课件：非霍奇金淋巴瘤(NHL).ppt

non-Hodgkin lymphoma non-Hodgkin lymphoma （NHLNHL） Song wenjingSong wenjing The department of pathologyThe department of pathology Introduction Introduction They are malignant tumors originating from They are malignant tumors originating from lymphoid tissue lymphoid tissue （B-cells and T-cells in B-cells and T-cells in different developed stagedifferent developed stage）. . Incidence: Incidence: HL, account for 8090% all HL, account for 8090% all lymphomas.lymphomas. Site: lymph nodes(2/3)Site: lymph nodes(2/3)； extranodal lymphoid tissue(1/3).extranodal lymphoid tissue(1/3). The difference between HL and NHL about clinic-The difference between HL and NHL about clinic- pathological characteristicspathological characteristics HLNHL Site intranodeIntranode and extranode Morphology multiplicity *R-S cell unitary Metastasis Anatomic continuously skipping Prognosis well poor IntroductionIntroduction The process of LC differentiationThe process of LC differentiation Morphology Morphology Multiple lymphomas of stomach Morphology Morphology Precursor B-cell and T-cell neoplasm Precursor B-cell and T-cell neoplasm （Acute Lymphoblastic Leukemia /LymphomaAcute Lymphoblastic Leukemia /Lymphoma） Introduction Introduction Morphology Morphology 前体前体 B淋巴母细胞淋巴瘤：胞浆稀少；核较小、近圆形，染色质淋巴母细胞淋巴瘤：胞浆稀少；核较小、近圆形，染色质 细致、细颗粒状。细致、细颗粒状。 前体前体 T淋巴母细胞白血病（骨髓活检切片）：淋巴母细胞大小不淋巴母细胞白血病（骨髓活检切片）：淋巴母细胞大小不 等，核迂曲。等，核迂曲。 Clinic Clinic Peripheral mature B cell neoplasmaPeripheral mature B cell neoplasma Small lymphocyte lymphomaSmall lymphocyte lymphoma (Chronic lymphocyte leukemia)(Chronic lymphocyte leukemia) Introduction Introduction Morphology Morphology B-CLL/SLL Small lymphocyte lymphoma B-cell chronic lymphocytic leukemia /small lymphocytic lymphoma Clinic Clinic Follicular LymphomaFollicular Lymphoma Introduction Introduction Morphology Morphology Follicular lymphoma of ileum Clinic Clinic Diffuse large B-cell lymphomaDiffuse large B-cell lymphoma Morphology Morphology Diffuse large B-cell lymphoma (centroblastic variation) Diffuse large B-cell lymphoma (immunoblastic variation) Clinic Clinic Burkitt lymphomaBurkitt lymphoma Introduction Introduction Morphology Morphology Ileocecal Burkitt lymphoma Clinic Clinic Burkitt Lymphoma Marginal zone lymphoma Marginal zone lymphoma Mucosa Associated Lymphoid Tissue, MALTMucosa Associated Lymphoid Tissue, MALT -oma -oma Introduction Introduction PositionPosition Morphology Morphology Stomach MALT-omaStomach MALT-oma Breast MALTomaBreast MALToma Parotid MALT-omaParotid MALT-oma Endometrial MALT-omaEndometrial MALT-oma Multiple Myeloma Multiple Myeloma Peripheral T-cell and NK cell NeoplasmsPeripheral T-cell and NK cell Neoplasms Peripheral T-cell lymphoma, Unspecified Peripheral T-cell lymphoma, Unspecified Morphology Morphology Peripheral T-cell lymphoma Peripheral T-cell lymphoma (unspecified)Peripheral T-cell lymphoma (unspecified) Peripheral T-cell lymphoma (unspecified)Peripheral T-cell lymphoma (unspecified) Extranodal natural killerExtranodal natural killer /T-cell lymphoma /T-cell lymphoma Introduction Introduction Extranodal natural killer/T-cell lymphoma add：Complications of lymphoma lymphoma invade Compress,invasion marrow spleen immune dysfunction marrow inhibition autoimmune function hemolysis anemia infection Myeloid neoplasmMyeloid neoplasm Histocytic neoplasmaHistocytic neoplasma Leukemoid reactionLeukemoid reaction 后面内容直接删除就行后面内容直接删除就行 资料可以编辑修改使用资料可以编辑修改使用 资料可以编辑修改使用资料可以编辑修改使用 主要经营：网络软件设计、图文设计制主要经营：网络软件设计、图文设