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Newtechnologiesincellculture Content IntroductionComparisonSensortechnologies Introduction bioreactors Introduction bioreactors Capableofbeingoperatedasepticallyforanumberofdays weeksandevenmonthsCapableofgeneratingrepeatableprocessconditionsforanumberofdays weeksandevenmonthsAdequateaerationandagitationshouldbeprovidedtomeetthemetabolicrequirementsofthemicro organismorcellpH Oxygen TemperatureandothercontrolshouldbeprovidedSamplingfacilitiesshouldbeprovidedShouldbesuitableforarangeofprocessesShouldbeconstructedtoensuresmoothinternalsurfaces cleanability Flask TestTubes Shakeflasks Increasedaeration Reducedevaporativeloss Solidsupport Re useable Autoclavable MaybeusedwiththeSensorDishReader Flask sareShakeFlasks FlaskConfigurationsFrom100ulto4 0ml SensorDishReader SDR SensorDishReader SDR Non invasive online pHorDissolvedOxygen NoCalibrationRequired 6 well 24 well Expandable AdditionalSDR slinkintotheBasicSet Upto10SDR sononeLaptop Noadditionalsoftwarerequiredforexpansion SDR sIntegratewith Flasks Flask sIntegratewiththeSensorDishReader EliminateWell plateinconsistency Reduceandequalizeevaporativelossesacrosswell plates ObtainonlinepHordissolvedoxygendataforallwells DOprofiles all24foreachwell plate Polystyrene u Flask SensorFlaskReader SFR TheSensorFlaskReader SFR Shaker mountingblue toothsensorplatform ShakeFlaskswithDOandpHsensors alsosingleDOorpHifdesired Multiplevolumes 125 250 500 1000ml Upto9flasksontheplatformatonetime MicrobialandMammalianApplications MicrobialApplications MonitorpHandDOlevels Ensureaerobicgrowth Followcarbonsourceutilizationandexhaustion AdjustorbiterspeedstomaintainDOlevelsforbetterscalability MammalianApplications AccuratelymonitorpH pCO2levels Adjustbicarbonatelevelsmoreaccurately MonitorDOlevels adjustorbiterspeedsforbetterscalability Software IndividualFlaskCalibration CompleteHardware HardwareIncludes Platform Batteries Bluetoothadapter Software Clamps Bluetoothrangeof 15ft Batterylife 3monthsonasinglecharge platformcanoperateonsinglebattery TheRAMBIO1000 ResonantAcousticMixing ResonantAcousticMixing Allenergygoesintomixingthecontentsoftheflask6foldbetterOTR sthanorbitalshakersduetoincreasedheadspaceexchangeUpto50 fillvolumeinstandardflasks TheApplikonRAM Accessories ClampsandOxy pumpStoppers 250ml 1000ml Singleuseapplications Smallscaleoptions moreR DAppliFlexCellReady Sensortechnologies TraditionalsensorpHandDOSterilizedviaautoclave Sensortechnologies Fluorescent FluorescentlightismeasureforpHandDO Fluorescencepro con Pre sterilizedPre calibrated pH Singleuse reusable DO Measurementthroughwallofvessel pHrangelimitedNotbackwardscompatible controller Canbeinfluencedbymedium pH Additionalcost PRO CON Newtechnologies AppliFlexreusableAppliFlexsinglesensorsusesensor Newtechnologies ReusablestandardSinglesensorsuseSensoroptionalEz Control Smallscalebioreactors Smallscalebioreactorsystem 29 Smallscalebioreactor Communicationviawebbrow
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