合肥国家同步辐射实验室X射线相位衬度成像取得重大突破

1、合肥国家同步辐射实验室X射线相位衬度成像取得重大突破X射线相位衬度成像是在世纪之交蓬勃发展起来新型成像技术，它弥补了传统X射线成像技术对轻元素材料不敏感的不足，为生命科学、材料科学、信息科学以及医疗诊断、安全检查和工业产品检测等展现了美好的应用前景。然而，迄今为止发展的X射线相位衬度成像方法太繁琐、曝光时间过长、辐射剂量过高，阻碍了这种新型成像技术的应用。中国科学技术大学国家同步辐射实验室吴自玉研究员领导的成像研究小组，经过几年的努力，发现X射线正面入射和背面入射的两张投影像中，吸收衬度具有对称性，而折射衬度具有反对称性。根据这一原理，提出了X射线相位CT新方法，实验结果表明新方法克服了以往X

2、射线相位衬度成像方法中的不足，具有简便、快速和低辐射剂量的优点，可以和现有的医学X射线CT技术相结合，形成操作简便、辐射剂量低的X射线相位CT新技术。相关研究论文发表在最近一期的PNAS期刊上PNAS 107, 13576 (2010)，被审稿人誉为“近二十年来X射线成像的重大突破”。这项研究成果受到国际同行的高度关注，被今年8月在美国芝加哥举行的第十届X射线显微术国际会议（XRM 2010，Chicago）邀请做特邀报告，获得国际多位著名X射线成像专家的高度评价，一致认为这项研究成果具有重大应用前景。另外，在8月份第十届X射线显微术国际会议上，中国科学技术大学国家同步辐射实验室与上海光源联手

3、合作，高票赢得下一届2012年X射线显微术国际会议的举办权（XRM 2012，上海-合肥）。 Breakthrough on X-ray Phase-contrast ImagingNational Synchrotron Radiation Laboratory (NSRL)，University of Science and Technology of China made a great breakthrough in X-ray phase-contrast computed tomography (CT) in 2010.The simple, fast and low radiat

4、ion dose X-ray phase-contrast CT technique was newly put forward by the research team led by Prof. WU Ziyu, director of NSRL. It is developed based on the principle that the absorption contrast is the same but the refraction contrast opposite between front projection and back projection. The new tec

5、hnique set the prerequisites for fast and low-dose phase-contrast X-ray imaging techniques in the future. The findings were published in PNAS, 107, 31, 13576-13581 (2010). In comparison, the existing X-ray phase-contrast imaging technique is subjected to long exposure time, high radiation dose and c

6、omplicated operation, which impairs its wide application. Experiments show that the new technique can address all these shortages with lower radiation dose and simpler operation. With its distinct advantages, the new technique has drawn worldwide attention. NSRL was invited to deliver a report on it in the 10th International Conference on X-ray Microscopy (XRM) in Chicago in August, 2010. The report was highly praised by famous experts who believed that the new technique would show great promise in the future. During the conference, NSRL along with Shangh