Pericyazine-Propericiazine-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEPericyazineCat. No.: HY-14263CAS No.: 2622-26-6Synonyms: Propericiazine; RP 8909分式: CHNOS分量: 365.49作靶点: Dopamine Receptor作通路: GPCR/G Protein; Neuronal Signaling储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 mon

2、th溶解性数据体外实验 DMSO : 250 mg/mL (684.01 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.7361 mL 13.6803 mL 27.3605 mL5 mM 0.5472 mL 2.7361 mL 5.4721 mL10 mM 0.2736 mL 1.3680 mL 2.7361 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验 请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄的储备液，再依次添加助溶剂

3、(为保证实验结果的可靠性，体内实验的作液，建议您现现配，当天使；澄的储备液可以根据储存条件，适当保存；以下溶剂前的百分指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.08 mg/mL (5.69 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.08 mg/mL (5.69 mM); Clear solution1/2 Master of Small Mo

4、lecules 您边的抑制剂师www.MedChemEBIOLOGICAL ACTIVITY物活性 Pericyazine (Propericiazine)第代抗精神病药物，被作短期管理严重 焦虑状态和精神病的辅助药物。Pericyazine (Propericiazine)种选择性的 D2 多巴胺受体 (D2-dopamine receptor) 拮抗剂。IC50 & Target D2-dopamine receptor 2REFERENCES1. Morley KC, et al. Pericyazine in the treatment of cannabis dependence i

5、n general practice: a naturalistic pilot trial. Subst Abuse Rehabil.2012 May 28;3:43-7.2. Farde L, et al. D1- and D2-dopamine receptor occupancy during treatment with conventional and atypicalneuroleptics.Psychopharmacology (Berl). 1989;99 Suppl:S28-31.3. Divac N, et al. Second-generation antipsychotics and extrapyramidal adverse effects. Biomed Res Int. 2014;2014:656370.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;