冻干机手动和自动操作指引

1、5.1. Freeze-dryingOperation操作用户操作设备进行冻干程序操作Loggingincontrolsystemisneededbeforeoperatingtheequipment.Inthecontrolsystem,freeze-dryingprocesscanbedonethrough2methods.操作用户若需要对设备进行操作需要先登入控制系统。在控制系统中对于冻干可通过2种方式来完成AutomaticControl自动控制ManualControl手动控制5.1.1 Operatorrunsautomaticcontroltodofreeze-dryingope

2、ration操作用户运行自动控制进行冻干流程操作Inautomaticcontrol,switchallthecontrolcomponentstoautomaticcontrolstatusatfirstandthensettherecipeparameters.Afterthat,will'aplpARTAUTO.Userclicksthe“STARTAUTO.buttontostartautomaticprogram.在自动控制中需要先切换把所有的控制部件切换到自动控制状态，然后设置配方参数，当设置好配方参数后开始自动”按钮会显示，用户点击开始自动”按钮启动自动程序。Contro

3、lcomponentsopenandcloseautomaticallyaccordingtoautomaticprogram.Atthemeanwhile,statusof“AUTOontherightuppercornerwillbecomegreenandtheinterfaceswitchbutton“FREZE_DRYINGontheleftlowercornerwillalsohassmallgreenframe.自动程序运行后控制部件按程序自动运行开启和关闭，同时在界面右上角的”自动”状态会显示绿色、左下角的冻干”界面切换按钮也会有绿的小方框显示。Theoperationstat

4、usofautomaticprogramcanbedisplayedbyclickingthe“Probuttononrightlowerpartandswitchingtoprogramoperationalstatus.自动程序的运行状况可点击界面右下部分的程序”按钮切换到程序运行状态显示。5.1.2 ControlComponentsSwitchtoAutomaticControlStatus控制部件切换到自动控制状态Clickanycontrolcomponentsontheinterfaceanddigitalsignatureofcomponentscontrolwillpopup

5、.Afterenteringtheusernameandpassword,componentcontrolpicturewillappear.Click“ALLTHECOMPONENTSCHANGETOAUTObesidecomponentspictureontheMODEbuttonandallthecomponentscontrolturntoautomaticmodel.Userscanfindoutstatusswitchfromthestatusiconinterface.点击界面的任何控制部件会弹出部件控制的电子签名，输入操作用户和密码后显示部件的控制画面，点击”全部切换为自动”按

6、钮后所有的控制部件切换为自动模式，用户可从界面部件画面旁的状态图标可看出状态的切换5.1.3 RecipeParametersSetting设置配方参数Beforerunningtheautomaticprograms,recipeparametersshouldbesetanddownloadedtothePLCinordertoruntheprogramaccordingtodesignedprocess.Ifaboveoperationwillnotbedone,“STARTAUTO.buttospwiyandautomaticprogramwillnotstart.在运行自动程序前需要

7、设定配方参数并且下载到可编程控制器里（PLC）以让程序按设好的工艺进行运行，若不进行上述操作则自动”按钮不会显示，自动程序也将无法启动。1. .OperationButtons操作按钮No.ButtonName按钮名称ButtonInstructions按钮说明1View查看Viewtherecipe配方的查看2Modify修改Modifytherecipe配方的修改3New新建Buildnewrecipe,newrecipenameshouldbeenteredbeforebuilding配方的新建，在新建配方前需要输入新配方名4Save保存Savetherecipe.Relevantrec

8、ipesshouldbesavedinthecomputeraftermodificationforfreeze-dryingoperationatnexttime.配方的保存，在修改配方后需要对相应的配方进行保存操作，保存到电脑系统中以供下次冻干操作使用5Download下载Recipedownloading.DownloadtherecipetoPLCinordertoprovideparametersforautomaticprogramrunningoffreeze-drying.配方的下载，使配方数掂下载到可编程控制器里供冻干自动程序运行提供参数。6Print打印Printingth

9、erecipethroughprinteroutput配方的打印，通过打印机输出7Delete删除Deletetherecipe.Thisoperationisnotadvisedevenunreasonablerecipeexists.配方的删除，此操作不建议使用，即使启/、合理的配方也不建议删除操作2. ParametersInstruction参数说明Controlprocessoffreeze-dryingisdividedinto4partsincludingFreezingControl(ProgramSection16),CondenserFreezing(ProgramSect

