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医学文献信息检索作业专业 临床医学 学号 3032012351 姓名 赵高炀 2014年4月22日Pubmed及全文数据库检索练习题1. 禽流感护理方面的文献分析：本题有三个主题概念，即胰岛素、糖尿病和护理检索步骤：#1 胰岛素 #2 糖尿病 #3 护理 #4 #3 and #2 and #1题目：Preparing for pandemic Avian influenza: ensuring mental health services andmitigating panic.检索式：Influenza in BirdsMesh AND Influenza in Birds/nursingMesh检索结果：1. Arch Psychiatr Nurs. 2007 Feb;21(1):64-7.Preparing for pandemic Avian influenza: ensuring mental health services andmitigating panic.Manderscheid RW.Author information: Constella Group, L.L.C., Durham, NC, USA.PMID: 17258112 PubMed - indexed for MEDLINECommentaryPreparing for Pandemic Avian Influenza: Ensuring Mental Health Services and Mitigating PanicRonald W. ManderscheidENSURING MENTAL HEALTH and substance use1 (MH) services and mitigating panic is essential to reducing the severe disruptions associated with the secondary effects of pandemic avian influenza (PAI). PAI will have widespread primary effects of increased morbidity and mortality and the secondary effects of disrupting our economic, health, educational, and community institutions. Ensuring MH services to those experiencing severe loss or incapacity of family and friends; community leaders; and those requiring medical, psychological, and pharmacy services can mitigate both the primary and secondary effects of PAI. Unlike most natural or man-made disasters with which we have previous experience, such as Katrina or the 9/11 terrorist attacks, PAI is very likely to be national in scope and unlikely to be restricted to a local area or region. As a result, themental health strategies that have been effective in the past for localized disasters are not likely to be effective during PAI. A national response will be required and planning must be undertaken now. The purpose of this White Paperwhose intended audience is senior thought leaders, strategists, and decision makersis to present some of our thinking and thereby engender dialogue. We propose six strategies and associated recommendations to address these issues:1. Strategy 1: Plan How to Reprogram FederalMental Health Funds2. Strategy 2: Plan the State and Local Response3. Strategy 3: Support the Private SectorResponse4. Strategy 4: Ensure the Mental Health of Essential Personnel5. Strategy 5: Mitigate Panic6. Strategy 6: Identify and Empower a Lead Federal AgencySTRATEGY 1: PLAN HOW TO REPROGRAM FEDERAL MENTAL HEALTH FUNDSIn an epidemic, many new cases of mental illness are likely to develop, secondary to theepidemic of grief, depression, sleeplessness, and anxiety that will be associated with illness, the fearof illness, and death of loved ones. The incapacitation or death of family, friends, and communityleaders (especially pastors, teachers, social workers, psychologists, physicians, nurses, and othermembers of helping professions) will compound these effects. Sequelae will include longer termdepression, panic disorder, and posttraumatic stress disorder, which in and of themselves increasesstress on family and coworkers, as will the disruption of MH services. It is vital to controlthis bepidemic within an epidemic.”Recommendations1. Develop simple mechanisms to reprogram Federal funds for urgent MH services; createmechanisms to waive any legal and regulatory barriers. 2. Create technical assistance mechanisms to help train and guide staff, both now inpreparation and later to ensure management of MH problems.3. Plan for expanded crisis hotlines (staff, training, scripts, referral mechanisms, and equipment).4. Define simple diagnostic and treatment algorithms for MH; train staff in their use; and stock extra medications.5. Create alternative staffing plansincluding redeploying staff from clinics, hospitals, andother agenciesto fill behind absent andFrom the Constella Group, L.L.C., Durham, NCB 2007 Elsevier Inc. All rights reserved.0883-9417/1801-0005$30.00/0doi:10.1016/j.apnu.2006.10.0031 Substance use is now the preferred term because it doesnot imply blame for a medical condition.64 Archives of Psychiatric Nursing, Vol. 21, No. 1 (February), 2007: pp 64672. 维生素C治疗哮喘的带免费全文的文献题目：Effect of vitamin C administration on leukocyte vitamin C level and severity of bronchial asthma.