第六届全国生物信息学与系统生物学学术大会

第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会会议时间：2014年10月6日 9日会议地点：南京市中山东路307号钟山宾馆（江苏省会议中心）会议日程概要时 间内 容地 点10月6日10:00 22:00会议报到中山东路307号钟山宾馆大厅（江苏省会议中心）20:00功能基因组信息学与系统生物学分会理事会310会议室10月7日上午开幕式，大会报告三楼大会堂下午分会场报告307、308、309会议室10月8日上午大会报告三楼大会堂下午分会场报告307、308、309会议室晚上墙报；青年沙龙金陵厅；307会议室10月9日上午大会报告，闭幕式三楼大会堂下午离会或南京观光会议期间联系：侯谢建孙 议 日 程一、10月7日上午, 三楼大会堂时间开幕式主持人8:15 8:351. 领导、专家致辞2. 大会组织委员会主席致辞3. 大会秘书长简要报告会议的筹备陈润生8:35 9:05全体参会人员合影大会特邀报告时间报告人报告题目主持人9:10 9:55郝柏林古菌亲缘关系和分类系统：16S rRNA序列分析和全基因组方法的比较陈润生9:55 10:10茶歇10:10 10:55刘小乐Computational Analysis of Genome-wide CRISPR-Cas9 Knockout Screens孙之荣10:55 11:40徐 鹰Elucidation of Cancer Mechanisms through Data Mining: an introduction to a new evolutionary framework to study cancer二、主题报告、专题报告（一）10月7日下午，307会议室主题报告（一）生物大分子结构与功能研究，大数据时代的测序技术发展与应用主持人：李前忠时间报告人报告题目工作单位1:30 1:55王 炜金属离子调控的蛋白质折叠和功能运动南京大学1:55 2:20钟伯雄iTRAQ-based proteomics analysis of the molecular mechanism associated with the difference of silk production in silkworm浙江大学2:20 2:45彭绍亮Computational Biology and Big Data on TianHe Supercomputer国防科技大学2:45 3:10季星来Genome projects of the nematode-trapping fungi云南大学3:10 3:35蒋太交流感分子演化模拟中科院生物物理所3:35 3:45茶歇专题报告（一）生物信息学的新概念、新思想和发展趋势主持人：蒋太交3:45 4:05彭 城Chromatin three-dimensional organization analysis and modeling华中农业大学4:05 4:25宁尚伟LincSNP: a database of linking disease-associated SNPs to human large intergenic non-coding RNAs哈尔滨医科大学4:25 4:45张 焱Prediction of New Candidate Genes Involved in Selenium Metabolism in Eukaryotes中科院上海生科院4:45 5:05鲁兴华Identification of a p53-centered pathway reveals a strategy for targeting p53 mutations匹兹堡大学（美国）5:05 5:25杨 冬New Insights into the Relationship between Evolution and Development in the View of Genomic Complexity Realization北京蛋白质组研究中心5:25 5:45朱山风MHC2SKpan: A novel kernel based approach for pan-specific MHC class II peptide binding prediction 复旦大学三、主题报告、专题报告（二）10月7日下午，308会议室主题报告（二）生物大分子结构与功能研究主持人：张晓华时间报告人报告题目工作单位1:30 1:55肖 奕Prediction of Tertiary Structures of RNA molecules and their Complexes华中科技大学1:55 2:20来鲁华Designing Functional Proteins北京大学2:20 2:45刘海燕Computational Protein Design with a Comprehensive Statistical Energy Function and Boosted by an in vivo Experimental Approach中国科技大学2:45 3:10龚海鹏Exploring the mechanism of the Na+/K+ selectivity in mammalian voltage-gated sodium channels清华大学3:10 3:35魏冬青Free Energy Calculations of Membrane Systems and CADD上海交通大学3:35 3:45茶歇专题报告（二）生物大分子结构与功能研究主持人：季星来3:45 4:05彭友松Epistasis on Hemagglutinin Contributes Significantly to the Antigenic Evolution of Influenza A( H3N2) virus湖南大学4:05 4:25柳树群Characterizing the Molecular Motions and Free Energy Landscapes of HIV-1 gp120云南大学4:25 4:45张子丁Structural Propensities of Human Ubiquitination Sites中国农业大学4:45 5:05祝小雷Large-scale Binding Ligand Prediction by Improved Patch-based Method Patch-Surfer2普渡大学（美国）5:05 5:25吕守芹Structural bases for conservative Leu (Ile) site of the CD loop induced gating kinetics difference of Kir channel中科院力学所5:25 5:45朱建伟Improving Protein Fold Recognition Via Identifying Common Protein Structure Framework中国科学院大学四、主题报告、专题报告（三）10月7日下午，309会议室主题报告（三）医学系统生物学及转化医学主持人：梁艳春时间报告人报告题目工作单位1:30 1:55陈洛南Detecting un-occurred disease states for complex diseases by dynamical network biomarkers中科院上海生科院1:55 2:20李 霞Non-coding RNAs Computational Systems Biology for Major Diseases哈尔滨医科大学2:20 2:45沈百荣Biomarker discovery for complex diseases based on translational biomedical informatics苏州大学2:45 3:10赵兴明Prediction of cancer associated miRNAs based on gene expression同济大学3:10 3:35刘 峰P53 dynamics mediate the cellular response to DNA damage南京大学3:35 3:45茶歇专题报告（三）医学系统生物学及转化医学主持人：王秀杰3:45 4:05阚显照Molecular evolution of genomic recombination and reassortment: a case study of H6N1, MERS-CoV and avian mtDNA安徽师范大学4:05 4:25赵 倩MethylPurify: tumor purity deconvolution and differential methylation