上海交通大学药学网络教育毕业考试10秋药专练习卷1-Microsoft-Word-文档.doc

上海交通大学网络学院医学院分院2010（春、秋）年级毕业理论综合考试练习卷（1）专业：药学（专科）一、英语：(30%)I Vocabulary & StructureDirections: There are 20 incomplete sentences in this part. For each sentence there are four choices marked A, B, C, and D. Choose the one that best completes the sentence.1. One of the boys speaks _ but not very correct English.A. frequent B. flexible C. fluent D. fluid2. The boss told his secretary to _ his order without delay.A. hold up B. talk over C. carry out D. set aside3. Mr. Black was in the _，standing there dumbfounded，not knowing what to do A. dark B. dusk C. dawn D. dam4. The spending cuts made it impossible to fill the posts left _ by retired teachers. A. depressed B. jealous C. vacant D. dissatisfied 5. _ has been discovered that the two countries are making secret contact with each other to normalize their relationship.A. What B. That C. All D. It6. We should see ourselves as part of nature rather than in _ with it.A. argument B. connection C. conflict D. crash7. Tom made his final _ to buy a country house on his own hometown. A. impulse B. ambition C. decision D. loneliness8. They all returned to the village, _ that the danger was over.A.convincing B.convinced C. to convince D. having convinced9. I was shocked by the conditions in the factory, which _ definite health and safety hazards. A. constituted B. masked C. enclose D. consolidated10. Young pilots should _ doing too many new things in one flight; i.e. do not fly a new type of aircraft on an unfamiliar airfield.A.avoid B. manage C. decrease D.deny11. Our city has many buildings which _ those found in the West.A. are being made of B. resemble C. accumulate D. locate12. I was _ at the number of people who did not know that George Washington is called the Father of His Country.A. ignorant. B. blessed C. amazed D. content13. Dont _ the others, because they have to leave now.A. pull into B. hold up C. take over D. bring about14In a small enterprise or department, management by inertia (惰性) is a _ disease. A. current B. deadly C. radical D. typical 15. _ 50 years since my parent got married.A. It is B. There are C. It was D. There have been16. The Indians have their rights, so the Americans who forced them off their land _ have done that!A. mustnt B. wouldnt C. shouldnt D. couldnt17. Regular review is important. Devote some time during each study hour toreviewing material _ learned.A. scarcely B. eventually C. previously D. exactly18. On that holiday children like to be dressed