医学微生物英语教学大纲(6版).doc

Medical MicrobiologyIntroduction Microbiology is the biology of microorganisms that are small, simple structure and not directly visible to unaided eye. It is a bioscience for the study of the evolution, classification, morphology of microbes under certain definite conditions, the law of their life activities, and their interaction with human beings, animals or plants as well as with natural environment. Microorganisms are creatures that are not directly visible to the unaided eye, with dramatical biologic diversity. Viruses , bacteria, fungi, protozoa and some algae are all in this category. The medical microbiology is one of the essential basic sciences. It is the study of Biological characteristics of microorganisms and their relationships with human hosts contents1. Bological properties of microorganism 6h2. Infection 3h3. Immunity to microorganism infection 2h4. Heredity and variation 3h5. Medical microecology, Nosocomial infection, Disinfection and sterilization 2h6. Diagnosis, prevention and cure of aetiology 1h7. Pyogenic bacteria 2h8. Enterobacteriaceae, Vibrios 3h9. Anaerobes 1.5h10. Bacteria infection through respiratory 1.5h11. Bacteria infection through Zoonotic bacteria 2h12. Respiratory Virus 2.5h13. Enterovirus group 2.5h14. Hepatitis Viruses 3h15. Flavivirus Virus 0.5h16. Hemorrhagic Fever Viruses 0.5h17. Herpes Virus 1.5h18. Retrovirus 1.5h19. Other Viruses, Prion, 1.5h20. Fungi 1.5h21. Other microorganism 2hChapter Biological properties of microorganismRequirementBacteria1. Master the cell wall structure of bacteria and their functions2. Master the special structure of bacteria and their functions3. Master the following concepts :1. plasmid 2. capsule 3. spore4.L-form bacterium 5. lipopolysaccharide(LPS)4. Understand the Metabolism of bacteria and their products5. Understand the growth curve of bacteria 6. Understand the cell membrane, cytoplasm, nuclear material of bacteriaVirus1. Master the chemical composition and function of viruses2. Master the major feature of the replication cycle of viruses3. Master the following concepts :1. virion 2. interference 3.prion 4.defective virus(缺陷病毒) 5. abortive infection(顿挫感染)4. Understand the characteristics of Viral Genetics.5. Understand the effects of physical and chemical agents on viruses.Fungus1. Master the genearal characteristics of fungi.(真菌)2. Understand the morphology and culture properties of fungiClass hour: 6 hourContentBacteria1. detailed explain the conception of bacteria, structure, special structure, Gramsstain and chemical composition of bacteria.2. 2. general explain bacterial nutrient materials, bacterial growth and reproduction ang bacterial metabolism. Virus3. detailed explain the conception of virus ,Structure and Chemical Composition and classification of virus.4. intensively explain the Viral Replication cycle（复制周期） adsorption (吸附) ,penetration（穿入）,uncoating（脱壳）,biosynthesis（生物合成）,assembly and release（装配和释放）.3. intensively explain Unnormal multiplication.4. general explain the Viral Genetics Mutations;Effects of Physical andChemical Agents on Viruses. Fungus1. general explain characteristics morphology（形态）, properties,Classification of fungChapter Infection Requirement1. Master the mechanism of bacterial virulence2. Master the resource, chemical composition and pathogenic mechanism of exotoxin and endotoxin3. Master the the pathways of viral infections and the viruses which can result in vertical infection .4. Master the pathogenesis of viral infection and the oncogenic virus associated with human tumors.5. Master the the characteristics of immunity against virus infection6. Master the the antiviral activity of IFN.7. Master the following concepts : 1. vertical transmission 2. latent infection 3. slow virus infection4.Interferon (IFN) 5. neutrilizing antibody 6. CPE 7.infection 8.exotoxin 9. endotoxin8. Understand the classification of IFN and the production of IFN.9. Understand the resource, route and type of bacterial infection.10. Understand the morphology and culture properties of fungiClass hour: 3 hours Content1. intensively explain pathogenesis of bacterial Infection.2. detailed explain the resource, chemical composition, pathogenic mechanism.3. detailed explain the the pathways of viral infections and the type of viral infection,Immunity against virus infection.4. intensively explain Pathogenesis of Viral Infection.5. general explain Epidemiology, examination methods, prevention and treatment, Pathogenicity and immunity diagnosis of fungiChapter Heredity and VariationRequirement1. Master the concept, main characteristic of plasmid and important plasmid of associated mecial.2. Master the main mode of gene transfer and recombination.3. Master the following concepts :1. Plasmid 2.phage 3.transformation 4.conjugation 5.transduction 6.lysogenic conversion 4. Understand the principle of heredity and variation5. Understand the variation phenomenon of bacteria.6. Understand the medical significance of microbic heredity