Epsilon-momfluorothrin-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEEpsilon-momfluorothrinCat. No.: HY-111634CAS No.: 1065124-65-3分式: CHFNO分量: 385.35作靶点: Others作通路: Others储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 5 mg/mL (12.98 mM; Need ultrasonic)Mas

2、s Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.5950 mL 12.9752 mL 25.9504 mL5 mM 0.5190 mL 2.5950 mL 5.1901 mL10 mM 0.2595 mL 1.2975 mL 2.5950 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验 请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百

3、分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 0.5 mg/mL (1.30 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 0.5 mg/mL (1.30 mM); Clear solution3. 请依序添加每种溶剂： 10% DMSO 90% corn oilSolubility: 0.5 mg/mL (1.30 mM); Clear solutio

4、n1/2 Master of Small Molecules 您边的抑制剂师www.MedChemEBIOLOGICAL ACTIVITY物活性 Epsilon-momfluorothrin种合成的 I 型拟除菊酯杀剂，可以活化组成性雄甾烷受体 (constitutiveandrostane receptor (CAR)，可诱导中肿瘤的发 1。IC50 & Target Constitutive androstane receptor 1REFERENCES1. Okuda Y, et al. Editors Highlight: Mode of Action Analysis for Rat

5、 Hepatocellular Tumors Produced by the Synthetic PyrethroidMomfluorothrin: Evidence for Activation of the Constitutive Androstane Receptor and Mitogenicity in Rat Hepatocytes. Toxicol Sci. 2017 Aug1;158(2):412-430.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021-589