10、ion7,8),PrimaryDrying(ProgramSection919),andDryingAnalysis(ProgramSection2023).The9thstepsectioninPrimaryDryingispre-vacuumizingphaseandinthisphasewarming-upcontrolwillnotbedone.Thetemperaturetobesetshouldbeconsistentwiththetemperaturesettingvalueinthe6thstepsection.Eachstepsectioncanincludetemperat

11、uresetting,vacuumsetting,andvacuumcontrolchoiceandpressure-upcontrolchoiceaccordingtocontrolrequirements.冷冻干燥控制流程分为4部分包括预冷(程序段16段)、后箱冷却(程序段7、8段)、第一次升华干燥(程序段919段)、解析干燥(程序段2023段)，升华干燥中的第9步段是预抽真空的阶段，此阶段不进行升温控制，设置的温度需要和第6步段的温度设定值一致，每个步段按控制需求可包括温度设置、真空设置、真空控制选择和压力升控制选择。FreezingControlpartdoesnotincludeva

12、cuumsetting,vacuumcontrolchoiceandpressure-upcontrolchoice.The7thstepsectioninCondenserFreezingpartiscondensertemperaturesettingandthe8thstepsectionismaintainingtimeaftercondensertemperatureisreached(atleastset20min).预冷部分不包含真空设置、真空控制选择和压力升控制选择。后箱冷却部分第7步段是后箱温度设置，第8步段是达到后箱温度后维持的时间(至少设置20分钟)。The9thstep

13、sectioninPrimaryDryingispre-vacuumizingphaseandinthisphasewarming-upcontrolwillnotbedone.Thetemperaturetobesetshouldbeconsistentwiththetemperaturesettingvalueinthe6thstepsection.Ifchoosepressure-upcontrolbuttoninthe19thstepsection,thepressure-upcontrolwillstartsafterthe19thstepsectionandthiscontroli

14、ncludes2parametertesttimeandpressure-upsettingvalue.升华干燥中的第9步段是预抽真空的阶段，此阶段不进行升温控制，设置的温度需要和第6步段的温度设定值一致，若在第19步段行若选择压力升控制选择按钮，则在19步段结束后进行压力升控制，压力升控制包括2个参数:测试时间和压力开设定值。AsthesamewithPrimaryDrying,ifchoosepressure-upcontrolinthe23thstepsectioninDryingAnalysispart,thecontrolwillstartsafterthe23thstepsecti

15、onandthatcontrolincludes2parametertesttimeandpressure-upsettingvalue.解析干燥部分和升华干燥一样若在第23步段行若选择压力升控制选择按钮，则在23步段结束后进行压力升控制，压力升控制包括2个参数：测试时间和压力升设定值。5.1.4 AutomaticProgramStart自动程序启动UserclicksAftersettingtherecipeparameters,“STARTAUTO.buttonwillappears.the“STARTAUTO.buttontostartautomaticprogram.当设置好配方参数

16、后开始自动”按钮会显示，用户点击开始自动”按钮启动自动程序。5.1.5 ProcessStatusInquiry>ParameterModificationandForcedComponentControl过程状态的查询、参数修改和部件强制控制RecipeParameter配方参数ControlParameter控制参数OperationParameter运行参数T讨工，I爆邮d讨4功自功D.ocn尊阪二事统瞥书，手声出日：配方君!4力*冈AcnVLtMilVIirFiR宾主融止SRTS"Erzr星5"we已W.卡口T"Iff内区三甲7|二必口韶|e吐山电击

17、也H片号才压力信号F>!KFlr1OJnJji1!2七min.iiSOJO七I14GUOpuZinJ5MrJTdHJ*OJO七0nin.寸|诈印再通市（聃*时闽防«巾苒空m帼用母力瑁啊生理后推抬却!00t0103式"斜QJ0VO.M»E±-1Fnin1jiJF-H帕iziMrtuu.iM*MMDElb4Eimln13-QQotcoipt4FminOJl弋,OO杜血1cja1止.gyq叩iztu.niiL-1。O"0MBiMil1Mt0*叩EtNTVran.;哈rarv也城吐就nrDdn1NM七0.M0述stQiliai静所干找，KDflp

