Atazanavir-sulfate-BMS-232632-sulfate-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEAtazanavir sulfateCat. No.: HY-17367ACAS No.: 229975-97-7Synonyms: BMS-232632 sulfate分式: CHNOS分量: 802.93作靶点: HIV; HIV Protease作通路: Anti-infection; Metabolic Enzyme/Protease储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 mont

2、hs-20C 1 month溶解性数据体外实验 DMSO : 166 mg/mL (206.74 mM; Need ultrasonic and warming)H2O : 0.1 mg/mL (insoluble)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 1.2454 mL 6.2272 mL 12.4544 mL5 mM 0.2491 mL 1.2454 mL 2.4909 mL10 mM 0.1245 mL 0.6227 mL 1.2454 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期

3、限。BIOLOGICAL ACTIVITY物活性 Atazanavir sulfate (BMS-232632 sulfate)种选择性的 HIV-1蛋酶抑制剂，于治疗艾滋病毒感染，是第个批准每天使次的蛋酶抑制剂 1。Atazanavir sulfate (BMS-232632 sulfate)是CYP3A4 的底物和抑制剂，也 P-糖蛋的抑制剂和诱导剂 2。IC50 & Target HIV-1 protease 11/2 Master of Small Molecules 您边的抑制剂师www.MedChemE户使本产品发表的科研献 Faculty of Pharmacy in Hrade

4、c Krlov Department of Pharmacological and Toxicology. University of Oxford. 2019 Jul. bioRxiv. April.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Havlir DV, et al. Atazanavir: new option for treatment of HIV infection. Clin Infect Dis. 2004 Jun 1;38(11):1599-604.2. Wood R. Atazanavir: its role in HIV treatment. Expert Rev Anti Infect Ther. 2008 Dec;6(6):785-96.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;