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1、大脑高级皮层功能障碍演示文稿第一页,共三十七页。优选大脑高级皮层功能障碍第二页,共三十七页。cognition functionour ability to perform complex intellectual behaviors such as speaking and writing navigating our way around our environment recognizing other people comprehending time 第三页,共三十七页。Cerebral hemisphereCerebellumBrain stem第四页,共三十七页。dominant
2、 hemisphere The side of the brain that controls writing and speech is called the dominant hemisphere and the other side is the non-dominant hemisphere.The left hemisphere is dominant in over 90% of right-handed people and in about 60% of left-handed people . 第五页,共三十七页。FRONTAL LOBE第六页,共三十七页。1.primary
3、 motor cortexthis is located in the percentral gyrus and is concerned with motor function of the opposite side of the body 第七页,共三十七页。Supplementary motor and premotor corticesthese areas are concerned with coordinating and planning complex movements .第八页,共三十七页。Symptoms from lesions of the motor corte
4、xcontralateral mono-or hemiparesis and facial weakness Supplementary motor and premotor cortices disorders of complex motor planning.第九页,共三十七页。2. Brocas area the motor or expressive centre for the productions of speech (dominant hemisphere only ).第十页,共三十七页。Symptoms from lesions of the Brocas area ex
5、pressive dysphasia :This comprises non-fluent, hesitant speech with intact comprehension.The patient knows what he or she wants to say but has difficulty finding the correct words ,often producing the wrong word. The ability to repeat words is better than spontaneous speech. Handwriting is also ofte
6、n poor.第十一页,共三十七页。3.Prefrontal cortexthe anterior and orbital parts of the frontal cortex govern personality ,emotion, initiative and the ability to plan.第十二页,共三十七页。Symptoms from lesions of the Prefrontal cortex causes altered behaviors, including :social disinhibition loss of initiative and interes
7、tinability to solve problems with loss of abstract thought impaired concentration and attention without intellectual or memory decline 第十三页,共三十七页。4.The cortical micturition centre this region lies in the paracentral lobule and is involved in the cortical inhibition of voiding of the bladder and bowe
8、l.第十四页,共三十七页。Symptoms from lesions of the cortical micturition centre Incontinence of urine and/or faeces Milder symptoms are frequency and urgency of micturition第十五页,共三十七页。5.Frontal eye fieldthis is involved in making eye movements to the contralateral side.第十六页,共三十七页。Symptoms from lesions of the F
9、rontal eye fieldgaze paresis impairment of eye movements to the contralateral side.This is most commonly seen in a large middle cerebral artery stroke and carries a worse prognosis.rightward gaze第十七页,共三十七页。PARIETAL LOBE第十八页,共三十七页。1.Primary somatosensory cortex located in the postcentral gyrus concer
10、ned with perceiving complex somatosensory stimuli from the contralateral side of the face and body第十九页,共三十七页。Symptoms from lesions of the Primary somatosensory cortex Discriminative sensory impairment of the opposite side of the face and limbs 第二十页,共三十七页。3. Use of numbers, e.g. calculation( dominant
11、 hemisphere)第二十一页,共三十七页。Gerstmanns syndromeinability to differentiate the right and left sides of the body, inability to distinguish the fingers of the hands(finger agnosia),impairment of calculation (dyscalculia) impairment of writing (dysgraphia).dominant hemisphere第二十二页,共三十七页。4.Integration of sen
12、soryIntegration of somatosensory ,visual,and auditory information this allows awareness of the body and its surroundings appropriate movement of the body, and constructional ability. 第二十三页,共三十七页。Symptoms from lesions of the parietal lobeApraxiathe dominant parietal lobe Bilateral ideomotor and ideat
13、ional apraxia: the non-dominant parietal lobe Constructional apraxia Dressing apraxia 第二十四页,共三十七页。Apraxia(the dominant parietal lobe )inability to carry out a sequence of tasks when there is normal comprehension and intact motor and sensory function Ideomotor apraxia occurs when a patient fails to c
14、opy an action, ideational or conceptual apraxia is more profound ,e.g.the patient fails to understand use of tools and objects at a basic level.第二十五页,共三十七页。Symptoms from lesions of the parietal lobeTopographical disorientationthe patient cannot find his or her way around normally familiar spaces e.g
15、.home.第二十六页,共三十七页。Symptoms from lesions of the parietal lobeContralateral sensory inattention: neglect of the opposite side of the body For example ,a hemiplegic patient may ignore the paralysed side or there may be denial of the hemiplegia(anosognosia).第二十七页,共三十七页。TEMPORAL LOBE第二十八页,共三十七页。1. Wernic
16、kes areain the posterior part of the superior temporal gyrus, concerned with comprehension of written and spoken language.第二十九页,共三十七页。Symptoms from lesions of the Wernickes areareceptive dysphasia impaired comprehension of speech and written language . fluent but words are replaced with partly corre
17、ct words and an incorrect word related to the word intended (paraphasia)or newly created meaningless words (neologisms)The speech does not make sense and the patient has poor insight into the problem.第三十页,共三十七页。2. auditory cortices The dominant temporal lobe is important for the comprehension of spo
18、ken words the non-dominant for the appreciation of sounds and music. 第三十一页,共三十七页。Symptoms from lesions of the auditory cortex Auditory agnosia: inability to recognize sounds e.g. ringing of a bell ,whistling of a kettle ,a melody (non-dominant hemisphere).Cortical deafness: bilateral lesions of the
19、primary auditory cortices and is uncommon. Auditory hallucinations can occur in temporal lobe epilepsy.第三十二页,共三十七页。3.The limbic system the olfactory and gustatory cortices lie in the medial temporal lobe. The limbic system is important in memory. learning and emotion.第三十三页,共三十七页。Symptoms from lesions of the limbic systemOlfactory and gustatory hallucinations :arise from lesions within the medial temporal lobe ,particula
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