L-Cystine-dihydrochloride-Standard-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors•ScreeningLibraries•Proteinswww.MedChemEL-Cystinedihydrochloride(Standard)Cat.No.:HY-W009203RCASNo.:30925-07-6分⼦式:C₆H₁₄Cl₂N₂O₄S₂分⼦量:313.22作⽤靶点:EndogenousMetabolite;Apoptosis;Keap1-Nrf2;ReactiveOxygenSpecies(ROS);Ferroptosis;ReferenceStandards作⽤通路:MetabolicEnzyme/Protease;Apoptosis;NF-κB;Immunology/Inflammation;Others储存⽅式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY⽣物活性L-Cystine(dihydrochloride)(Standard)L-Cystine(dihydrochloride)(HY-W009203)的分析标准品。本产品⽤于研究及分析应⽤。L-CystinedihydrochlorideL-Cystine(HY-N0394)的盐酸盐形式。L-Cystinedihydrochloride升⾼Nrf2蛋⽩表达含量并激活Nrf2转录因⼦。L-Cystinedihydrochloride减少了REFERENCES[1].AbdullahM,etal.ExtracellularConcentrationofL-CystineDeterminestheSensitivitytoSystemxc-Inhibitors[J].BiomolTher(Seoul).2022Mar1;30(2):184-190.[2].KuriharaS,etal.Enhancementofantigen-specificimmunoglobulinGproductioninmicebyco-administrationofL-cystineandL-theanine[J].JVetMedSci.2007Dec;69(12):1263-70.[3].DominiqueBazin,etal.CystinuriaandcystinosisareusuallyrelatedtoL-cystine:isthisreallythecaseforcystinosis?Aphysicochemicalinvestigationatmicrometreandnanometrescale.ComptesRendus.Chimie,Volume25(2022)no.S1,pp.489-502.[4].GrethWE,etal.CellularaccumulationofL-cystineinratkidneycortexinvivo[J].JClinInvest.1973Feb;52(2):454-62.[5].OhtsuI,etal.UptakeofL-cystineviaanABCtransportercontributesdefenseofoxidativestressintheL-cystineexport-dependentmannerinEscherichiacoli.PLoSOne.2015Apr2;10(3):e0120619.[6].DaiW,etal.FreshMediumorL-CystineasanEffectiveNrf2InducerforCytoprotectioninCellCulture[J].Cells.2023Jan12;12(2):291.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-37