氧化石墨烯简介与应用策略PPT课件

氧化石墨烯的应用策略,1,.,1985,1991,2004,-NovoselovKS,GeimAK,MorozovSV,etal.ElectricfieldeffectinatomicallythincarbonfilmsJ.science,2004,306(5696):666-669.,2,.,-SzabT,BerkesiO,ForgP,etal.EvolutionofsurfacefunctionalgroupsinaseriesofprogressivelyoxidizedgraphiteoxidesJ.Chemistryofmaterials,2006,18(11):2740-2749.,3,.,-MarcanoDC,KosynkinDV,BerlinJM,etal.ImprovedsynthesisofgrapheneoxideJ.ACSnano,2010,4(8):4806-4814.,4,.,-MkhoyanKA,ContrymanAW,SilcoxJ,etal.Atomicandelectronicstructureofgraphene-oxideJ.NanoLetters,2009,9(3):1058-1063.,STEMADF,石墨烯,氧化石墨烯（GO）,还原氧化石墨烯（rGO）,5,.,宏观应用,6,.,-ChenC,YangQH,YangY,etal.SelfAssembledFreeStandingGraphiteOxideMembraneJ.AdvancedMaterials,2009,21(29):3007-3011.,气液界面自组装成膜,7,.,-DikinDA,StankovichS,ZimneyEJ,etal.PreparationandcharacterizationofgrapheneoxidepaperJ.Nature,2007,448(7152):457-460.,定向流动成膜,8,.,-CoteLJ,KimF,HuangJ.LangmuirBlodgettassemblyofgraphiteoxidesinglelayersJ.JournaloftheAmericanChemicalSociety,2008,131(3):1043-1049.,L-B成膜,9,.,-LiuZ,LiZ,XuZ,etal.Wet-spuncontinuousgraphenefilmsJ.ChemistryofMaterials,2014,26(23):6786-6795.,湿纺,10,.,-ZangmeisterCD,MaX,ZachariahMR.RestructuringofgrapheneoxidesheetsintomonodispersenanospheresJ.ChemistryofMaterials,2012,24(13):2554-2557.,11,.,-HanTH,HuangYK,TanATL,etal.SteametchedporousgrapheneoxidenetworkforchemicalsensingJ.JournaloftheAmericanChemicalSociety,2011,133(39):15264-15267.,12,.,微观应用,13,.,-KimJ,CoteLJ,KimF,etal.GrapheneoxidesheetsatinterfacesJ.JournaloftheAmericanChemicalSociety,2010,132(23):8180-8186.,ConcentrationDependentAmphiphilicity,pHDependentAmphiphilicity,SizeDependentAmphiphilicity,14,.,-TungVC,HuangJH,TevisI,etal.Surfactant-freewater-processablephotoconductiveall-carboncompositeJ.JournaloftheAmericanChemicalSociety,2011,133(13):4940-4947.,15,.,-BalapanuruJ,YangJX,XiaoS,etal.AGrapheneOxideOrganicDyeIonicComplexwithDNASensingandOpticalLimitingPropertiesJ.AngewandteChemie,2010,122(37):6699-6703.,16,.,-LuCH,YangHH,ZhuCL,etal.AgrapheneplatformforsensingbiomoleculesJ.AngewandteChemie,2009,121(26):4879-4881.,-ChangH,TangL,WangY,etal.GraphenefluorescenceresonanceenergytransferaptasensorforthethrombindetectionJ.AnalyticalChemistry,2010,82(6):2341-2346.,17,.,1、只需要在一端标记荧光标签的，无需淬灭端。2、荧光淬灭效果显著，背景噪音小。,-HeY,WangZG,TangHW,etal.LowbackgroundsignalplatformforthedetectionofATP:whenamolecularaptamerbeaconmeetsgrapheneoxideJ.BiosensorsandBioelectronics,2011,29(1):76-81.,MAB：aptamermolecularbeacons,18,.,-ZhangM,YinBC,WangXF,etal.Interactionofpeptideswithgrapheneoxideanditsapplicationforreal-timemonitoringofproteaseactivityJ.ChemicalCommunications,2011,47(8):2399-2401.,ArgHisLysTrpTyrPhe,静电,芳香氨基酸,19,.,-ShiX,GuW,PengW,etal.SensitivePb2+ProbeBasedontheFluorescenceQuenchingbyGrapheneOxideandEnhancementoftheLeachingofGoldNanoparticlesJ.ACSappliedmaterials&interfaces,2014,6(4):2568-2575.,20,.,-LiuZ,RobinsonJT,SunX,etal.PEGylatednanographeneoxidefordeliveryofwater-insolublecancerdrugsJ.JournaloftheAmericanChemicalSociety,2008,130(33):10876-10877.,21,.,22,.,-ZhangS,YangK,FengL,etal.InvitroandinvivobehaviorsofdextranfunctionalizedgrapheneJ.Carbon,2011,49(12):4040-4049.,-BaoH,PanY,PingY,etal.ChitosanFunctionalizedGrapheneOxideasaNanocarrierforDrugandGeneDeliveryJ.Small,2011,7(11):1569-1578.,23,.,24,.,25,.,1、处理贝壳，剪下外套膜和鳃；2、添加50mMTris-Hcl（pH8.5）缓