detection from tumor DNA methylomes同济大学4:25 4:45周丰丰Constraint Programming based Biomarker Optimization中科院深圳先进技术研究院4:45 5:05李彭平在实性假乳头状肿瘤转录调控网络中识别该疾病相关基因南京大学5:05 5:25蔡梅春Prediction of Renal Disorders Based on Similarity of Molecular Fingerprint厦门大学5:25 5:45刘新华Computing the Phenotype Similarity Based on OMIM Database and MESH Vocabulary天津医科大学五、10月8日上午, 三楼大会堂大会特邀报告时间报告人报告题目主持人8:30 9:15欧阳颀能量耗散与振荡系统相位稳定性的关系研究刘小乐9:15 10:00韩敬东Alu Repetitive Elements as Proto-Enhancers10:00 10:15茶歇10:15 11:00黄海艳New gene coexpression measures in large heterogenous samples using count statistics孙 啸11:00 11:45Sheng ZhongCell fate inclination within 2-cell and 4-cell mouse embryos revealed by single-cell RNA sequencing6、 主题报告、专题报告（四）10月8日下午，307会议室主题报告（四）大数据时代的测序技术发展与应用, 生物网络与系统的构建及功能分析主持人：魏冬青时间报告人报告题目工作单位1:30 1:55陆祖宏Development of Single DNA Sequencing and Its Opportunities in Genomic and Medical Researches东南大学/北京大学1:55 2:20于 军The Complexity of Mammalian Transcriptomes and a Need for a Pan-mammalian Transcriptome Project中科院2:20 2:45黄海亮Moving beyond GWAS: fine-mapping of the genetic risk loci underlying human disorders麻省总医院（美国）2:45 3:10李英睿Life is a Game of Evolution华大基因3:10 3:35邓海腾Systematic Analysis of HSP60-Mediated Protein Interaction Network and Metabolic Pathways清华大学3:35 3:45茶歇专题报告（四）生物网络与系统的构建及功能分析主持人：于 军3:45 4:05薛 宇Phosphoproteomics-based network medicine华中科技大学4:05 4:25李伍举Genome-wide Study of Protein-RNA interactions in Escherichia coli军事医学科学院4:25 4:45杨雪瑞Context-specific DNA Methylation Defines Dynamics of Transcription Regulatory Networks in Cancers清华大学4:45 5:05徐自祥RegKnock: identifying gene knockout strategies for microbial strain optimization based on regulatory and metabolic integrated network中科院天津工业生物技术所5:05 5:25贾 晨Overshoot in biological systems modeled by master equations: A physical perspective北京大学5:25 5:45郭 静Mathematical modeling for embryonic stem cell reprogramming by lineage specifiers and pluripotency factors南洋理工大学（新加坡）7、 主题报告、专题报告（五）10月8日下午，308会议室主题报告（五） 生物信息学的新概念、新思想和发展趋势主持人：沈百荣时间报告人报告题目工作单位1:30 1:55王存新Molecular Modeling Studies on Interactions among Persistent Organic Pollutants and Proteins北京工业大学1:55 2:20张成岗为什么在组学和大数据时代也仍然难以研发出有效解决疾病防诊治的新药好药？兼论生物信息学的发展方向军事科学医学院2:20 2:45张晓华Big Data and its Application in the Pharmaceutical Industry默沙东研发中心（中国）2:45 3:10陈 铭RiceNet, an integrative approach for genome wide metabolic network reconstruction of rice浙江大学3:10 3:35梁艳春Identification for Cancer Biomarker through Computational Technology吉林大学3:35 3:45茶歇专题报告（五）生物大分子结构与功能研究主持人：钟伯雄3:45 4:05李明锟Variation of mtDNA in different tissues德国马普所4:05 4:25龚新奇New function discovery using Hausdorff-based protein 3D structural comparison中国人民大学4:25 4:45于家峰A hybrid pipeline for comprehensive annotation of the protein coding genes in prokaryotic genomes德州学院4:45 5:05何顺民piRNA-mediated cleavage of messenger RNAs and long non-coding RNAs中科院动物所5:05 5:25汪小我Quantitative modeling of microRNA-mediated regulation on competing endogenous RNAs清华大学5:25 5:45高 峰Comprehensive Analysis of Essential Genes Based On an Update of the Database of Essential Genes天津大学8、 主题报告、专题报告（六）10月8日下午，309会议室主题报告（六） 转录调控与表观遗传修饰主持人： 李 霞时间报告人报告题目工作单位1:30 1:55孙 啸Nucleosome occupancy patterns around different gene regulatory sites东南大学1:55 2:20张 勇Revealing novel functional mechanisms of chromatin regulators using high-throughput data mining同济大学2:20 2:45李 立The role of architectural proteins in the 3D organization of the genome艾默里大学（美国）2:45 3:10王秀杰Broad existence of pluripotency factor regulated transcript isoforms with stage-specific alternative first exons (SAFE) in mouse embryonic stem cells中科院遗传与发育生物学所3:10 3:35李前忠The theoretical study of histone modification and its effects on gene expression in the embryonic stem cell内蒙古大学3:35 3:45茶歇专题报告（六）转录调控与表观遗传修饰，大数据时代的测序技术发展与应用主持人：张 勇3:45 4:05蔡 禄The regulated n