镇痛实验报告.doc

123 2012021320 1. 2. 1. 632. 1#, 2# 0.1ml/10g3#, 4# 0.1ml/10g5#, 6# 0.1ml/10g150.1ml/10g3. 204. 23456 0 10 0 17 13 0 2 0 3 2 3 dolantinrotundine p>0.0515min163.1%,4714.39 s100%3412.47sp<0.0530min33.1%249.72 s93.8%3815.00 sp<0.05,30min22.5%2213.06 s70.2%3517.64 sp<0.05 1. 1.1. 2025 1.2 1.3 0.25%0.25% 1.4 550.1oc1.5 330 1.60.25%0.1ml/10g 0.25%0.1ml/10g 0.1ml/10g1.7 153060min 1.8 ?xst 1.9 -=2. 1 1* 100%1. (n=9) 1 2 3 4 5 6 7 8 9 x s() 0 18 26 17 21 15 20 18 15 21 1915 23 27 17 21 16 17 11 20 15 1930 14 27 14 14 10 21 15 18 11 1660 21 22 17 17 14 18 13 21 12 17() 0 16 22 23 10 13 25 22 13 16 1815 48 60 26 26 60 43 38 60 60 47 14.33.46 4.75 5.29 3.67 5.33 191916-15.08- 9.4/17189 47xs %()60 23 55 25 14 18 14 15 16 16 22 13.06 2213.060 28 14 20 24 15 23 15 19 20 20 4.68 204.68 /15 60 33 23 21 24 45 30 32 40 34 12.47 3412.47 10030 60 40 32 35 19 51 25 25 58 38 15.00 3815.0017.64 3517.64. 60 60 35 28 28 13 43 14 22 60 3430 14 39 40 27 20 18 21 19 15 24 9.72 249.7214.39 163.13.46 4.75 5.29 3.67 5.3333.1 22.5 93.8 70.21 * p<0.05,* p<0.05,*p<0.05 vs control group* p<0.05 vs rotundine group; #p<0.05 vs dolantin group ;*p>0.05 vs rotundine group15min3015min4714.39 s3.3.1 p<0.0515minp<0.05,30minp<0.0560minp>0.0515min15min30min60min510mg61 ,1/71/10160100mg2513.2 . 3.2.1ppdolantindolantinpca2+k+ 3.2.2dad2damrna1 . . . 2004;351,356,357 .2 . . . 200929(5):3193203 . . . 29720067: 713714.4 . . . 2004257258()1 215min15min500ml1ml0.2%1ml12.5ml0.7%2%1 333110.1ml/10g0.1ml/10g0.1ml/10g30min0.7%0.1ml/10g2 15min15min3 15min11 1 22 p>0.0515min267%,106%(p<0.0530min244%142%p>0.0560min104%58%p<0.05 2.5g/l dolantin2.5g/l rotundine sulfate 1550.1230132i.p.dolantin25mg/kg(2.5g/l 0.1ml/10g)i.p. rotundine 25mg/kg (2.5g/l 0.1ml/10g)i.p. 0.1ml/10g15min30min60min60603() 1. p>0.052. 15min267%,55.29.48s106%35.6017.34sp<0.053. 30min244%51.810.47 s142%41.7015.38sp>0.054. 60min104%30.7015.67 s58%27.3018.02sp<0.05.5. 1. 2.