up _ strange clothes and knock at every door to ask for candy.A. by B. with C. on D. in19. People are clearing the snow from the road _ they can walk safely.A. lest B. in spite of C. Since D. so that20. Its a pity that the device used _ counting money doesnt work now.A. at B. by C. for D. to21. However, promotion is not always easy to achieve, as I _ when I firstreturned to work in 1977 after my degree course. A. turned out B. acted out C. found out D. sought out 22. Why dont you _ the break to have a cup of coffee and relax yourself.?A. look into B. hold up C. come up with D. take advantage of23. We had better move forward, for it will not do us any good to _ the past.A. shrug off B. dwell on C. live on D. single out 24. Had she been given some information, she _ the question.A. would answer B. could answer C. could have answered D. answered25. I was not satisfied with the result, _.A. my parents did not, either B. not satisfied by my parents, eitherC. nor my parents were satisfied D. nor were my parentsIIReading Comprehension Directions: There is a passage in this part. The passage is followed by some questions or unfinished statements. For each of them there are four choices marked A, B, C, and D. You should choose the best answer to each question based on the passage.Passage :What makes money valuable? Why is a piece of paper marked $10 worth more than one marked $1? You could say there is no reason. Its true that a special kind of paper is used to make dollar bills, and they are pretty, but thats not what makes them valuable. The real reason money is valuable is that everyone believes it is.Ancient economies had no paper money or coins. Some used barter trading one thing for another. Others used all kinds of objects as money. Any object would do, as long as there was not an unlimited amount of it. Animals or metals were popular, and so were manufactured products like jewelry or weapons. Wealth in ancient Greece was measured in tools or cattle. This kind of money had two purposes. First, it was useful in itself. Tools and cattle can be used for farming. And second, it was a way to symbolize (象征) and measure value. A house, for example, would be valued at a certain number of tools or cattle. This greatly simplified trade. Other societies used money that was totally symbolic. For instance, American Indians used wampum, which is made from seashells. And until recently on the Pacific island of Yap, people used large stone discs as money. In most places these types of money