检索式：Ascorbic Acid/therapeutic useMesh AND Asthma/drug therapyMesh AND loattrfree full textsb 检索结果：1. Acta Med Iran. 2012;50(4):233-8.Effect of vitamin C administration on leukocyte vitamin C level and severity of bronchial asthma.Nadi E1, Tavakoli F, Zeraati F, Goodarzi MT, Hashemi SH.Author information 1Department of Internal Medicine, Shahid Beheshti Hospital, Hamadan University of Medical Sciences, Hamadan, Iran.AbstractOxidative stress mediated by reactive oxygen species is known to contribute to the inflammatory process of bronchial asthma. Reactive oxygen species are released into the bronchial tree by activated inflammatory cells. In this study, we aimed to determine the effect of vitamin C administration on leukocyte vitamin C level as well as severity of asthma. In this double blind clinical trial study we evaluated 60 patients with chronic stable asthma. The patients were divided into two groups (A and B) including 30 patients in each group. Patients in these groups were matched according to their age, weight, height, gender, BMI and drug consumption. In addition to standard asthma treatment (according to stepwise therapy in 4th step of bronchial asthma) in which the patients were controlled appropriately, group A received 1000 mg vitamin C daily and group B received placebo. At the baseline and after one month treatment, non-fasting blood samples were drawn for laboratory evaluations. Asthmatic patients clinical condition was evaluated through standard pulmonary function test (PFT). The mean (SD) leukocyte vitamin C level in group A at the baseline and after one month treatment with 1000 mg/day vitamin C, were 0.0903 (0.0787) g/108 leukocytes and 0.1400 (0.0953) g/108 leukocytes respectively (P0.05). The mean (SD) leukocyte vitamin C level in group B at the baseline and after one month administration of placebo, were 0.0867 (0.0629) g/108 leukocytes and 0.0805(0.0736) g/108 leukocytes respectively. The leukocyte vitamin C level in group A was higher than those of group B after one month treatment with vitamin C and placebo and the difference was statistically significant (P0.05). Comparing PFT (FEV1, FVC and FEV1/FVC) in group B during the study period showed a significant increase in FEV1 (P0.05), while the other two parameters remained unchanged. In group A, who received 1000 mg/day vitamin C, none of the spirometry parameters changed after one month treatment, indicating no effect of vitamin C treatment in the spirometry parameters. 2012 Tehran University of Medical Sciences. All rights reserved.PMID:22592572PubMed - indexed for MEDLINE ORIGINAL REPORTEffect of Vitamin C Administration on Leukocyte Vitamin C Level and Severity of Bronchial AsthmaEbrahim Nadi1, Farnaz Tavakoli1, Fatemeh Zeraati2, Mohamad Taghi Goodarzi3, and Seyed Hamid Hashemi41 Department of Internal Medicine, Shahid Beheshti Hospital, Hamadan University of Medical Sciences, Hamadan, Iran2 Department of Pharmacology, Hamadan University of Medical Sciences, Hamadan, Iran3 Research Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran4 Department of Infectious Disease, Hamadan University of Medical Sciences, Hamadan, IranReceived: 14 Apr. 2011; Received in revised form: 19 Nov. 2011; Accepted: 17 Feb. 2012Abstract- Oxidative stress mediated by reactive oxygen species is known to contribute to the inflammatoryprocess of bronchial asthma. Reactive oxygen species are released into the bronchial tree by activatedinflammatory cells. In this study, we aimed to determine the effect of vitamin C administration on leukocytevitamin C level as well as severity of asthma. In this double blind clinical trial study we evaluated 60 patientswith chronic stable asthma. The patients were divided into two groups (A and B) including 30 patients in eachgroup. Patients in these groups were matched according to their age, weight, height, gender, BMI and drugconsumption. In addition to standard asthma treatment (according to stepwise therapy in 4th step of bronchialasthma) in which the patients were controlled appropriately, group A received 1000 mg vitamin C daily andgroup B received placebo. At the baseline and after one month treatment, non-fasting blood samples weredrawn for laboratory evaluations. Asthmatic patients clinical condition was evaluated through standardpulmonary function test (PFT). The mean (SD) leukocyte vitamin C level in group A at the baseline andafter one month treatment with 1000 mg/day vitamin C, were 0.0903 (0.0787) g/108 leukocytes and 0.1400(0.0953) g/108 leukocytes respectively (P0.05). The mean (SD) leukocyte vitamin C level in group B atthe baseline and after one month administration of placebo, were 0.0867 (0.0629) g/108 leukocytes and0.0805(0.0736) g/108 leukocytes respectively. The leukocyte vitamin C level in group A was higher thanthose of group B after one month treatment with vitamin C and placebo and the difference was statisticallysignificant (P0.05). Comparing PFT (FEV1, FVC and FEV1/FVC) in group B during the study periodshowed a significant increase in FEV1 (P0.05), while the other two parameters remained unchanged. Ingroup A, who received 1000 mg/day vitamin C, none of the spirometry parameters changed after one monthtreatment, indicating no effect of vitamin C treatment in the spirometry parameters. 2012 Tehran University of Medical Sciences. All rights reserved.Acta Medica Iranica, 2012; 50(4): 233-238.Keywords: Leukocyte; Vitamin; AsthmaIntroductionAsthma has been a major focus for clinicians in recent years because both the incidence and mortality appear to be increasing, especially within certain ethnic or geographical groups (1-3). No matter what is the cause, the inci