肾病总论(英语)张玖强.pptx

1、Urinary System Disease,Liu Fu-You MD.,1. Reviews of Anatomy and Physiology of Urinary System,(1) kidney L T11L2 R T12L3,10cm in length 5cm in width 4cm in thickness 134 148g in weight,(1) kidney,(2) Renal Cortex,renal cortex 8090% of glomerulus Glomerular capsule renal medulla renal tubule,(3) Glome

2、rulus,Glomerular Filtration Membrane endothelial cells basement epithelial cells,(4) Renal tubule,proximal convolute reabsorption distal convolute regulating of acid-base balance,Renal tubular diseases,(renal, tubular, acidosis),Type (dRTA),Type (pRTA),+,(5) Renal Interstitium,Interstitial cells Fib

3、rocyte Extracelluar matrix,Pathogenic microorganism immunoreaction,Acute interstitial nephritis Chronic interstitial nephritis,Interstitium,(6) Renal Pelvis, Ureter,Renal pelvis ureter,Pathogenic microorganism,pyelonephritis,(upper urinary tract),(7) Urinary Bladder,Urethra,Urinary bladder Urethra,(

4、Lower urinary tract),Pathogenic microorganism,cystourethritis,2. Symptoms of Glomerular Disease,Proteinuria hematuria edema hypertension,nephritis syndrome,(proteinuria3.5g/day) Proteinuria+,nephrotic syndrome,proteinuria150mg/24hr,Proteinuria analysis,glomerular tubular overflow secretory or 1.5g/2

5、4hr 1.5g/24hr immunoglobulin histic,2-micro globulin Infection toxicity,Bence Jones protein,myeloma,Selective (albumin),Non Selective (mixture),hematuria,Dysmorphic Rbc,Hemogeneous Rbc,Calculus,tumor, TB,infection,Glomerular disease,hypertension,renal parenchyma,Renal vesselArleriae renalis stenosis

6、,volume dependent renin dependent,Edema,Glomerular Filtrate Rate (GFR) ,Plasma colloid osmotic pressure,Anasarca Local edema Lower extremity edema,Common Clinical Laboratory Assessment of Renal Disease,Cell protein cast glomerular tubular IVP CT renal biopsy MRI Cr Ccr GFR PSP Mosths,Renal disease,urinalysis,Renal function,Special examination,3. Treatment of Glomerular Disease,Removal causes,Corticosteroid,Immunosuppressive,Symptomatic and supporting,Primary Glomerula