危重病的早期预警课件

ICU=重症医学？ 危重病的早期预警 浙江省人民医院ICU 孙仁华 内容 背景 危重病的早期预警 小结 什么叫重症医学? 早期发现并积极处理危重症 -提高抢救成功率的关键 ARDS ALI ARF AKI MOF MODS 病情的突然变化 -病情变化被突然发现 研究显示：那些没有经过心肺复苏就死亡的住院 患者中，约一半的患者在死亡前的24 h内具有可 逆的生命体征异常；80的院内心脏骤停的患者 在发生事件前8 h内已经出现了严重的生命体征的 异常 从不同部门入ICU患者死亡率的差别 普通病房入ICU患者的死亡率高于从急诊室、手 术室、麻醉复苏室入ICU者 早期、恰当的治疗可以有效提高抢救成功率，降 低致残率 现代医学专业细分化与患者高龄化和复杂化的矛 盾-发现延误、处理不当 Hillman KM等前瞻性研究了551例从不同科室入 ICU患者情况：90例来自普通病房，239例来自OR ，222例来自ED。普通病房入ICU患者APACHE II 评分21，OR 15，ED 19；死亡率分别为47.6%、 OR 19.3%、 ED 31.5%；入ICU前经历的不良事 件：普通病房72%、 OR 64.4%、 ED 61.8%。入 ICU前8小时常见的不良事件： hypotension (n=199), tachycardia n=73), tachypnoea (n=64), and sudden change in level of consciousness (n=42). Intensive Care Med (2002) 28:16291634 危重病的早期预警 早期预警（Early warning scoring system， EWS）主要适用于ICU外区域， 最早由英国 Morgan等提出，并得到广泛的认可与应用。也有 称physiological track and trigger warning systems (TTs) 具体评介方法并未统一，多达数十种，但多以简 单、常用生理参数为基础。 MEWS是比较常用的方法之一 Recommendation Multiple-parameter or aggregate weighted scoring systems used for track and trigger systems should measure: heart rate respiratory rate systolic blood pressure level of consciousness oxygen saturation temperature. NICE clinical guideline No. 50. London; 2007 Recommendation In specific clinical circumstances, additional monitoring should be considered; for example: hourly urine output biochemical analysis, such as lactate, blood glucose, base deficit, arterial pH pain assessment. NICE clinical guideline No. 50. London; 2007 危重病的早期预警 在EWS的基础上，国外许多医院成立： Critical Care Outreach Service (CCOS)， Medical Emergency Team (MET)，Rapid Response Teams等以提高危重病人的抢救 成功率。 改良早期危险评分（MEWS) Journal of Critical Care (2012) 27, 424.e7424.e13 Content of measurements. The combination (in white) of all measurements taken (N = 2688) is shown compared with the measurements with a positive MEWS (3 points) in black (n = 988). All possible combinations were analyzed, and those with a prevalence of 4% or more were included. BP indicates systolic blood pressure; Resp, respiratory rate; Temp, temperature; Sat, peripheral saturation with supplementary oxygen therapy Early Warning Score scoring system EWS 3 2 1 0 1 2 3 Pulse rate 51-100 101-110 111-130 130 BP (systolic) 200 Respiratory rate 30 Temperature 37.5 Consciousness A V P U EWS = Early Warning Score; BP = blood pressure; A= alert; V=responsive to voice; P=responsive to pain; U=unresponsive. Worried about patients condition: 1 point; Urine production below 75 ml during previous 4 hours: 1 point; Saturation below 90% despite adequate oxygen therapy: 3 points. january 2013 , vol . 71, No1 13 months (May 2010- May 2011),71,911 EWS values in the Medical Centre Alkmaar. 56% ( 40,183) on surgical wards, 44% (31,728) on medical wards Mortality rate as a percentage of admissions each year. Average values pre- and post- MEWS are shown along with P values M.S. Patel et al. Injury, Int. J. Care Injured 42 (2011) 14551459 The distribution of NEWS values and the relationship with each of the four outcomes studied. Smith GB, et al. The ability of the National Early Warning Score (NEWS) to discriminate patients at risk of early cardiac arres