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Dual-energy CT revisited with multidetector CT: review of principles and clinical applications,Muturay Karaaltncaba, Aykut Akta Turkish Society of Radiology 2010,Fig. 1. a, b. Axial DECT images acquired at the level of the pulmonary artery demonstrate the relationship between a Hounsfield unit measurement and kVp. Region of interest (ROI) measurements of the aorta on 140 and 80-kVp images yielded 312 H and 595 H, respectively. The iodine contrast density in the image was almost double that of the 80-kVp image.,Fig. 4. ad. Axial images of brain CTA and spectral curve for iodine (a and b) and water (c and d) images were acquired using gemstone spectral imaging. Note the hyperdense area on the water (virtual unenhanced) image, which is consistent with hemorrhage. The spectral data show the density of the hemorrhage (yellow), superior sagittal sinus (white and blue) and normal area on the iodine (b) and water images (d)for different keV. No differences in the spectral data for the hemorrhagic area are evident.,Fig. 6. a, b. Axial iodine map (a) and virtual non-contrast (b) images acquired using dualsource CT show an absence of enhancement and calcification within the solitary lung nodule on the right side.,Fig. 7. ac. Arterial-phase 4-chamber (a), delayedenhanced 4-chamber (b) and 2-chamber (c) 80-kVp DECT images were acquired by dualsource CT. Note the superior distinction of the apical thrombus from the viable myocardium on the delayed DECT images.,Fig. 8 Axial DECT image from the left ventricle acquired by gemstone spectral imaging without the administration of contrast shows a hyperdense appearance of the left ventricle myocardium. Spectral analysis of the myocardium (red, pink and blue circles), intercostal muscles (yellow) and subcutaneous fat shows an increased density of the myocardium in the lower keV spectrum compared to the spectral pattern observed for subcutaneous fat and intercostal muscles.,Fig. 9. ac. Coronal volume-rendered (a), MIP (b and c) and DECT Angiography images acquired by dual-source CT show dualenergy Bone removal (b) and calcific plaque removal (c).,Fig. 10. ac. Axial DECT image (a) acquired using gemstone spectral imaging without contrast administration shows the quantification of steatosis by the dual-energy methods. The spectral pattern of the steatotic (pink) area and hypersteatotic (green) area can be differentiated according to the mean Hounsfield unit values. The spectral pattern of the spared (blue) normal liver is reversed and reaches 65 H at 40 keV. Axial out-of-phase MRI at the same level confirms the findings obtained using DECT (b). Axial DECT image acquired using gemstone spectral imaging shows an increased density of the liver in the lower keV spectrum (reaching 120 HU at 40 keV), which is consistent with iron deposition (c). Note that the spectral curves for the normal liver and the liver with iron deposition are similar, but the mean H values in the latter are higher.,Fig. 11. af. DECT colonoscopy iodine (a, c, e) and virtual non-contrast (b, d, f) images acquired by dual-source CT (a, b) and gemstone spectral imaging (cf) show the absence of a polipoid lesion. Note the lack of FOV restriction on the images obtained by fast kVp switching (cf). The iodine DECT colonoscopy image (e) shows an absence of fluid enhancement in the right colon segments.,Fig. 12. ad. Coronal DECT images obtained by dual-source CT. A contrast enhancement in the septa of the left renal cystic lesion is evident on the iodine map (a). Note the absence of calcification on the virtual noncontrast image (b). An enhancement of the solid renal mass in the left lower pole is clearer on the iodine map (c) in comparison to the virtual non-contrast image (d).,Fig. 14. ad. Axial water (a), gray-scale iodine (b) and colored iodine (c) (70 keV) DECT images obtained by fast kVp switching show a left ovarian mass. Spectral curves (d) for the solid (red) and cystic (pink) parts of the ovarian tumor are evident.,Limitations of dual-energy MDCT,The major limitations of DECT are restrictions of the field of view (with dual-source CT), high radiation dose, noise in the 80-kVp images and the evaluation of patients with a high BMI. An increased radiation dose can be justified when unenhanced CT images are eliminated from the CT protocols. The use of iterative reconstruction techniques can facilitate the wider use of DECT applications by decreasing the noise and the radiation dose.,References,1 Karcaaltincaba, M, Aktas, A. Dual-energy CT revisited with multidetector CT: review of principles and clinical applications. Diagn Interv Radiol. 2010 . 2 Coursey, CA, Nelson, RC, Boll, DT, et al Dual-energy multidetector CT: how does it work, what

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