18、y21JL七Q.MQ4rp，23OJO弋OUDDc±ii1nib1：.力一-*廿州-小fli±-,9mu卜地七/Mi凡-T1*1七'自濯君打过现状志a示！七110.100Efcar*苴01OldOd>4!E竽包叱明1o.mi.»IO.D免*帛VMEUAF1iHESAtBl0WZ然iirtilFT10M8M1/ITiiy1niri1njFiTflsn*o；o禹一r-!1r-!1rB!TI：3PTB.ftffiSTfl1pvjtfjiiraiJPU，_H，B件flRunningstatusduringautomaticprogramoperationca

19、nbedisplayedbyclickingthe“Program“buttonatrightlowerpartofinterfaceandswitchingtoprogramrunningstatusastheabovepicture.自动程序运行时的运行状况可点击界面右下部分的程序”按钮切换到程序运行状态显示，如上图Interfaceparametermainlyconsistsofrecipeparameter,controlparameterandoperationparameter.界面参数主要分3部分组成，配方参数、控制参数和运行参数。5.1.6 RecipeParameter己方

20、参数RecipeParameteristhemaintechnicalparameteroffreeze-dryingoperation.Ifonlywanttomodifythetechnicaldataofcurrentbatchduringoperation,usercandosomesettingsatthisinterface.Exceptthedataoffirststepsectioncannotbemodifiedafterautomaticprogramstarting,otherdatacanallbemodifiedduringtheoperation.Pleasesee

21、thehapterofsettingrecipeparametersfordetailinformation.配方参数是冷冻干燥运行的主要工艺参数，在运行过程中若只希望修改本批次运行的工艺数据可在此界面进行设置。除第1步段的数据在自动程序运行后不能修改，其他的数据在运行过程中均可修改。详细说明请见设置配方参数章节。5.1.7 ControlParamete控制参数ControlParameterisaccessoryparameterofautomaticprogramoperationbesidesthetechnicalrecipeparameter.Itsinstructionisasf

22、ollow:控制参数是除工艺配方参数以外自动程序运行的辅助参数，说明如下表。NO.ParameteEtems#数项Instruction说明1TEMP.CONTROLDEVIATION温度控制上偏差Upperdeviationofparameterprecisioncontroloftemperaturesetting温度设置参数精度控制上偏差2TEMP.CONTTOLDEVIATION(L)温度控制下偏差Lowerdeviationofparameterprecisioncontroloftemperaturesetting温度设置参数精度控制下偏差3VACCONTDEVIATION真空控制

23、上偏差Upperdeviationofparameterprecisioncontrolofvacuumsetting真空设置参数精度控制上偏差4VACCONTDEVIATION(L)真空控制下偏差Lowerdeviationofparameterprecisioncontrolofvacuumsetting真空设置参数精度控制下偏差5VACALARMVALUE真空报警设定值Vacuumalarmparameter.IfchambervacuumhigherthanthissettingvalueduringPrimaryDryingoperation,theheatingcontrolwil

24、lbeclosedandcoolingwillbedonetothechamber.Whenvacuuminthechamberislowerthanthesettingvacuumvalue,heatingcontrolwillrestarts.真空报警参数，升华干燥阶段运行后若前箱真空高于此设定值则加热控制关闭，同时对前箱进行制冷，当箱内真空低于配方设定真空值则恢复加热控制6PID_CYCLEPID周期设定值PIDControlCirculationCyclePID控制循环周期7PID_ACCURACYPID精度设定值PIDControlAccuracyPID控制精度8PID_PROPOR

25、TIONPID比例设定值PIDControlProportionParametersPID控制比列参数9PID_INTEGRALPID积分设定值PIDControlIntegralParametersPID控制积分参数10PID_DIFFERENTIALPID微分参数设定值PIDControlDifferentialParametersPID控制微分参数OperationParameter运行参数OperationParameterisstatusdisplayduringautomaticprogramoperatingperiod.Detaildisplayisasfollow:运行参数是

