlikelydiagnosis?APapillomaBAdenomaCLeiomyomaDLipomaEFibroma第8题A73-year-oldmanhashadaslowlyenlargingnoduleonhislefteyelidfor3years.Thelesionisexcised,butmultiplefrozensectionsaremadeduringthesurgerytominimizetheextentoftheresectionandpreservetheeyelid.Themicroscopicappearanceofthelesionisshowninthefollowingpicture.Whatisthemostlikelydiagnosis?ASquamouscellcarcinomaBAdenocarcinomaCFibrosarcomaDLiposarcomaEBasalcellcarcinoma正确答案:E第9题A26-year-oldwomanhasnotedarednoduleontheskinofherneck.Shereportsthatthenodulehasbeenpresentformanyyearsandhasnotchangedinsize.Itisexcised,andthemicroscopicappearanceisshowninthefollowingimage.Whichofthefollowingneoplasmsisthislesionmostlikelytobe?AHemangiomaBFibroadenomaCLeiomyomaDLipomaEMelanoma第10题A32-year-oldwomanhadnoticedalumpinherrightbreast.Onphysicalexamination,a2.2-cm,circumscribed,freelymovablemassinthelowerouterquadrantispalpable.Themassissurgicallyremoved,andthemicroscopicappearanceofthemassisshowninthefigureatlow(A)andhigh(B)magnifications.Whatisthemostlikelydiagnosis?ALipomaBPapillomaCFibromaDFibroadenomaEHemangioma第11题An89-year-oldmandiespeacefullyinhissleep.Atautopsy,arestofpancreatictissueisidentifiedinthewalloftheloweresophagus.Thisfindingrepresentsanexampleofwhichofthefollowingconditions?ATeratomaBHemangiomaCChoristomaDPapillomaEAdenoma第12题A26-year-oldwomanpresentswithmultiplepapulesonthebackofherrighthand.Histologicexaminationofalesionisshowninthefigureatlow(A)andhigh(B)magnifications.Whatisthemostlikelydiagnosis?APapillomaBHemangiomaCLipomaDFibromaEAdenoma第13题WhichofthefollowingvirusesismostlikelyresponsibleforthedevelopmentoftheskinlesionsinQuestion12?AEpstein-BarrvirusBHumanpapillomavirusCCytomegalovirusDHumanherpesvirustype8EHerpessimplexvirustype2第14题A49-year-oldwomanpresentswitha3-monthhistoryofabdominaldiscomfortanddarkstools.Physicalexaminationshowspallorbutnoevidenceofjaundice.Abariumswallowradiographrevealsa“leatherbottle”appearanceofthestomach.Thebiopsyisshowninthefigureatlow(A)andhigh(B)magnifications.Whichofthefollowingisthemostlikelydiagnosis?ABasalcellcarcinomaBChoristomaCLeiomyosarcomaDSquamouscellcarcinomaESignetringcellcarcinoma正确答案:E第15题A24-year-oldmanisadvisedtoseehisphysicianbecausegeneticscreeninghasdetectedadiseaseinotherfamilymembers.Onphysicalexamination,astoolsampleispositiveforoccultblood.Acolonoscopyisperformed,followedbyacolectomy.Thefollowingimageshowsthemacroscopicappearanceofthemucosalsurfaceofthecolectomyspecimen.Microscopicexaminationshowstheselesionsaretubularadenomas.Molecularanalysisofthispatient’snormalfibroblastismostlikelytoshowmutationinwhichofthefollowinggenes?AMLH1BRBCp53DAPCEBRCA1Neoplasia_test2第1题Whichofthefollowingfeaturesismostlikelydemonstratedbythemicroscopicappearanceofmalignanttumor?AAnaplasiaBAplasiaCHyperplasiaDDysplasiaEMetaplasia第2题Whichofthefollowingcharacteristicsismostlikelytobepredictedbythesub-clonesoftumorcells?AAngiogenesisBInvasivenessCDifferentiationDHeterogeneityEAneuploidy第3题A44-year-oldwomannotesa5cmdiameternon-tendermassintheupperouterquadrantofherleftbreast.Afineneedleaspirationofthismassisperformed,andcytologicallythecellsareconsistentwithinfiltratingductalcarcinoma.Another2cmnon-tendermassispalpableintheleftaxilla.Achestradiog
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