and variation Class hour: 3 hours Content1. general explain the principle of heredity and variation2. detailed explain the variation phenomenon of bacteria.3. detailed explain the mode of phage.4. intensively explain the variation mechanism of bacteria.5. explain the heredity and variation of virus.6. general explain the medical significance of microbic heredity and variation Chapter Medical microecology, Nosocomial infection, Disinfection and sterilizationRequirement1. Master the concept of normal flora and conditioned pathogen2. Master the pathogenic condition and main characteristic of conditioned pathogen.3. Master the following concepts :1.normal flora 2.conditioned pathogen 3.opportunistic infection 4.disinfection 5.sterilization 6.asepsis 7.antiseptic technique4. Understand the concept and research contents of medical microecology.5. Understand .6. Understand the physics methods and chemical methods of disinfection and asepsis.Class hour: 3 hours Content1. detailed explain conditioned pathogen and opportunistic infection.2. explain the concept the mian microorganism, risk factors and prevention and therapy of nosocomial infection.3. detailed explain the concepts of disinfection, sterilization, asepsis and antiseptic technique5. detailed explain moist heat sterilization.6. explain chemical methods of disinfection and asepsis.Chapter Diagnosis, prevention and treatment of aetiologyRequirement1 Master announcements of specimen collection and laboratory diagnosis2 Master the main process of detection of pathogen3 Master the culture of virus4 Understand the significance of serodignosis5 Understand the examination methods of viral infection.Class hour: 1 hours Content1. explain bacteriological diagnosis and serological diagnosis2. explain the diagnosis of virus3. explain the dignosis of fungusChapter Pyogenic bacteriaRequirement1. Master the pathogenic materials, mechanisms of coccus and its disease2. Understand the common properties, examination methods, prevention and treatment of coccusClass hour: 3 hours Content1. intensively explain the pathogenicity of Staphylococcus and Streptococcus2. intensively explain the pathogenicity of S. pneumoniae and Neisseria3. explain the common properties, examination methods of coccusChapter Enterobacteriaceae, VibriosRequirement1. Master the common properties of Bacterium entericum2. Master the pathogenicity of Bacterium entericum3. Master the biological characteristics and pathogenicity of V. choleraae4. Understand the examination methods, prevention and treatment of Bacterium entericum5. Understand the examination methods, prevention and treatment of V. choleraaeClass hour: 3 hours Content1. intensively explain the main biological characteristics and pathogenicity of Shigella2. intensively explain the main biological characteristics and pathogenicity of Salmonella3. detailed explain laboratory examination of Bacterium entericum4. detailed explain Widal test and its result decision5. detailed explain the effect of cholera enterotoxin at pathogenesisChapter AnaerobesRequirement1. Master the biological characteristics and pathogenicity of C. tetani2. Master how to use antitox and anatoxine at disease caused C. tetani3. Understand the biological characteristics of C. perfringens4. Understand pathogenic mechanism and characteristics of clostridial myonecrosis5. Understand the pathogenesis of C. botulinumClass hour: 1.5 hours Content1. intensively explain the biological characteristics, pathogenicity, prevention and treatment of C. tetani2. intensively explain biological characteristics, pathogenic mechanism and characteristics of clostridial myonecrosis3. detailed explain pathogenesis of Clostridum4. explain the the classification of anaerobic bacteria5. explain the the classification, common properties, distribution of Non-spore-forming anaerobesChapter Bacteria infection through respiratoryRequirement1. Master the biological characteristics, pathogenicity and immunity of Mycobacterium2. Master the principle, method, result judgement and significance of tuberculin test3. Master the biological characteristics, pathogenicity, immunity and treatment of C. dipheriae4. Understand the biological properties of L. pneumophilaClass hour: 1.5 hours Content1. intensively explain the biological characteristics, pathogenicity and immunity of Mycobacterium2. intensively explain the principle, method, result judgement and significance of tuberculin test3. detailed explain the biological characteristics, pathogenicity, immunity and treatment of C. dipheriae4. explain the biological properties and pathogenesis of L. pneumophilaChapter Spirochete（螺旋体）Requirementunderstand the characters, examination methods, prevention and treatment of spirochete（螺旋体）Master the characteristics of spirochete（螺旋体）Class hour: 0.5 hours Content1. general explain general properties ,Classification of spirochete（螺旋体）2. general explain Epidemiology, examination methods, prevention and treatment, Pathogenicity and immunity diagnosis