died out because more practical forms of money were invented. People started using precious metals, such as gold and silver, that were easier to carry around than tools or stones. And in the eighteenth century, paper money was introduced. At first people were suspicious of the new currency, but they came to accept it because the government or bank issuing it would exchange an equal amount of gold for the paper. A $10 bill really was worth $10 0f gold. But now, people are used to the idea that the government doesnt have to back its money with gold. Everyone believes that a $10 bill is worth $10 and that is good enough. But if, for some reason, people ever lost faith in paper money, ten dollars wouldnt be worth the paper its printed on.26. Which of the following in NOT mentioned as the first kind of money?A. AnimalsB. Houses C. Metals D. Weapons27. The pronoun it (line3, para. 2) refers to _.A. money B. wealth C. farm work D. the object chosen as money28. Tools and cattle were used as money because _.A. they could be found in every familyB. they were useful and symbolized valueC. they were easier to carry aroundD. they were the only wealth in ancient times29. The word “precious” (line2, para.3) is closest in meaning to _.A. valuable B. popular C. large D. heavy30. People were suspicious of paper money most probably because _.A. paper is not as useful as toolsB. paper had no value of its ownC. paper was just invented and new to peopleD. paper was under the control of the government二、药品质量与检验 (35%)：A型题（在一组备选答案中，选择一个最佳答案）：31药品杂质限量是指：A、药物中所含杂质的最小容许量 B、药物中所含杂质的最大容许量C、药物中所含杂质的最佳容许量 D、药物的杂质含量32砷盐检查法中，在检砷装置导气管中塞入醋酸铅棉花的作用是：A、吸收砷化氢 B、吸收溴化氢 C、吸收硫化氢 D、吸收氯化氢33检查药品中的铁盐杂质，所用的显色试剂是：A、AgNO3 B、H2S C、硫氰酸铵 D、BaCl2 34用TLC法检查特殊杂质，若无杂质的对照品时，应采用：A、内标法 B、外标法 C、峰面积归一化法 D、高低浓度对比法35少量氯化物对人体是没有毒害作用的。药典规定检查氯化物杂质主要是因为它： A、影响药物的测定的准确度 B、影响药物的测定的选择性C、影响药物的测定的灵敏度 D、影响药物的纯度水平36中国药典检查残留有机溶剂采用的方法为：A、TLC法 B、HPLC法 C、UV法 D、GC法37氧瓶燃烧法破坏有机含溴/碘化物时，吸收液中加入以下何种物质，可将Br2或I2还原成离子？A、硫酸肼 B、过氧化氢 C、硫代硫酸钠 D、硫酸氢钠 38准确度表示测量值与真值的差异，常用（ ）反映。A、日内RSD B、回收率 C、标准对照液 D、空白实验 39非水液中滴定巴比妥类药物，其目的是：A、巴比妥类的Ka值增大，酸性增强 B、增加巴比妥类的溶解度C、使巴比妥类的Ka值减少 D、除去干扰物的影响40巴比妥类药物与银盐反应是由于结构中含有：A、43酮基 B、芳香伯氨基 C、酰亚氨基 D、酚羟基41根据巴比妥类药物的结构特点可采用以下方法对其进行定量分析，其中不对的是： A、三氯化铁比色法 B、溴量法 C、紫外分光光度法 D、酸碱滴定法 42下列哪个药物不能用重氮化反应？