26、自动程序运行过程中的状态显示，具体显示如下图No.ParameteEtem参数项Instruction说明1RUNNINGSTEP运行步段号Numberofrunningstepsection运行的步段号2RUNNINGSECTION步段说明Instructionofrunningstepsection运行步段的说明3TEMP.SELECT温度设定值Temperaturesettingvalueofrunningstepsection运行步段的温度设定值4TEMP.OILINLET导热油进口温度Temperaturerunningvalueofrunningstepsection运行步段的温度

27、运行值5VAC.SELECT真空度设定值Vacuumsettingvalueofrunningstepsection运行步段的真空设定值6VAC.CHAMBER箱内真空度Vacuumrunningvalueofrunningstepsection运行步段的真空运行值7TIMESELECT步段时间设定值Timsettingvalueofrunningstepsection运行步段的时间设定值8TIMERUNNINGSELECT步段时间运行值Timrunningvalueofrunningstepsection运行步段的时间运行值5.1.8 AutomaticProgramStop自动程序停止Au

28、tomaticprogramstopsinsequence,andindicatinglightofelectricitycabinetwillturngreenforindication.Userclicks“STOPAUTO.buttontostopautomaticprogram.自动程序按顺序运行结束，电气柜的指示灯会亮绿灯指示，用户点击停止自动按钮停止自动程序。5.1.9 Userrunsmanualcontroltodofreeze-dryingoperation操作用户运行手动控制进行冻干流程操作Userscanmanuallycontrolcomponentsinthesyst

29、emduringmanualcontrol(automaticcontroldoesnotrun).Forthesamecomponent,thereare3kindsofbuttonsforoperationcontrol.在手动过程中(自动控制没有运行)用户可对系统中的部件进行手动控制。对同一个部件有3种按钮进行操作控制。Manual:thisoperationcanforcedlystartthecontrolcomponents;手动：操作可强制开启控制部件Automatic:thisoperationcanmakecontrolcomponentsjoininautomaticlog

30、icalcontrolduringautomaticoperation;自动：在自动运行过程中使控制部件参与自动逻辑控制Stop:thisoperationcanstoptheopencontrolcomponents.停止：操作可停止开启的控制部件ManualControl_lllWillbedisplayedbesidethecontrolcomponentafteroperation部件手动控制操作结束在控制部件旁显AllcomponentsturntoautomaticcontrolWillbedisplayedbesideallcontrolcomponentsafteroperat

31、ion部件全部切换自动控制操作结束在所有控制部件旁AutomaticControlStopControlWillbedisplayedbesidecontrolcomponentafteroperation部件停止控制操作结束在控制部件Note：Inmanualcontrol,openvacuumpumpmorethan20minbeforeopeningthesmallbutterflyvalve.注：在手动控制下，开启小蝶阀前先要开启真空泵20分钟以上。Exceptthemanualcomponentcontrol,otherfunctionalcontrolsareneededtomee

32、tthenormaltechnicalrequirementsofautomaticprogram.Theyareasfollow:除手动部件控制外若要保证自动程序的正常工艺需求，还需要其他的功能控制的参与，见下表No.ControlItem控制项Instruction说明1TEMPCONTROL温度控制Circulationpumpstarts,HEATINGCONTROLcanberunifthevacuumisnormal.循环泵开启，真空止常则可进行加热控制IfOILINLETTEMP>HEATINGTEMP.(C)beforetemperaturecontrolstarts,h

33、eatingcontrolwillstarts.温度控制启动前若导热油进口温度>加热设定温度(C)则进行加热控制。PIDtemperaturecontrolanddeviationalarmingtreatmentaredonetotheheater.Ifthetemperatureistoohigh-OILINLETTEMP>HEATINGTEMP.(C)+TEMP.Colddopingvalvewillopen.加热器进行PID温度控制并且进行偏差报警处理，温度开的太高，导热油进口温度>加热设定温度(C)+偏差温度则掺冷阀打开。CONTROLDEVIATION,coldd

