0104年中大细生期末试卷02

1、细胞生物学期末试卷任课金200226班级一、填空题(每空 0.5 分，共 10 和的腔中被被修饰蛋白通过并形成进行转运。有两种类型的包被细胞生物学期末试卷任课金200226班级一、填空题(每空 0.5 分，共 10 和的腔中被被修饰蛋白通过并形成进行转运。有两种类型的包被小泡，一是，它介导小泡，它介导。低密度的脂蛋白通过其表面的DNA8400压缩倍表一二三四五六七八总 1.Indicate whether each of the following sements is true of the G1 phase of the cell cycle, the S phase, the G2 ph

2、ase, or the M phase. A given sement may be true of any,allornoneofthephases.（0.55分TheamountofnuclearThenuclearenvelopehecelloSisterchromatidsseparatefromeach(d) twillneverdivideagainarelikelytobehisTheprimary1.Indicate whether each of the following sements is true of the G1 phase of the cell cycle,

3、the S phase, the G2 phase, or the M phase. A given sement may be true of any,allornoneofthephases.（0.55分TheamountofnuclearThenuclearenvelopehecelloSisterchromatidsseparatefromeach(d) twillneverdivideagainarelikelytobehisTheprimarycellwallofaplantcellChromosomesarepresentasdiffuse,extended(g)Thisphas

4、e ispart(h) Mitoticcydinisatitslowest(i)ACdkproteinishe(j)Acellcyclehasbeenhis)传递信号。）)三、选择题(请将正确Ethylalcoholis的代号填入括号，每题1分，共15heliver.Youwouldexpectalcoholtohavewhichoffollowingeffects三、选择题(请将正确Ethylalcoholis的代号填入括号，每题1分，共15heliver.Youwouldexpectalcoholtohavewhichoffollowingeffectsonlivercells? Nucl

5、earGrowthofthesmooth GrowthofroughNoneofthe2. Which of the following proteins endoplasmic reticulum?（）would not be ）he 3.Whichcytochrome P450 glucose6-phosphatase signal peptidasethefollowingexplainswhymicrosomescantbeseeninviewed with the electron ）far too artifactsofhomogenizationandtransparentto

6、actually can be seen in electron micrographs of If you compared the proteins in a cis Golgicompartment with）in a trans the the compartment, you would he two compartments are he cis compartment are glycosylated and modifiedamino not modified.c. the whereas those the trans compartment in cis compartme

7、nt are glycosylated, glycosylated and those in the modifiedaminod.the proteins of the cis compartment are trans n those of WhichtypeofvesicleofthetransGolginetworkwouldbemost）tocarryhormonesdestinedforregulateda.lysosomalb.clathrin-coated all of theascolchicine,whichtthefollowingwouldbe）Cell Mitosis

8、andb.clathrin-coated all of theascolchicine,whichtthefollowingwouldbe）Cell Mitosisandmeiosiswouldnotracellular location of Alloftheabovewouldyou dissolve the membrane from anelleswouldbeact flagellum, using detergent Triton X-100. Next you soak the axoneme in a these ）peripheraltubulesperipheraltubu

9、lesandcentraltubules,butnosidearmsorATPase peripheral tubules, central tubules, side arms, and ATPase and a 8. Thesarcoplasmicreticulumegralmembranetand）bindto tropomyosinandactionWhenchromatinistreatedwithnonspecificnucleases,whatisthelengthofreultingofrandomnumbersofbase60base8base 200base10. What

10、omeres）a.Theyprotectthechromsomesfromdegradationbyb.Theysofchromosomesfromfusingwithonec.Theyarerequiredforcompletechromosomald.allof the11. Cyclinconcentrationsarehighestduringwhichperiodsofthecellb.Theysofchromosomesfromfusingwithonec.Theyarerequiredforcompletechromosomald.allof the11. Cyclinconce

11、ntrationsarehighestduringwhichperiodsofthecell（）earlyS earlylateM andlatea. 产生H)d四、简答题(选做 4 题，每题 5 分，20 1.Howdoesregulatedsecretiondifferfromconstitutive2.Dynamicinstabilitycausesmicrotubuleseithertogrowortobe ogueoftetcanbedrawnfromthefollowingWhen an animal cell is treated with colchicine, its mic

12、rotubules depolymerize and virtually disappear. If the colchicine is then washed away, the MTs appear again, beginning at the centrosome and elongating outward at about the rate (1 gm/min) atwhichtubulinpolymerizesin五、计算与推理(第 1 题必做，2、3 选一题，每题 5 etcanbedrawnfromthefollowingWhen an animal cell is trea

13、ted with colchicine, its microtubules depolymerize and virtually disappear. If the colchicine is then washed away, the MTs appear again, beginning at the centrosome and elongating outward at about the rate (1 gm/min) atwhichtubulinpolymerizesin五、计算与推理(第 1 题必做，2、3 选一题，每题 5 分，共 10 1.In anelectronmicro

14、graphofa humanchromosomespread,you observea thicklengthofabout900nmandanapparentdiameter of 30nm,whichisforthesolenoidstructureofcondensedfiber? me,fortthereisone helicalturnofsolenoidper30nmalongthe2. One of the functions of the mitotic Cdk (the MPF protein kinase) is to cause precipitous drop in c

15、yclin concentration halfway through M phase. Describe of mightdden decrease and sible mechanisms by which A hat inhibits certain proteolytic enzymes (proteases) is normally o the bloodstreamby liver cells. This inhibitor protein,antitrypsin, isabsentthe bloodstream of patients who carry a t results

16、in a single amino he protein.Antitrypsing e,because of the activity of proteases. Surprisingly, when the mutant antitrypsin is the bloodstream of patients who carry a t results in a single amino he protein.Antitrypsing e,because of the activity of proteases. Surprisingly, when the mutant antitrypsin

17、 is laboratory, it is ive as the normal antitrypsin at inhibiting proteases. Why doesthe ioncause the disease? Think of nsibilityandwaysinwhichyoucoulddistinguishn六、比较题（每题 5 分，共 10 分1. Compare and contrast the following: cytoplasmic dynein vs. kinesin七、综合问答题(任选一题，20 八、附加题（每题 5 分，共 15 分eExtractstcanbedrawnfromthefollowingnondividingfrogheG2phasecouldinducethecellwerefoundtocontaintofthesestructureswere