医学动物模型A

1、12BC/MC醋酸菌醋酸菌属属Acetobacter土壤杆菌土壤杆菌属属Agrobacterium根瘤菌根瘤菌属属Rhizobium八叠球菌八叠球菌属属Sarcina图1.1 细菌纤维素，(C6H10O5) nFigure 1.1 Bacterial cellulose, (C6H10O5) n 4Shi Z J, et al. RSC Advances, 2012, 2: 10401046 bacterial cellulose (BC) was produced by Gluconacetobacter xylinus。lBC has many unique. BC is highly h

2、ydrophilic and has properties of good water retentiveness, high permeability, optimal gelatinization,and high mech-anical strength.lBC has been widely applied in medical and industrial fields, not just in medical science, but also in cosmetics and veterinary medicineThe establishment of the full-ski

3、n injury model in a BALB/c mouse The inflammatory cells were mainly neu-trophils and showed few lymphocytes and macrophages. In addition, there was he-avier inflammation in the wound tissue in xeno-transplant groups than that in the BC or gauze groups on day 14. Unlike the gro-ups which showed more

4、inflamma-tory response, the cells of the thick BC group were mainly fibroblasts and few macro-phages. TGF 转化生长因子-（transforming growth factor-,TGF-)FGF 成纤维生长因子（fibroblast growth factor,FGF）图4.16 厚BC组和小鼠皮肤组的愈合率。11图4.17 （A）厚BC组在第17天，伤口处毛发生长浓密；（B）小鼠皮肤组的伤口处的毛发生长稀疏。图4.19治疗第11天，测量厚BC组和小鼠皮肤组中小鼠的TGF-1和bFGF在小鼠血清中的浓度（n = 3）。Compared to the other groups, the thick BC group showed a better healing effect, even better than the mouse