高血压和肥胖课件幻灯

HypertensionandObesityinChina ProfessorsChenChunming ZhaoWenhua OnbehalfoftheWorkingGrouponObesityinChina ILSIFocalPointinChina ChineseCenterforDiseaseControlandPrevention BeijingChina PartI HypertensionriskatBMIandwaistcircumference WC levels InternationalLifeScienceInstituteFocalPointinChina ILSIFP China establishedaWorkingGrouponObesityinChina WGOC in2000 WGOCorganizedametaanalysisonthedatafrom13bigscalecross sectionalsurveysince1990 underaprotocolforanalysisdatacollectedamong239 972adultsaged20 70wereincluded Datasourceandanalysis Analysisondiseaserisksfactors suchashighbloodpressure diabetesincludingfastbloodglucose FBG serumcholesterol HDL C triglycerides TG inrelationtoBMIandwaistcircumference WC wascarriedout Metaanalysisofcohortstudiescovered4datasetswith76 227adultsubjectswasdone theendpointsaretotalmortality mortalityofcoronaryheartdisease strokeandcancer aswellasincidencesofcoronaryheartdiseaseeventsandstrokeevents Partoftheresultsispresentedhere Theresultsontheprevalenceofhypertension andclusteringofriskfactors highbloodpressure diabetesincludingfastbloodglucose FBG serumcholesterol HDL triglycerides andBMIorwaistcircumference WC waspresentedasfollows BMIandhighbloodpressure Male Male Female TheprevalenceofhypertensionincreasedwithincreasinglevelsofBMI WCandhighbloodpressure Male Female TheprevalenceofhypertensionincreasedwithincreasinglevelsofWC BMIandriskfactorclustering Male Female TheprevalenceofclusteringofriskfactorsincreasedwithincreasinglevelsofBMI WCandriskfactorclustering Male Female TheprevalenceofclusteringofriskfactorsincreasedwithincreasinglevelsofWC Populationattributableriskpercent ofhypertensionatBMIlevelsMaleFemaleOR PARPORPARPBMI 243 6945 92 7638 4BMI 283 1711 52 6112 7 Ageadjusted Populationattributablerisk ofhypertensionbeyondWCcutoffsOR PARPMenWC 85cm3 4441 3WomenWC 80cm3 3042 8 Ageadjusted PartII CorrelationanalysisofWC BMIandbloodpressure DatasourceandanalysisAstudywasconductedinAnhuiandHenanprovincesin1996byChenJunshiandZhaoWenhua Totally11 815ruralresidentsaged40 79weresurveyedandinformationincludedbloodpressure high weightandwaistcircumference dietandbloodsamplewerecollected TherelationshipbetweenWC BMIandbloodpressurewasanalyzed CorrelationanalysisofWC BMIandbloodpressure male CorrelationanalysisofWC BMIandbloodpressure Female Prevalence ofhypertensionbyBMIgroup male BMI HP BMI WCandPrevalenceofHypertension Prevalence ofhypertensionbyBMIgroup Female BMI HP Prevalence ofhypertensionbyWCgroup male Prevalence ofhypertensionbyWCgroup Female CombinationofBMIandWCinrelationtohypertensionprevalence BMI CombinationofBMIandWCinrelationtohypertensionprevalence Male CombinationofBMIandWCinrelationtohypertensionprevalence Female BMI WhenWC 75cm prevalenceofhypertensionincreasedsignificantly P 0 05 Hypertensionprevalence atvariousWClevelswithBMI 24 male Hypertensionprevalence atvariousWClevelswithBMI 24 female AtBMI 24 WC 80 male WC 75 female prevalenceorhypertensiondramaticallyincreased p 0 05forallgroups PartIII SummaryandConclusionDataindicatedapplicationofCombinationofBMIandWCwillbethebestpredictorforhypertensionrisk recommendationwasmadetosetoverweightcutoffatBMI 24 WC 85formenand 80cmforwomenasnormal Applyingtheclassification overweight BMI 24 prevalenceis30 40 ifBMIcouldbecontrolledunder24 38 45 hypertensionofth