A、盐酸普鲁卡因 B、对乙酰氨基酚 C、对氨基苯甲酸 D、乙酰水杨酸 43抗生素原料的含量测定各国药典大多采用： A、容量分析法 B、HPLC法 C、TLC法 D、微生物检定法 44抗生素类药物的活性采用：A、百分含量 B、标示量百分含量 C、效价 D、浓度 45汞量法测定青霉素时较碘量法的优点是：A、不需标准品作对照 B、不需要做空白 C 、汞可直接与青霉素作用，无需水解 D、反应更加迅速 46不属于氨基糖甙类抗生素的是：A、红霉素 B、巴龙霉素 C、庆大霉素 D、卡那霉素 47对于平均片重在0.30g以下片剂，我国药典规定其重量差异限度为： A、3% B、5% C、7.5% D、10% 48下列关于溶出度的叙述错误的是：A、溶出度检查一般主要适用于难溶性药物 B、溶出度检查法分为蓝法和浆法等C、溶出度检查法规定的温度一般为37 D、溶出度与体内的生物利用度直接相关49复方阿司匹林片中咖啡因的含量测定方法除色谱法外，可为：A、滴定法 B、剩余碘量法 C、配合滴定法 D、银量法 50中药制剂分析的一般程序为：A、取样鉴别检查含量测定写出检验报告B、检查取样鉴别含量测定写出检验报告C、鉴别检查取样含量测定写出检验报告D、检查取样含量测定鉴别写出检验报告51药物不纯，则熔距：A、增长 B、缩短 C、不变 D、消失52 在液相色谱中，为了改变色谱柱的选择性，可以进行如下哪些操作？ A、改变流动相的种类或柱子 B、改变固定相的种类或柱长C、改变固定相的种类和流动相的种类 D、改变填料的粒度和柱长 53 高效液相色谱、原子吸收分析用标准溶液的配制一般使用：A、去离子水 B、国标规定的三级水C、不含有机物的蒸馏水 D、无铅(无重金属)水54光学分析法中, 使用到电磁波谱, 其中可见光的波长范围为：A、10400nm B、400750nm C、0.752.5mm D、0.1100cm55电磁辐射的微粒性表现在哪种性质上？ A、能量 B、频率 C、波长 D、波数56原子吸收光谱测铜的步骤是：A、开机预热设置分析程序开助燃气、燃气点火进样读数B、开机预热开助燃气、燃气设置分析程序点火进样读数C、开机预热进样设置分析程序开助燃气、燃气点火读数D、开机预热进样开助燃气、燃气设置分析程序点火读数57我们国家的药品命名原则是哪个部门制定的？A、国家食品药品监督管理局 B、中国药品生物制品检定所C、国家药典委员会 D、国家药品评审中心58药品必须从允许药品进口的口岸进口，并由进口药品的企业向口岸所在地药品监督管理部门登记备案。海关放行凭药品监督管理部门出具的：A、进口药品通关单 B、进口药品证书C、进口许可证 D、进口药品注册证书59下列属于假药的是：、改变剂型或改变给药途径的药品、擅自添加着色剂、防腐剂、香料、矫味剂及辅料的、超过有效期的、以非药品冒充药品或者以他种药品冒充此种药品的60国务院药品监督管理部门的职责不包含下列哪项？A、主管全国药品监督管理工作B、配合国务院经济综合主管部门执行国家制定的药品行业发展规划和产业政策C、监督管理药品价格D、组织药典委员会，负责国家药品标准的制定和修订。61广东省内药品生产企业的药品生产许可证由（ ）批准发给。A、省质量技术监督部门 B、省药品监督管理部门 C、省工商行政管理部门 D、国家药品监督管理部门62药品的法定名称是指：A、专利名 B、通用名 C、化学名 D、商品名 63含量测定方法选择方法的基本原则： A、化学原料药首选酶法 B、化学原料药首选容量分析法C、制剂首选容量分析法 D、酶类药物首选容量分析法64注射剂无菌的概念是：A、不含任何活的细菌 B、不含任何活的真菌 C、不含任何活的微生物 D、不含任何致病菌65含量限度是指按规定的测定方法测得本品应含“有效物质”的限度。为了能正确反映药品的含量，以下哪一项不正确？A、换算成干燥品的含量；B、按检查项下所规定的“干燥失重”或“水分”分别写成“按干燥品计算”或“按无水物计算”；C、按临床使用剂量标示； D、抗生素生化药物一般可按效价表示； 三、药物化学 (35%)：A型题（在一组备选答案中，选择一个最佳答案）：66下列哪项不是药物化学的研究内容？A、 寻找新的给药技术和方法 B、研究药物的结构和理化性质间的关系C、研究药物的结构和生物活性间的关系 D、为药物的结构修饰、剂型选择奠定化学基础67利多卡因比普鲁卡因作用时间长的主要原因是：A、普鲁卡因有芳香伯胺结构 B、普鲁卡因有酯基C、利多卡因有酰胺结构 D、酰胺键比酯键不易水解68下图为局麻药基本结构，则局麻作用最强的X为：A.、-O- B、-NH- C、 -S- D、 -CH2- 69异戊巴比妥不具有下列哪个性质？ A、弱碱性 B、加入过量的AgNO3溶液，可生成银盐沉淀C、与吡啶-硫酸铜反应生成紫色 D、 钠盐溶液易水解70具有下列结构的药物是：A、阿米替林 B、氟哌啶醇 C、氯丙嗪 D、地西泮71由巴比妥类药物结构改造获得的抗癫痫药物，结构特征属于： A、七元亚胺内酰胺 B、环内酰脲 C、大环内酰胺 D、二苯并氮卓72盐酸氟西汀属于哪一类抗抑郁药物？A、去甲肾上腺素重摄取抑制剂 B、单胺氧化酶抑制剂C、阿片受体抑制剂 D、5-羟色胺受体抑制剂73吩噻嗪类药物第2位上为哪个取代基时其安定作用最强？A、CH3 B、 Cl C、COCH3 D、 CF374以下哪一项与阿司匹林性质不符？A.、具有退热作用 B、遇湿会水解成水杨酸和醋酸C、极易溶解于水 D、有抗血栓作用 75非甾体类抗炎药的作用机制是：A、抑制花生四烯酸环氧化酶的活性 B、对抗5-羟色胺 C、作用于阿片受体 D、作用于离子通道 76盐酸美沙酮的化学结构是：771-甲基-4-苯基哌啶-4-羧基乙酯是下列哪个镇痛药物的化学名？A、 哌替啶 B、 吗啡 C、美沙酮 D、芬太尼78关于盐酸麻黄碱的说法错误的是：A、 是肾上腺素能受体兴奋剂 B、可与碘化汞钾等多种生物碱沉淀剂生成沉淀C、 易溶于水 D、用于轻中度高血压或肾性高血压及顽固性心功能不全79盐酸吗啡水溶液易被氧化，是结构中含有下列哪种基团？A、 醇羟基 B、 酚羟基 C、双键 D、叔胺基80氯苯那敏与枸橼酸醋酐加热显紫红色，是因分子中含：A、叔胺结构 B、不饱和键 C、酚羟基 D、芳伯胺 81可用于胃溃疡治疗的结构中含呋喃环的药物是：A、氯苯那敏 B、雷尼替丁 C、西替利嗪 D、西咪替丁82下列为钙通道阻滞剂的药物是：83下列哪项叙述与胆碱能受体激动剂不符的？A、乙酰胆碱乙酰基部分为芳环或大基团时，转变为胆碱受体拮抗剂B、乙酰胆碱的亚乙基桥上a位甲基取代，M样作用增强，成为选择性M受体激动剂C、氯贝胆碱的S型异构体