抗生素英文课件精品 antibioticsand antibiotic

AntibioticsAntibioticresistance Animationsfromlecture SynthesisofPeptidoglycan Duringnormalbacterialgrowth bacterialenzymescalledautolysinsputbreaksinthepeptidoglycaninordertoallowforinsertionofpeptidoglycanbuildingblocks monomersofNAG NAM peptide Transpeptidaseenzymesjointhepeptideofonemonomerwiththatofanotherinordertoprovidestrengthtothecellwall GaryKaiserhttp www cat cc md us courses bio141 lecguide unit2 control ppgsynanim html AnimationIllustratingtheRoleofPenicillinsinBlockingTranspeptidaseEnzymesfromAssemblingthePeptideCross LinksinPeptidoglycan GaryKaiser Penicillinsandcephalosporinsbindtothetranspeptidaseenzymeandblocktheformationofthepeptidecross links Thisresultsinaweakcellwallandosmoticlysisofthebacterium Proteinsynthesisinhibitors Inhibittranslocation preventribosomefrommovingtothenextcodon Inhibitpeptide bondformationBlockthegrowingchainbylinkingtothepeptideInhibitbindingofaa tRNAs chargedtRNAs Causemisreadingofcodons Initiationoftranslationinbacteria http www cat cc md us courses bio141 lecguide unit2 control translat html AminoglycosidesInterferingwiththeTranslocationoftRNAfromtheA sitetotheP site Aminoglycosides streptomycin neomycin netilmicin tobramycin gentamicin amikacin etc http student ccbcmd edu courses bio141 lecguide unit2 control aglyconoAP anim html AnimationofTetracyclinesBlockingTranslation http student ccbcmd edu courses bio141 lecguide unit2 control tetres html ModeofActionofMacrolidesinBlockingTranslation BlockingPeptidyltransferase macrolides erythromycin azithromycin clarithromycin dirithromycin troleandomycin etc bindtothe50Ssubunit Animation Mechanismsofantibiotics Antibiotics Methodsofcontrolhttp student ccbcmd edu courses bio141 lecguide unit2 control antibio htmlAntibioticsthatinhibittranslationhttp student ccbcmd edu courses bio141 lecguide unit6 genetics protsyn translation translation html Bacterialresistancetoantibiotics ProducinganEnzymetoDestroyorInactivatetheAntibiotic http www cat cc md us courses bio141 lecguide unit4 genetics resist enz html GaryKaiser Bacterialresistancetoantibiotics ProducinganAlteredTargetSitetowhichtheAntibioticnoLongerBinds http www cat cc md us courses bio141 lecguide unit4 genetics resist altrib html GaryKaiser Bacterialresistancetoantibiotics ProducinganAlteredPorinintheOuterMembraneofaGram NegativeCel