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1超细粉体技术对小儿腹泻外敷凝胶透皮吸收的影响A1A0A1A0A3A2A3A2A4A5A6A7A8A9A10A11A12A13A14A15A16A17A18A19A20A21A22A23A24A25A26A27A28A29A30A31A32A33A34A35A22A23A24A36A37A38A39A40A39A41A25A42A43A44A45A46A47A48FRANZA49A50A51A52A53A54A55A56A57A58A59A60A61A62A59A63A64A65A66A67A68A69A70A71A72A73A74A75A76A77A68A78A79A80A81A82A80A72A83A84A85A86A87A88A89A88A89A88A90A91A92A93A94A95A96A97A98A99A100A101A102A103A104A105A106A107A105A108A109A110A111A107A108A112A113A114A115A116A117A118789180A1191072232G/A120CM2HA121A110A122A123A124A125A126A127A128A129A130A120P005A121A131A132A133A134A135A136A137A138A139A140A141A142A143A144A145A146A147A148A149A150A151A152A153A154A155A156A157A158A159A160A161A131A162A163A164A163A164A165A166A167A168A169A170A171A172A173A174A175A176A177A173A178A179A180A173A181A182A183A184THETRANSDERMALABSORPTIONEFFECTOFULTRAPOWDERTECHNOLOGYONXIAOERFUXIEWAIFUGELABSTRACTOBJECTIVETOINVESTIGATETHEEFFECTOFULTRAPOWDERTECHNOLOGYONTRANSDERMALABSORPTIONOFEUGENOLINXIAOERFUXIEWAIFUGELMETHODSTHERELEASETESTOFTWOKINDSOFXIAOERFUXIEWAIFUGELWASASSAYEDWITHFRANZDIFFUSIONCELLBYTHEINDEXOFCUMULATIVERELEASINGOFEUGENOLINUNITAREAINVITRORESULTSTHEPERCUTANEOUSABSORPTIONPROCESSOFEUGENOLINTWOKINDSOFGELSWERECONFORMEDTOZEROORDERRELEASINGMODELANDTHETRANSDERMALRATESWERE789180AND1072232G/A185CM2HA186RESPECTIVELYTHEREWASSIGNIFICANTDIFFERENCEBETWEENTWOKINDSOFGELA185P005A186CONCLUSIONTHETECHNOLOGYOFSUPERFINECOULDFAVORTRANSDERMALABSORPTIONOFEUGENOLANDIMPROVEBIOAVAILABILITYKEYWORDSXIAOERFUXIEWAIFUGELULTRAPOWDEREUGENOLTRANSDERMALABSORPTIONA187A188A189A190A191A192A193A194A195A196A197A198A199A200A201A202A203A204A205A206A207A208A209A210A211A212A213A214A215A216A217A218A219A220A221A222A223A224A225A226A227A228A229A230A231A213A192A232A225A233A234A235A236ZL031529909A215A237A196A238A239A213A240A241A232A242A243A244A226A245A246A247A248A249A250A249A251A215A252A253A254A255A199A233A241A243A244A127A0A1A2A3A215A135A4A247A248A5A215A233A117A6A215A139A7A8A9A10A242A11A12A13A14A226A26A15A215A11A235A7A11A12A9A140A226A16A17A209A24A18A29A200A38A19A20A226A38A21A218A219A220A221A222A223A22A187A188A189A190A191A192A193A194A23A243A24A18A226A25A27A215A150A28A22A140A30A31A217A213A214A32A33A220A249A218A219A220A225A34A226A35A228A187A188A189A190A191A192A193A194A36A37A221A191A39A23A40A41A215A153A42A73A23A243A24A18A43A44A291A40A41A214A6311A158A45FW100A230A239A115A46A47A220A48A49A99ZHWY100A230A50A51A220A48A49A99A166A52FRANSA221A191A53A199A54A77A168A55A56A57A58A59A60A61A62A64A65A66A64A67A68A69A55A56A57A58A70NY03034A71A72A74A75A76A59A78A79A80A701973A71A81A82A83A84A85A86A81A87A88A81A89A90A91A85A92A93A94A68A95A96A97EMAILA98HYYUAN2002SOHUCOM2A225A100A99791A230A101A251A204A102A103A104A45A99A173A105LC10ATA239A12A106A107A108A109A158A99SPDIOAA179A191A110A111A45A99N2000A108A109A177A112A113A99KROMASILC18A108A109A114A99SARTORIUSBP211A230A116A118A119A120A99KQ250BA230A218A121A122A123A124A45A2912A213A125A126A128A233A197A129A209A197A198A212A213A214A77A198A130A131A132A133A134A213A214A136A137A100A99A197A129A138A22A141A125A77A207A236725A208200209A100A77A231A142A213A125A143A240A225A125A110A144A145A238A146A100A99A213A147A77A108A109A148A100A2913A40A41A149A240A217A151A228A187A152A215A219A154A21520A2202GA215A221A155A231A156A213A157A159A149A240A231A160A238A146A77SYXKA22720020053A236A100A292A40A41A203A16121A193A194A162A125A226A225A34A230211A32A33A193A194A226A225A34A230A231A203A117A213A214A217A239A115A46A47A220A48A49A220A48A9A32A33A220A77A163120A232A164A100A215A126A195A165A193A194A201A167A169A170A171A172A29212A218A219A193A194A226A225A34A230A241A231A203A117A174A213A214A215A217A50A51A220A48A49A220A48A175A218A219A220A77D9030MA100A215A126A195A165A193A194A201A167A169A170A171A172A2922A221A191A23A243A24A18A40A41221A176A221A152A243A226A225A34A174A219A154A187A152A215A2A178A231A180A215A217A181A182A183A223A184A185A187A152A186A242A187A215A253A188A189A190A191A192A236A193A194A249A196A199A200A224A201A202A203A204A205A206A250A209A204A210A211A212A214A215A216A218A222A206A223A225A226A228A229A233A234A235A228A237A238A239A240A242A243A244A245A246A206A247A233A234A235A228A248A251A252A254A255A206A55A223A194222A30A0A175A1A2A55A233A234A235A228500MLA206A8912GA32A79A33A102A34A3A4A206A5A620MINA206A152A237A7A37A149A206A38A71A55A223A194223A36A8A9A10A39A2471A214A8A204A22A11A12A13A12A13A39A247A42A223A14A15A1FRANZA9A10A44A206A40A44A46A41A16A69A17A44A206A210A18A46A19A20A16A30A0A18A206A73A21A23A44A47A4815CMA206A82A24A9A10A25A26177CM2A206A30A0A44A49A26A46165MLA194A50A254A255A61A27A28A204A51A210A29A21A23A44A210A31A206A192A236A193A25A53A40A206A29A192A236A193A40A35A43A45A52A54A56A57A5805GA206A152A57A58A59A204A205A30A60A62A242A164A63A194A64A65A50A21A23A44A51A210A29A30A0A44A40A206A30A0A44A47A66A67A30A0A175A206A68A70A72A130A247A140370A22010A74A1A75A76A228A77A248A206A169A78A80A81A206A83A84100R/MINA194A35A43A1401A2062A2064A2066A2068A20612A201A85A85A86A87A22A19616MLA30A0A175A229A88A206A90A91A92A93A176A94A95A1A96A243A30A0A175A194A22A196A1A229A88A175A97045MA98A99A38A212A38A71A65A100A30A101A103HPLCA35A104A206A181A210A105A106A107A108A95A206A241A109A1102A111A112A113A114A115A116A25A26A117A26A3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