2-O-4-C-Methyleneuridine-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemE2-O,4-C-MethyleneuridineCat. No.: HY-111639CAS No.: 200435-92-3分式: CHNO分量: 256.21作靶点: Nucleoside Antimetabolite/Analog作通路: Cell Cycle/DNA Damage储存式: 4C, sealed storage, away from moisture* In solvent : -80C, 6 months; -20C, 1 mo

2、nth (sealedstorage, away from moisture)溶解性数据体外实验 DMSO : 125 mg/mL (487.88 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 3.9030 mL 19.5152 mL 39.0305 mL5 mM 0.7806 mL 3.9030 mL 7.8061 mL10 mM 0.3903 mL 1.9515 mL 3.9030 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验 请根据您的实

3、验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.08 mg/mL (8.12 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.08 mg/mL (8.12 m

4、M); Clear solution3. 请依序添加每种溶剂： 10% DMSO 90% corn oilSolubility: 2.08 mg/mL (8.12 mM); Clear solution1/2 Master of Small Molecules 您边的抑制剂师www.MedChemEBIOLOGICAL ACTIVITY物活性 2-O,4-C-Methyleneuridine (Compound 15a)种双环核苷。REFERENCES1. Sharma VK, et al. Chemoenzymatic convergent synthesis of 2-O,4-C-methyleneribonucleosides. J Org Chem. 2014 Jul 3;79(13):6336-41.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fa