of Treponema(密螺旋体), Borrelia（疏螺旋体）, Leptospira（钩端螺旋体）3. detailed explain Pathogenicity of spirochete（螺旋体）Chapter Mycoplasma（支原体）Requirementunderstand the characters,examination methods, prevention and treatment of mycoplasma(支原体)Master pathogenesis of pathogenic mycoplasmaClass hour: 0.5hours Content1. general explain common properties , examination methods, prevention and treatment of mycoplasma(支原体) 2. general explain Epidemiology, and pathogenesis and immunity of mycoplasma(支原体)Chapter Rickettsia（立克次体）Requirementunderstand the characters, examination methods, prevention and treatment of Rickettsia（立克次体）Master the pathogenic Rickettsia（立克次体）Class hour: 0.5hours Content1. general explain common properties of Rickettsia（立克次体） 2. general explain Epidemiology, pathogenesis and pathogenesis and immunity , examination methods, prevention and treatment of Rickettsia（立克次体）Chapter Chlamydiae(衣原体)Requirementunderstand the characters, examination methods, prevention and treatment of chlamydiae(衣原体)Master the characteristics of chlamydiae(衣原体)Class hour: 0.5 hours Content1. general explain general properties of chlamydiae(衣原体) 2. general explain Epidemiology, examination methods, prevention and treatment, Pathogenicity and immunity of chlamydiae(衣原体)Chapter Respiratory virusesRequirementMaster all of the common properties of Influenza viruses Master the common properties, pathogenesis of SARS coronavirusUnderstand the clinical illnesses caused by other respiratory viruses.Class hour: 3 hour Content1. detailed explain Characteristic properties of common respiratory viruses2. intensively explain the pathogenesis of respiratory viruses,Influenza virus,Parainfluenza virus,Measles virus, Mumps virus,Rubella Virus.3. general introduce the examination methods , prevention and Treatment of respiratory viruses infection.4. intensively explain the common properties, pathogenesis of SARS coronavirusChapter Enterovirus Diarrheal VirusRequirementMaster the common properties of enteroviruses.Master the pathogenesis of poliovirus.Master the clinical illnesses caused by Coxackie virus, ECHO virus and New enteroviruses.Master the biological properties and pathogenesis of rotaviruses.Class hour: 2 hour Content1. detailed explain Characteristic properties of common enteroviruses and rotaviruses.2. intensively explain the pathogenesis and immunity of polioviruses and rotaviruses.3. general introduce the the pathogenesis of Coxackie virus, ECHO virus and New enteroviruses.4. general introduce the examination methods , prevention and treatment of enteroviruses and rotaviruses infection.Chapter hepatitis virusRequirementMaster the classification, transmission， examination methods and properties of hepatitis virus.Master the pathogenesis and immunity of HAV,HBV,HCV and HEV.Understand the pathogenesis immunity and examination methods of HDV and other hepatitis viruses.Class hour: 3 hour Content1. detailed explain the classification, transmission ，examination methods and properties of hepatitis virus(esp construction of HBV genome，Ag)2. intensively explain the pathogenesis and immunity of HAV,HBV,HCV and HEV.3. general introduce the pathogenesis immunity and examination methods of HDV and other hepatitis viruses.Chapter Flavivirus and Hemorrhagic Fever VirusRequirementunderstand the common properties of Flavivirus .Master the transmission ,pathogenesis, immunity ,prevention, treatments and of Epidemic B encephalitis virus.understand the transmission ,pathogenesis, immunity ,prevention, treatments and of Dengue fever virus and Russian spring-summer encephalitis virusunderstand the pathogen caused hemorrhage, common properties , Epidemiology, pathogenesis and immunity of Hemorrhagic Fever Viruses.Understand examination methods ,prevention and treatment of Hemorrhagic Fever Viruses infection.Class hour: 2 hour Content1. intensively explain Characteristic properties,transmission, pathogenesis and immunity of Epidemic B encephalitis virus.2. generally explain the pathogenesis and immunity of Dengue fever virus and Russian spring-summer encephalitis virus.3. general introduce the examination methods , prevention and treatment 4. generally explain common properties , Epidemiology, pathogenesis and immunity of Hantaan virus.5. generally explain pathogenesis and immunity of Xing Jiang hemorrhagic virus.6. generally explain the examination methods , prevention and treatment of Hantaan virus and Xing Jiang hemorrhagic virus infection.Chapter HerpesvirusesRequirementMaster the common properties of herpesviruses.Master the classification and associated diseases of herpesviruses.Understand the examination ,prevention and treatments of Herpesvirus Class hour: 1.5 hours Content1. detailed explain the common properties of herpesviruses,the Characteristic properties of HSV,VZV,EBV,CMV.2. intensively explain pathogenesis and immunity of HSV,VZV,EBV,CMV.3. general introduce the examination methods , prevention and treatment of HSV,VZV,EBV,CMV.Chapter RetrovirusesRequirementund