34、opingvalvewillopenandchambertemperaturegoesdown.WhenOILINLETTEMP<HEATINGTEMP.(C),colddopingvalvewillclose.控制偏差则掺冷阀打开，止匕时前箱隔板温度降低，当导热油进口温度<加热设定温度(C),掺冷阀关闭。IfOILINLETTEMP<HEATINGTEMP.(C)beforetemperaturecontrolstarts,coolingcontrolwillbedoneandheaterandcolddopingvalvewillnotattendthecontrol.温

35、度控制启动前若导热油进口温度<加热设定温度(C)则进行制冷控制。加热器、掺冷阀/、参与控制。IfOILINLETTEMP>HEATINGTEMP.(C)+TEMP.CONTROLDEVIATION,platecoolingvalveopensandcondensationvalvecloses,temperatureofchamberisolatingplategoesdown.导热油进口温度>加热设定温度(C)+温度控制偏差，则板冷阀打开冷凝阀关闭，止匕时前箱隔板温度降低。WhenOILINLETTEMP<HEATINGTEMP.(C),condensationval

36、veopensandplatecoolingvalvecloses.当导热油进口温度<加热设定温度(C)则冷凝阀打开板冷阀关闭。2VAC.CONTROL真空控制Thesameastemperaturedeviationcontrol,whenCHAMBERVACUUM<VACUUMCONTROLSELECT(Pa)-VACCONTDEVIATIONduringfreeze-dryingprocess,aerificationvalvewillopen.AndifCHAMBERVACUUM>VACUUMCONTROLSELECT(Pa)+VACCONTDEVIATION(L),

37、theaerificationvalvewillclose.和温度的偏差控制一样，冷冻干燥运行过程中箱内真空值<真空控制设定值(Pa)-真空偏差值，则掺气阀打开-箱内真空值,真空控制设定值(Pa)+真空偏差值，则掺气阀关闭。3VAC.ALARM真空报警CHAMBERVACUUM>VAC.ALARMCONTROL,heatingcontrolclosesandalarmingstarts.CHAMBERVACUUM<EVACUATIONCONTROL(Pa),Alarmdisable.箱内真空度,报警真空设定值，则加热控制关闭，同时报警提示，箱内真空度<疏散控制设定值(P

38、a),则报警解除。5TAMPONADEAfterfreeze-dryingprogram,TAMPONADECONTROLcanbeCONTROL压塞控制started.Tamponadecontrolofhydraulicpressuredeclinewillstartautomatically.WhenSHELFPRESSWITCHsignalisjudged,hydraulicpressurecontrolstopsandTAMPONADECONTROLends.在冻干程序结束后可进行压塞控制，液压自动启动下降进行压塞，当判断压塞控制信号后液压控制停止压塞结束SettingParamet

39、ersofManualOperationforCoolingContro泠冻控制手动运行设定参数NO.ControlItems控制项Instruction说明1HEATINGTEMP.(C):加热温度设定值SettingValueofTemperatureControl温度控制设定值2HEATINGTIME(Min)加热时间设定值TemperatureControlTime温度控制时间3EVACUATIONCONTROL(Pa)真空控制设定值SettingValueofVacuumAlarm真空控制设定值4ALARMCONTROL真空报警设定值Vacuumalarmingparameter.W

40、henchambervacuumishigherthanthissettingvalueduringPrimaryDryingprocess,heatingcontrolcloseandalarmstarts.真空报警参数，升华阶段运行后若前箱真空高于此设定值则加热控制关闭，同时报警提示5TEMP.CONTROLDEVIATION温度控制上偏差Upperdeviationofparameterprecisioncontroloftemperaturesetting温度设置参数精度控制上偏差6TEMP.CONTTOLDEVIATION(L)温度控制下偏差Lowerdeviationofparam

41、eterprecisioncontroloftemperaturesetting温度设置参数精度控制下偏差7VACCONTDEVIATION真空控制上偏差Upperdeviationofparameterprecisioncontrolofvacuumsetting真空设置参数精度控制上偏差8VACCONTDEVIATION(L)真空控制下偏差Lowerdeviationofparameterprecisioncontrolofvacuumsetting真空设置参数精度控制下偏差Useroperatesequipmenttododeicingprogram操作用户操作设备进行化霜程序操作Operatingusersshouldloginthecontrolsystemfirstlyiftooperatetheequipment.Deicingcanbecompletedby1meth